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Immunology

D-Index
126
Citations
54490
World Ranking
274
National Ranking
177

Medicine

D-Index
126
Citations
54490
World Ranking
2976
National Ranking
1647

Research.com Recognitions

  • 2003 - Fellow of the American Association for the Advancement of Science (AAAS)
  • Member of the Association of American Physicians
  • Member of the Association of American Physicians
  • Member of the Association of American Physicians
  • Member of the Association of American Physicians

Overview

Fred D. Finkelman is affiliated with the University of Cincinnati in the United States and has contributed extensively to the fields of Medicine and Immunology and Microbiology. Their research focuses particularly on immunology, immunology and allergy, molecular biology, physiology, and radiology, nuclear medicine, and imaging.

The scientist's work addresses a variety of topics, including:

  • Food Allergy and Anaphylaxis Research
  • Mast Cells and Histamine
  • Immune Cell Function and Interaction
  • Asthma and Respiratory Diseases
  • Monoclonal and Polyclonal Antibodies Research
  • IL-33, ST2, and ILC Pathways
  • T-cell and B-cell Immunology

Fred D. Finkelman has published research in multiple peer-reviewed journals with notable frequency in the following venues:

  • Journal of Allergy and Clinical Immunology
  • The Journal of Immunology
  • Immunity
  • Frontiers in Immunology
  • bioRxiv (Cold Spring Harbor Laboratory)

Recent papers authored by or involving Finkelman include:

  • Microbiota-derived butyrate restricts tuft cell differentiation via histone deacetylase 3 to modulate intestinal type 2 immunity (2024, Immunity)
  • Ezh2-mediated epigenetic modification is required for allogeneic T cell-induced lupus disease (2020, Arthritis Research & Therapy)
  • The Akt-mTORC1 pathway mediates Axl receptor tyrosine kinase-induced mesangial cell proliferation (2021, Journal of Leukocyte Biology)
  • Mucosal Nanoemulsion Allergy Vaccine Suppresses Alarmin Expression and Induces Bystander Suppression of Reactivity to Multiple Food Allergens (2021, Frontiers in Immunology)
  • B-cell receptor physical properties affect relative IgG1 and IgE responses in mouse egg allergy (2022, Mucosal Immunology)

Frequent collaborators in their research efforts include:

  • Crystal Potter
  • Marat Khodoun
  • Suzanne C. Morris
  • Emily M. Eshleman
  • Taylor Rice

Fred D. Finkelman has been recognized by peers through membership and fellowship distinctions, including:

  • Fellow of the American Association for the Advancement of Science (AAAS), 2003
  • Member of the Association of American Physicians

Best Publications

  • Lymphokine control of in vivo immunoglobulin isotype selection.

    Finkelman Fd;Holmes J;Katona Im;Urban Jf

  • Local Macrophage Proliferation, Rather than Recruitment from the Blood, Is a Signature of TH2 Inflammation

    Stephen J. Jenkins;Dominik Ruckerl;Peter C. Cook;Lucy H. Jones

  • Generation of interleukin 4 (IL-4)-producing cells in vivo and in vitro: IL-2 and IL-4 are required for in vitro generation of IL-4-producing cells.

    G Le Gros;S Z Ben-Sasson;R Seder;F D Finkelman

  • The role of helper T cell products in mouse B cell differentiation and isotype regulation.

    Robert L. Coffman;Brian W. P. Seymour;Deborah A. Lebman;Debra D. Hiraki

  • IFN-gamma regulates the isotypes of Ig secreted during in vivo humoral immune responses.

    F D Finkelman;I M Katona;T R Mosmann;R L Coffman

  • CYTOKINE REGULATION OF HOST DEFENSE AGAINST PARASITIC GASTROINTESTINAL NEMATODES: Lessons from Studies with Rodent Models

    Fred D. Finkelman;Terez Shea-Donohue;Jon Goldhill;Carolyn A. Sullivan

  • IL-4 is required to generate and sustain in vivo IgE responses.

    F D Finkelman;I M Katona;J F Urban;J Holmes

  • Interleukin 12 inhibits antigen-induced airway hyperresponsiveness, inflammation, and Th2 cytokine expression in mice.

    Stephen H. Gavett;Daniel J. O’Hearn;Xiumin Li;Shau Ku Huang

  • IL-13, IL-4Rα, and Stat6 Are Required for the Expulsion of the Gastrointestinal Nematode Parasite Nippostrongylus brasiliensis

    Joseph F Urban;Nancy Noben-Trauth;Debra D Donaldson;Kathleen B Madden

  • Depletion of murine CD4+ T lymphocytes prevents antigen-induced airway hyperreactivity and pulmonary eosinophilia.

    S. H. Gavett;Xiaoling Chen;F. Finkelman;M. Wills-Karp

  • Interleukin-4- and interleukin-13-mediated host protection against intestinal nematode parasites.

    Fred D. Finkelman;Fred D. Finkelman;Terez Shea‐Donohue;Suzanne C. Morris;Lucy Gildea

  • Anaphylaxis: lessons from mouse models.

    Fred D. Finkelman

  • Basophils Produce IL-4 and Accumulate in Tissues after Infection with a Th2-inducing Parasite

    Booki Min;Melanie Prout;Jane Hu-Li;Jinfang Zhu

  • Cytokine-mediated regulation of chronic intestinal helminth infection.

    K J Else;F D Finkelman;C R Maliszewski;R K Grencis

  • Anti-cytokine antibodies as carrier proteins. Prolongation of in vivo effects of exogenous cytokines by injection of cytokine-anti-cytokine antibody complexes.

    F D Finkelman;K B Madden;S C Morris;J M Holmes

  • Anti-inflammatory activity of IgG1 mediated by Fc galactosylation and association of FcγRIIB and dectin-1

    Christian M. Karsten;Manoj K. Pandey;Julia Figge;Regina Kilchenstein

  • Differential regulation of IgG1 and IgE synthesis by interleukin 4.

    C M Snapper;F D Finkelman;W E Paul

  • Immunoglobulin signal transduction guides the specificity of B cell-T cell interactions and is blocked in tolerant self-reactive B cells.

    Michael P. Cooke;Andrew W. Heath;Kevan M. Shokat;Yongjun Zeng

  • Evidence for the involvement of interleukin 10 in the differential deactivation of murine peritoneal macrophages by prostaglandin E2.

    G. Strassmann;Vina Patil-Koota;F. Finkelman;Miranda Fong

  • Interleukin 4 is important in protective immunity to a gastrointestinal nematode infection in mice.

    J F Urban;I M Katona;W E Paul;F D Finkelman

Frequent Co-Authors

Suzanne C. Morris
Suzanne C. Morris University of Cincinnati Medical Center
Joseph F. Urban
Joseph F. Urban United States Department of Agriculture
James J. Mond
James J. Mond Uniformed Services University of the Health Sciences
Irwin Scher
Irwin Scher OperTechBio
Marc E. Rothenberg
Marc E. Rothenberg Cincinnati Children's Hospital Medical Center
William C. Gause
William C. Gause Rutgers, The State University of New Jersey
Simon P. Hogan
Simon P. Hogan Cincinnati Children's Hospital Medical Center
William E. Paul
William E. Paul National Institute of Allergy and Infectious Diseases
Marsha Wills-Karp
Marsha Wills-Karp Johns Hopkins University
John J. Ryan
John J. Ryan Virginia Commonwealth University

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