World's Best Scientists 2026 revealed!
Toshiyuki Takai

Toshiyuki Takai

D-Index & Metrics

Immunology

D-Index
84
Citations
28225
World Ranking
1358
National Ranking
53

Toshiyuki Takai publication distribution in Immunology in 2026

The chart shows the distribution of publications by all Research.com ranked scientists in the field of Immunology in 2026. The highlighted bar marks where Toshiyuki Takai sits on this spectrum.

62–71 publications: 9 scientists 72–81 publications: 23 scientists 82–91 publications: 40 scientists 92–101 publications: 72 scientists 102–111 publications: 86 scientists 112–121 publications: 108 scientists 122–131 publications: 150 scientists 132–141 publications: 160 scientists 142–151 publications: 159 scientists 152–161 publications: 189 scientists 162–171 publications: 166 scientists 172–181 publications: 181 scientists 182–191 publications: 188 scientists 192–201 publications: 187 scientists 202–211 publications: 178 scientists 212–221 publications: 158 scientists 222–231 publications: 168 scientists 232–241 publications: 159 scientists 242–251 publications: 160 scientists 252–261 publications: 148 scientists 262–271 publications: 116 scientists 272–281 publications: 125 scientists 282–291 publications: 115 scientists 292–301 publications: 111 scientists 302–311 publications: 95 scientists 312–321 publications: 97 scientists 322–331 publications: 97 scientists 332–341 publications: 99 scientists 342–351 publications: 96 scientists 352–361 publications: 68 scientists 362–371 publications: 76 scientists 372–381 publications: 71 scientists 382–391 publications: 71 scientists 392–401 publications: 62 scientists 402–411 publications: 54 scientists 412–421 publications: 41 scientists 422–431 publications: 63 scientists 432–441 publications: 53 scientists 442–451 publications: 31 scientists 452–461 publications: 42 scientists 462–471 publications: 40 scientists 472–481 publications: 29 scientists 482–491 publications: 34 scientists 492–501 publications: 30 scientists 502–511 publications: 23 scientists 512–521 publications: 41 scientists 522–531 publications: 29 scientists 532–541 publications: 28 scientists 542–551 publications: 16 scientists 552–561 publications: 18 scientists 562–571 publications: 18 scientists 572–581 publications: 17 scientists 582–591 publications: 17 scientists 592–601 publications: 17 scientists 602–611 publications: 19 scientists 612–621 publications: 13 scientists 622–631 publications: 12 scientists 632–641 publications: 11 scientists 642–651 publications: 16 scientists 652–661 publications: 9 scientists 662–671 publications: 5 scientists 672–681 publications: 13 scientists 682–691 publications: 12 scientists 692–701 publications: 6 scientists 702–711 publications: 6 scientists 712–721 publications: 9 scientists 722–731 publications: 9 scientists 732–741 publications: 6 scientists 742–751 publications: 11 scientists 752–761 publications: 10 scientists 762–771 publications: 7 scientists 772–781 publications: 12 scientists 782–791 publications: 7 scientists 792–801 publications: 5 scientists 802–806 publications: 1 scientists 807+ publications: 100 scientists
62 publications 807+

This scientist: 308 publications — 65th percentile

65% of scientists in this discipline score the same or lower.

The last bar groups every scientist with 807 publications or more.

Toshiyuki Takai D-index placement in Immunology in 2026

The chart shows the D-index (discipline H-index) distribution of Immunology scientists ranked by Research.com in 2026. The highlighted bar marks where Toshiyuki Takai sits on this spectrum.

40–41 D-Index: 28 scientists 42–43 D-Index: 91 scientists 44–45 D-Index: 157 scientists 46–47 D-Index: 192 scientists 48–49 D-Index: 175 scientists 50–51 D-Index: 188 scientists 52–53 D-Index: 177 scientists 54–55 D-Index: 155 scientists 56–57 D-Index: 194 scientists 58–59 D-Index: 201 scientists 60–61 D-Index: 197 scientists 62–63 D-Index: 201 scientists 64–65 D-Index: 173 scientists 66–67 D-Index: 167 scientists 68–69 D-Index: 172 scientists 70–71 D-Index: 199 scientists 72–73 D-Index: 184 scientists 74–75 D-Index: 133 scientists 76–77 D-Index: 162 scientists 78–79 D-Index: 127 scientists 80–81 D-Index: 121 scientists 82–83 D-Index: 125 scientists 84–85 D-Index: 121 scientists 86–87 D-Index: 102 scientists 88–89 D-Index: 96 scientists 90–91 D-Index: 75 scientists 92–93 D-Index: 72 scientists 94–95 D-Index: 74 scientists 96–97 D-Index: 66 scientists 98–99 D-Index: 68 scientists 100–101 D-Index: 49 scientists 102–103 D-Index: 60 scientists 104–105 D-Index: 54 scientists 106–107 D-Index: 36 scientists 108–109 D-Index: 23 scientists 110–111 D-Index: 52 scientists 112–113 D-Index: 41 scientists 114–115 D-Index: 34 scientists 116–117 D-Index: 25 scientists 118–119 D-Index: 28 scientists 120–121 D-Index: 11 scientists 122–123 D-Index: 20 scientists 124–125 D-Index: 27 scientists 126–127 D-Index: 19 scientists 128–129 D-Index: 20 scientists 130–131 D-Index: 16 scientists 132–133 D-Index: 17 scientists 134–135 D-Index: 14 scientists 136–137 D-Index: 15 scientists 138–139 D-Index: 9 scientists 140–141 D-Index: 11 scientists 142–143 D-Index: 9 scientists 144–145 D-Index: 9 scientists 146–147 D-Index: 7 scientists 148–149 D-Index: 7 scientists 150–151 D-Index: 7 scientists 152–153 D-Index: 5 scientists 154–155 D-Index: 8 scientists 156 D-Index: 6 scientists 157+ D-Index: 96 scientists
40 D-Index 157+

