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Immunology
South Africa
2022

D-Index & Metrics

Immunology

D-Index
92
Citations
38955
World Ranking
994
National Ranking
5

Medicine

D-Index
92
Citations
38982
World Ranking
11144
National Ranking
23

Research.com Recognitions

  • 2022 - Research.com Immunology in South Africa Leader Award

Overview

Frank Brombacher is affiliated with the University of Cape Town in South Africa. Their research primarily spans the fields of Medicine and Immunology and Microbiology, with significant contributions to subfields such as Immunology, Epidemiology, Molecular Biology, Parasitology, and Physiology.

Their work addresses several main topics, including:

  • IL-33, ST2, and ILC Pathways
  • Immune Cell Function and Interaction
  • Parasites and Host Interactions
  • Asthma and respiratory diseases
  • Research on Leishmaniasis Studies
  • Mycobacterium research and diagnosis
  • Tuberculosis Research and Epidemiology

Frank Brombacher has published extensively in various scientific venues. The most frequent publication venues include:

  • Frontiers in Immunology
  • Scientific Reports
  • Journal of Allergy and Clinical Immunology
  • bioRxiv (Cold Spring Harbor Laboratory)
  • Genome Research

Some of their recent papers are:

  • Functional annotation of human long noncoding RNAs via molecular phenotyping, 2020, Genome Research
  • Homeostatic IL-13 in healthy skin directs dendritic cell differentiation to promote TH2 and inhibit TH17 cell polarization, 2021, Nature Immunology
  • Investigating the antifibrotic effect of the antiparasitic drug Praziquantel in in vitro and in vivo preclinical models, 2020, Scientific Reports
  • Immunoglobulin M in Health and Diseases: How Far Have We Come and What Next?, 2020, Frontiers in Immunology
  • Targeting Molecular Inflammatory Pathways in Granuloma as Host-Directed Therapies for Tuberculosis, 2021, Frontiers in Immunology

Frequent co-authors who have collaborated with Frank Brombacher include:

  • Mumin Ozturk
  • Suraj P. Parihar
  • Reto Guler
  • Sabelo Hadebe
  • Justin Komguep Nono

Best Publications

  • Requirement for IL-13 independently of IL-4 in experimental asthma

    G. Grünig;M. Warnock;A. E. Wakil;R. Venkayya

  • Macrophage-specific PPARγ controls alternative activation and improves insulin resistance

    Justin I. Odegaard;Roberto R. Ricardo-Gonzalez;Matthew H. Goforth;Christine R. Morel

  • A promoter-level mammalian expression atlas

    Alistair R.R. Forrest;Hideya Kawaji;Michael Rehli;J. Kenneth Baillie

  • Alternatively activated macrophages produce catecholamines to sustain adaptive thermogenesis

    Khoa D. Nguyen;Yifu Qiu;Xiaojin Cui;Y. P. Sharon Goh;Y. P. Sharon Goh

  • Control of early viral and bacterial distribution and disease by natural antibodies.

    Adrian F. Ochsenbein;Thomas Fehr;Claudia Lutz;Mark Suter

  • Sensory Neurons Co-opt Classical Immune Signaling Pathways to Mediate Chronic Itch

    Landon K. Oetjen;Madison R. Mack;Jing Feng;Timothy M. Whelan

  • Tumors induce a subset of inflammatory monocytes with immunosuppressive activity on CD8+ T cells

    Giovanna Gallina;Luigi Dolcetti;Paolo Serafini;Carmela De Santo

  • Alternative macrophage activation is essential for survival during schistosomiasis and downmodulates T helper 1 responses and immunopathology.

    De'Broski R Herbert;Christoph Hölscher;Markus Mohrs;Berenice Arendse

  • Interleukin-17 is a negative regulator of established allergic asthma

    Silvia Schnyder-Candrian;Dieudonnée Togbe;Isabelle Couillin;Isabelle Mercier

  • IL-5-Deficient Mice Have a Developmental Defect in CD5+ B-1 Cells and Lack Eosinophilia but Have Normal Antibody and Cytotoxic T Cell Responses

    Manfred Kopf;Frank Brombacher;Philip D Hodgkin;Alistair J Ramsay

  • Transcribed enhancers lead waves of coordinated transcription in transitioning mammalian cells

    Erik Arner;Carsten O. Daub;Kristoffer Vitting-Seerup;Robin Andersson

  • Differential expression of FIZZ1 and Ym1 in alternatively versus classically activated macrophages

    Geert Raes;Patrick De Baetselier;Wim Noël;Alain Beschin

  • Aluminium Hydroxide Adjuvant Initiates Strong Antigen-Specific Th2 Responses in the Absence of IL-4- or IL-13-Mediated Signaling

    James M. Brewer;Margaret Conacher;Christopher A. Hunter;Markus Mohrs

  • IL-25 regulates Th17 function in autoimmune inflammation

    Melanie A. Kleinschek;Alexander M. Owyang;Barbara Joyce-Shaikh;Claire L. Langrish

  • The transcriptional network that controls growth arrest and differentiation in a human myeloid leukemia cell line

    Harukazu Suzuki;Alistair R.R. Forrest;Erik Van Nimwegen;Carsten O. Daub

  • IL-4 directly signals tissue-resident macrophages to proliferate beyond homeostatic levels controlled by CSF-1

    Stephen J. Jenkins;Dominik Ruckerl;Graham D. Thomas;James P. Hewitson

  • An interleukin 4 (IL-4)-independent pathway for CD4+ T cell IL-4 production is revealed in IL-4 receptor-deficient mice

    Nancy Noben-Trauth;Leonard D. Shultz;Frank Brombacher;Joseph F. Urban

  • Novel IL-12 family members shed light on the orchestration of Th1 responses.

    Frank Brombacher;Robert A. Kastelein;Gottfried Alber

  • Differences between IL-4- and IL-4 receptor alpha-deficient mice in chronic leishmaniasis reveal a protective role for IL-13 receptor signaling.

    Markus Mohrs;Birgit Ledermann;Gabriele Köhler;Andreas Dorfmüller

  • Distinct bone marrow-derived and tissue-resident macrophage lineages proliferate at key stages during inflammation

    Luke Cynlais Davies;Marcela Rosas;Stephen J. Jenkins;Chia-Te Liao

  • Alternative macrophage activation is essential for survival during schistosomiasis and downmodulates T helper 1 responses and immunopathology (vol 20, pg 623, 2004)

    D. R. Herbert;C. Holscher;M. Mohrs;B. Arendse

Frequent Co-Authors

Stefan Magez
Stefan Magez Ghent University
Gordon D. Brown
Gordon D. Brown University of Exeter
Markus Mohrs
Markus Mohrs Trudeau Institute
James Alexander
James Alexander Centers for Disease Control and Prevention
Patrick De Baetselier
Patrick De Baetselier Vrije Universiteit Brussel
Alistair R. R. Forrest
Alistair R. R. Forrest Harry Perkins Institute of Medical Research
Gabriele Köhler
Gabriele Köhler University of Münster

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