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Toshihide Yamashita

Toshihide Yamashita

D-Index & Metrics

Neuroscience

D-Index
70
Citations
17500
World Ranking
2515
National Ranking
57

Overview

Toshihide Yamashita is a researcher affiliated with Osaka University in Japan. Their academic work spans multiple disciplines within neuroscience, medicine, and biochemistry, genetics, and molecular biology, with a significant focus on neurological and cellular mechanisms.

Their publication record includes research in prominent areas such as neuroinflammation, neurodegeneration, neuroplasticity, and nerve injury and regeneration. Yamashita has contributed to studies addressing spinal cord injury, immune cells in cancer, and multiple sclerosis research. The main topics covered in their work are:

  • Neuroinflammation and Neurodegeneration Mechanisms
  • Neurogenesis and neuroplasticity mechanisms
  • Axon Guidance and Neuronal Signaling
  • Nerve injury and regeneration
  • Spinal Cord Injury Research
  • Immune cells in cancer
  • Multiple Sclerosis Research Studies

Yamashita's recent research papers include the following:

  • Cellular senescence in white matter microglia is induced during ageing in mice and exacerbates the neuroinflammatory phenotype (2023, Communications Biology)
  • Neuroplasticity related to chronic pain and its modulation by microglia (2022, Inflammation and Regeneration)
  • Recent insights into peroxisome biogenesis and associated diseases (2020, Journal of Cell Science)
  • Inhibition of HDAC increases BDNF expression and promotes neuronal rewiring and functional recovery after brain injury (2020, Cell Death and Disease)
  • Microglia as therapeutic target in central nervous system disorders (2020, Journal of Pharmacological Sciences)

Their collaborative network includes frequent co-authors such as Takahide Itokazu, Yuki Fujita, Hiroshi Tsujioka, and Oluwaseun Fatoba.

Yamashita regularly publishes in scientific journals including Neuroscience Research, Communications Biology, Cell Death and Disease, bioRxiv (Cold Spring Harbor Laboratory), and IBRO Neuroscience Reports.

Their work spans key subfields such as neurology, cellular and molecular neuroscience, molecular biology, immunology, and developmental neuroscience.

In addition to journal contributions, Yamashita has contributed to book publications, including a chapter in "Role of Micronutrients in Brain Health" published under Nutritional Neurosciences in 2022.

Best Publications

  • Layer V cortical neurons require microglial support for survival during postnatal development

    Masaki Ueno;Yuki Fujita;Tatsuhide Tanaka;Tatsuhide Tanaka;Yuka Nakamura

  • The p75 receptor acts as a displacement factor that releases Rho from Rho-GDI.

    Toshihide Yamashita;Masaya Tohyama

  • Neurotrophin Binding to the p75 Receptor Modulates Rho Activity and Axonal Outgrowth

    Toshihide Yamashita;Kerry Lee Tucker;Yves-Alain Barde

  • The p75 receptor transduces the signal from myelin-associated glycoprotein to Rho

    Toshihide Yamashita;Haruhisa Higuchi;Masaya Tohyama

  • Induction of aquaporin-4 water channel mRNA after focal cerebral ischemia in rat.

    Masaaki Taniguchi;Toshihide Yamashita;Eiji Kumura;Michio Tamatani

  • RGMa inhibition promotes axonal growth and recovery after spinal cord injury

    Katsuhiko Hata;Masashi Fujitani;Yuichi Yasuda;Hideo Doya

  • Tumor necrosis factor inhibits neurite outgrowth and branching of hippocampal neurons by a Rho-dependent mechanism

    Harald Neumann;Rüdiger Schweigreiter;Toshihide Yamashita;Katja Rosenkranz

  • miR-124a is required for hippocampal axogenesis and retinal cone survival through Lhx2 suppression

    Rikako Sanuki;Akishi Onishi;Chieko Koike;Rieko Muramatsu

  • Cloning and Functional Expression of a Brain Peptide/Histidine Transporter

    Toshihide Yamashita;Shoichi Shimada;Wei Guo;Kohji Sato

  • Axon growth inhibition by RhoA/ROCK in the central nervous system.

    Yuki Fujita;Toshihide Yamashita

  • Temporal Changes in Cell Marker Expression and Cellular Infiltration in a Controlled Cortical Impact Model in Adult Male C57BL/6 Mice

    Xuemei Jin;Hiroshi Ishii;Zhongbin Bai;Takahide Itokazu

  • Microglia in central nervous system repair after injury.

    Xuemei Jin;Toshihide Yamashita

  • Cytoplasmic p21Cip1/WAF1 regulates neurite remodeling by inhibiting Rho-kinase activity

    Hiroyuki Tanaka;Toshihide Yamashita;Minoru Asada;Shuki Mizutani

  • Myelin-associated Glycoprotein Inhibits Microtubule Assembly by a Rho-kinase-dependent Mechanism

    Fumiaki Mimura;Satoru Yamagishi;Nariko Arimura;Masashi Fujitani

  • FLRT2 and FLRT3 act as repulsive guidance cues for Unc5‐positive neurons

    Satoru Yamagishi;Falko Hampel;Katsuhiko Hata;Daniel del Toro

  • The therapeutic effects of Rho-ROCK inhibitors on CNS disorders

    Takekazu Kubo;Atsushi Yamaguchi;Nobuyoshi Iwata;Toshihide Yamashita

  • PKA phosphorylates the p75 receptor and regulates its localization to lipid rafts.

    Haruhisa Higuchi;Toshihide Yamashita;Hideki Yoshikawa;Masaya Tohyama

  • RGMa modulates T cell responses and is involved in autoimmune encephalomyelitis

    Rieko Muramatsu;Takekazu Kubo;Masahiro Mori;Yuka Nakamura

  • Rho-ROCK inhibitors as emerging strategies to promote nerve regeneration.

    Takekazu Kubo;Katsuhiko Hata;Atsushi Yamaguchi;Toshihide Yamashita

  • Intraspinal rewiring of the corticospinal tract requires target-derived brain-derived neurotrophic factor and compensates lost function after brain injury

    Masaki Ueno;Yasufumi Hayano;Hiroshi Nakagawa;Toshihide Yamashita

  • Cloning of a lymphatic peptide/histidine transporter.

    Kazuko Sakata;Toshihide Yamashita;Mitsuyo Maeda;Yoshinori Moriyama

  • Epidermal growth factor receptor localized to exosome membranes as a possible biomarker for lung cancer diagnosis.

    T Yamashita;H Kamada;S Kanasaki;Y Maeda

Frequent Co-Authors

Hideki Mochizuki
Hideki Mochizuki Osaka University
Haruhiko Kishima
Haruhiko Kishima Osaka University
Kohji Sato
Kohji Sato Hamamatsu University
Masaaki Murakami
Masaaki Murakami Hokkaido University
Freda D. Miller
Freda D. Miller University of British Columbia
Masashi Ikeda
Masashi Ikeda Nagoya University

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