This scientist: 84 D-Index — 73rd percentile

73% of scientists in this discipline score the same or lower.

The last bar groups every scientist with 157 D-Index or more.

Overview

Toshiyuki Takai is affiliated with Tohoku University in Japan and has contributed extensively to research in immunology and microbiology, with additional work spanning the fields of medicine and neurology. Their research interests focus primarily on immune cell function and interactions, cell adhesion molecules, immune cells in cancer, neuroinflammation and neurodegeneration mechanisms, and immune response and inflammation. Additional topics addressed in their work include monoclonal and polyclonal antibodies research as well as galectins and cancer biology.

Their research outputs have been published in a range of academic venues, notably including:

  • International Immunology
  • The Tohoku Journal of Experimental Medicine
  • bioRxiv (Cold Spring Harbor Laboratory)
  • SSRN Electronic Journal
  • The EMBO Journal

Frequent collaborators in their research include:

  • Mei-Tzu Su
  • Shota Endo
  • Takaomi C. Saido
  • Taisuke Tomita
  • So Itoi

A selection of recent papers authored by Toshiyuki Takai includes:

  • "Astrocytic phagocytosis is a compensatory mechanism for microglial dysfunction," published in 2020 in The EMBO Journal
  • "LILRB4 promotes tumor metastasis by regulating MDSCs and inhibiting miR-1 family miRNAs," published in 2022 in OncoImmunology
  • "INPP5D modulates TREM2 loss-of-function phenotypes in a β-amyloidosis mouse model," published in 2023 in iScience
  • "Blockade of checkpoint ILT3/LILRB4/gp49B binding to fibronectin ameliorates autoimmune disease in BXSB/Yaa mice," published in 2021 in International Immunology
  • "TLR7/8 stress response drives histiocytosis in SLC29A3 disorders," published in 2023 in The Journal of Experimental Medicine

Their work often addresses complex immune regulatory mechanisms and disease models, involving both neurological and immunological dimensions. This research is characterized by interdisciplinary approaches connecting cellular immunology with pathological conditions.

Best Publications

  • Primary structure of Electrophorus electricus sodium channel deduced from cDNA sequence.

    Masaharu Noda;Shin Shimizu;Tsutomu Tanabe;Toshiyuki Takai

  • Control of root system architecture by DEEPER ROOTING 1 increases rice yield under drought conditions

    Yusaku Uga;Kazuhiko Sugimoto;Satoshi Ogawa;Satoshi Ogawa;Jagadish Rane;Jagadish Rane

  • FcR γ chain deletion results in pleiotrophic effector cell defects

    Toshiyuki Takai;Min Li;Diana Sylvestre;Raphael Clynes

  • Molecular distinction between fetal and adult forms of muscle acetylcholine receptor

    Masayoshi Mishina;Toshiyuki Takai;Keiji Imoto;Masaharu Noda

  • Costimulatory signals mediated by the ITAM motif cooperate with RANKL for bone homeostasis

    Takako Koga;Masanori Inui;Kazuya Inoue;Sunhwa Kim

  • Augmented humoral and anaphylactic responses in FcγRII-deficient mice

    Toshiyuki Takai;Masao Ono;Masaki Hikida;Hitoshi Ohmori

  • Roles of Fc receptors in autoimmunity.

    Toshiyuki Takai

  • Modulation of immune complex-induced inflammation in vivo by the coordinate expression of activation and inhibitory Fc receptors.

    Raphael Clynes;Jay S. Maizes;Rodolphe Guinamard;Masao Ono

  • The adaptor protein CARD9 is essential for the activation of myeloid cells through ITAM-associated and Toll-like receptors.

