Hajime Karasuyama

Overview

Best Publications

• Decreased apoptosis in the brain and premature lethality in CPP32-deficient mice

  Keisuke Kuida;Timothy S. Zheng;Songqing Na;Chia-Yi Kuan

  2390
  Citations

• Reduced Apoptosis and Cytochrome c-Mediated Caspase Activation in Mice Lacking Caspase 9

  Keisuke Kuida;Tarik F Haydar;Chia-Yi Kuan;Yong Gu

  2067
  Citations

• Establishment of mouse cell lines which constitutively secrete large quantities of interleukin 2, 3, 4 or 5, using modified cDNA expression vectors

  Hajime Karasuyama;Fritz Melchers

  1587
  Citations

• Interleukin-2 production by tumor cells bypasses T helper function in the generation of an antitumor response

  Eric R. Fearon;Drew M. Pardoll;Toshiuki Itaya;Paul Golumbek

  1268
  Citations

• Dominant-negative mutations in the DNA-binding domain of STAT3 cause hyper-IgE syndrome

  Yoshiyuki Minegishi;Masako Saito;Shigeru Tsuchiya;Ikuya Tsuge

  1204
  Citations

• Treatment of established renal cancer by tumor cells engineered to secrete interleukin-4

  Paul T. Golumbek;Audrey J. Lazenby;Hyam I. Levitsky;Liz M. Jaffee

  961
  Citations

• Human Tyrosine Kinase 2 Deficiency Reveals Its Requisite Roles in Multiple Cytokine Signals Involved in Innate and Acquired Immunity

  Yoshiyuki Minegishi;Masako Saito;Tomohiro Morio;Ken Watanabe

  804
  Citations

• The proteins encoded by the VpreB and lambda 5 pre-B cell-specific genes can associate with each other and with mu heavy chain.

  H Karasuyama;A Kudo;F Melchers

  507
  Citations

• Long-term proliferating early pre B cell lines and clones with the potential to develop to surface Ig-positive, mitogen reactive B cells in vitro and in vivo.

  A Rolink;A Kudo;H Karasuyama;Y Kikuchi

  445
  Citations

• Interleukin 7 receptor-deficient mice lack gammadelta T cells.

  Kazushige Maki;Shinji Sunaga;Yoshinori Komagata;Yuzo Kodaira

  435
  Citations

• Thymic stromal lymphopoietin–elicited basophil responses promote eosinophilic esophagitis

  Mario Noti;Elia D.Tait Wojno;Brian S. Kim;Mark C. Siracusa

  430
  Citations

• Basophils Play a Pivotal Role in Immunoglobulin-G-Mediated but Not Immunoglobulin-E-Mediated Systemic Anaphylaxis

  Yusuke Tsujimura;Kazushige Obata;Kaori Mukai;Hideo Shindou

  421
  Citations

• Essential role of Src-family protein tyrosine kinases in NF-kappaB activation during B cell development.

  Kaoru Saijo;Christian Schmedt;I-hsin Su;Hajime Karasuyama

  403
  Citations

• The surrogate light chain in B-cell development

  Fritz Melchers;Hajime Karasuyama;Dirk Haasner;Steven Bauer

  394
  Citations

• Basophils Play a Critical Role in the Development of IgE-Mediated Chronic Allergic Inflammation Independently of T Cells and Mast Cells

  Kaori Mukai;Kunie Matsuoka;Choji Taya;Hidenori Suzuki

  390
  Citations

• Basophils are essential initiators of a novel type of chronic allergic inflammation.

  Kazushige Obata;Kaori Mukai;Yusuke Tsujimura;Kenji Ishiwata

  363
  Citations

• IL-2 receptor alpha chain (CD25, TAC) expression defines a crucial stage in pre-B cell development.

  Antonius Rolink;Ulf Grawunder;Thomas H. Winkler;Hajime Karasuyama

  362
  Citations

• The expression of Vpre-B/λ5 surrogate light chain in early bone marrow precursor B cells of normal and B cell-deficient mutant mice

  Hajime Karasuyama;Antonius Rolink;Yoichi Shinkal;Faith Young

  354
  Citations

• Mouse and human neutrophils induce anaphylaxis.

  Friederike Jönsson;David A. Mancardi;Yoshihiro Kita;Hajime Karasuyama

  337
  Citations

• Selective ablation of basophils in mice reveals their nonredundant role in acquired immunity against ticks

  Takeshi Wada;Kenji Ishiwata;Haruhiko Koseki;Tomoyuki Ishikura

  337
  Citations

• Molecular explanation for the contradiction between systemic Th17 defect and localized bacterial infection in hyper-IgE syndrome

  Yoshiyuki Minegishi;Masako Saito;Masayuki Nagasawa;Hidetoshi Takada

  326
  Citations