    Hiromitsu Hara;Chitose Ishihara;Arata Takeuchi;Takayuki Imanishi

  • Deletion of Fcγ Receptor IIB Renders H-2b Mice Susceptible to Collagen-induced Arthritis

    Takae Yuasa;Satoshi Kubo;Tadashi Yoshino;Azusa Ujike

  • Regulation of osteoclast differentiation and function by the CaMK-CREB pathway.

    Kojiro Sato;Ayako Suematsu;Tomoki Nakashima;Sayaka Takemoto-Kimura

  • Osteopetrosis and thalamic hypomyelinosis with synaptic degeneration in DAP12-deficient mice

    Tomonori Kaifu;Jin Nakahara;Masanori Inui;Kenichi Mishima

  • Fcgamma receptor IIB-deficient mice develop Goodpasture's syndrome upon immunization with type IV collagen: a novel murine model for autoimmune glomerular basement membrane disease.

    Akira Nakamura;Takae Yuasa;Azusa Ujike;Masao Ono

  • Tyrosine kinases Btk and Tec regulate osteoclast differentiation by linking RANK and ITAM signals.

    Masahiro Shinohara;Takako Koga;Kazuo Okamoto;Shinya Sakaguchi

  • Macrophage colony-stimulating factor induces the proliferation and survival of macrophages via a pathway involving DAP12 and beta-catenin.

    Karel Otero;Isaiah R Turnbull;Pietro Luigi Poliani;William Vermi

  • Fc Receptors and Their Role in Immune Regulation and Autoimmunity

    Toshiyuki Takai

  • Siglec-H is an IPC-specific receptor that modulates type I IFN secretion through DAP12

    Amanda L. Blasius;Marina Cella;Marina Cella;Jorge Maldonado;Jorge Maldonado;Toshiyuki Takai;Toshiyuki Takai

  • Role of acetylcholine receptor subunits in gating of the channel.

    Bert Sakmann;Christoph Methfessel;Masayoshi Mishina;Tomoyuki Takahashi;Tomoyuki Takahashi

  • Reexpression of RAG-1 and RAG-2 Genes in Activated Mature Mouse B cells

    Masaki Hikida;Masaharu Mori;Toshiyuki Takai;Ken Ichi Tomochika

  • Primary structure of sheep prostaglandin endoperoxide synthase deduced from cDNA sequence

    Chieko Yokoyama;Toshiyuki Takai;Tadashi Tanabe

  • Plexin-A1 and its interaction with DAP12 in immune responses and bone homeostasis.

    Noriko Takegahara;Hyota Takamatsu;Toshihiko Toyofuku;Tohru Tsujimura

  • Requirement of SH2-containing Protein Tyrosine Phosphatases SHP-1 and SHP-2 for Paired Immunoglobulin-like Receptor B (PIR-B)–mediated Inhibitory Signal

    Akito Maeda;Mari Kurosaki;Masao Ono;Toshiyuki Takai

  • Molecular Cloning of a Novel Murine Cell-surface Glycoprotein Homologous to Killer Cell Inhibitory Receptors

    Keiko Hayami;Daisuke Fukuta;Yasuhiro Nishikawa;Yumi Yamashita

  • Impaired dendritic cell maturation and increased T H 2 responses in PIR-B −/− mice

    Azusa Ujike;Kazuhiko Takeda;Akira Nakamura;Shin Ebihara

Frequent Co-Authors

Motohiko Kondo
Motohiko Kondo Nagoya University
Marco Colonna
Marco Colonna Washington University in St. Louis
Tadashi Tanabe
Tadashi Tanabe University of Tokushima
Jeffrey V. Ravetch
Jeffrey V. Ravetch Rockefeller University
Masahiro Yano
Masahiro Yano National Agriculture and Food Research Organization
Toshihiro Nukiwa
Toshihiro Nukiwa Tohoku University
Hiroshi Takayanagi
Hiroshi Takayanagi University of Tokyo
Toshio Kitamura
Toshio Kitamura University of Tokyo
Yusaku Uga
Yusaku Uga Institute of Crop Science
Toshihide Yamashita
Toshihide Yamashita Osaka University

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Related Online Degrees & Career Pathways

For those interested in Immunology, exploring related online degrees can expand career opportunities in healthcare and research fields. Many professionals begin by enrolling in online RN programs for non nurses, which offer flexible pathways for individuals without a prior nursing background to enter the nursing profession.

After earning an RN, advancing to specialized roles such as Family Nurse Practitioner (FNP) can be accelerated through accelerated FNP programs. These programs prepare students quickly for certification and practice in primary care settings, often aligning with immunological expertise in patient care.

For nurses seeking to focus on critical care, obtaining an acute care nurse practitioner certification is a vital step. This credential enables practitioners to manage complex cases, many of which involve immune system disorders and immunotherapy treatments.

Understanding the financial outlook is also essential. Salaries can vary widely depending on location and credentials, so reviewing the DNP salary by state can help prospective students and professionals make informed career decisions in Immunology-related nursing fields across the USA.

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