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Immunology

D-Index
50
Citations
15620
World Ranking
4188
National Ranking
1910

Overview

Markus Mohrs is affiliated with the Trudeau Institute in the United States. Their research primarily spans the fields of Immunology and Microbiology, Medicine, and Biochemistry, Genetics and Molecular Biology. Within these broader areas, their work focuses notably on Immunology, Oncology, Surgery, Molecular Biology, and Cancer Research.

Their research topics encompass several specialized subjects, including:

  • IL-33, ST2, and ILC Pathways
  • Eosinophilic Esophagitis
  • CAR-T cell therapy research
  • Single-cell and spatial transcriptomics
  • Immune cells in cancer
  • Cancer Genomics and Diagnostics
  • Galectins and Cancer Biology

Markus Mohrs has contributed to multiple publications, with recent papers covering a range of immunological and oncological topics. These include:

  • "Heterogeneity and chimerism of endothelial cells revealed by single-cell transcriptome in orthotopic liver tumors," 2020, published in Angiogenesis
  • "Campylobacter infection promotes IFNγ-dependent intestinal pathology via ILC3 to ILC1 conversion," 2020, published in Mucosal Immunology
  • "Human CD4 cytotoxic T lymphocytes mediate potent tumor control in humanized immune system mice," 2023, published in Communications Biology
  • "Correction to: Campylobacter infection promotes IFNγ-dependent intestinal pathology via ILC3 to ILC1 conversion," 2021, published in Mucosal Immunology
  • "851 Voyager V1 (VV1) oncolytic virus combined with immune checkpoint therapy boosts CTL responses to multiple tumor antigens and correspondingly deepens tumor responses in murine models of melanoma, lung and colon cancer," 2022, published in Regular and Young Investigator Award Abstracts

Mohrs frequently collaborates with several researchers, including Gavin Thurston, Wayne T. Muraoka, Anna А. Korchagina, Qingqing Xia, and Sergey A. Shein. The majority of their joint work appears in journals such as Mucosal Immunology, Angiogenesis, Communications Biology, and abstract compilations like Regular and Young Investigator Award Abstracts.

Best Publications

  • Requirement for IL-13 independently of IL-4 in experimental asthma

    G. Grünig;M. Warnock;A. E. Wakil;R. Venkayya

  • Alternative macrophage activation is essential for survival during schistosomiasis and downmodulates T helper 1 responses and immunopathology.

    De'Broski R Herbert;Christoph Hölscher;Markus Mohrs;Berenice Arendse

  • Constitutive Cytokine mRNAs Mark Natural Killer (NK) and NK T Cells Poised for Rapid Effector Function

    Daniel B. Stetson;Markus Mohrs;R. Lee Reinhardt;Jody L. Baron

  • Analysis of type 2 immunity in vivo with a bicistronic IL-4 reporter.

    Markus Mohrs;Kanade Shinkai;Katja Mohrs;Richard M Locksley

  • Early transcription and silencing of cytokine genes underlie polarization of T helper cell subsets.

    Jane L. Grogan;Markus Mohrs;Brian Harmon;Dee A. Lacy

  • Aluminium Hydroxide Adjuvant Initiates Strong Antigen-Specific Th2 Responses in the Absence of IL-4- or IL-13-Mediated Signaling

    James M. Brewer;Margaret Conacher;Christopher A. Hunter;Markus Mohrs

  • T follicular helper cells differentiate from Th2 cells in response to helminth antigens

    Arielle Glatman Zaretsky;Justin J. Taylor;Irah L. King;Fraser A. Marshall

  • IL-4 producing CD4+ T cells in reactive lymph nodes during helminth infection are T follicular helper cells

    Irah L. King;Markus Mohrs

  • Omega-1, a glycoprotein secreted by Schistosoma mansoni eggs, drives Th2 responses.

    Bart Everts;Georgia Perona-Wright;Hermelijn H. Smits;Cornelis H. Hokke

  • Mast Cells, Basophils, and Eosinophils Acquire Constitutive IL-4 and IL-13 Transcripts during Lineage Differentiation That Are Sufficient for Rapid Cytokine Production

    André Gessner;Katja Mohrs;Markus Mohrs

  • Differences between IL-4- and IL-4 receptor alpha-deficient mice in chronic leishmaniasis reveal a protective role for IL-13 receptor signaling.

    Markus Mohrs;Birgit Ledermann;Gabriele Köhler;Andreas Dorfmüller

  • Th2-induced airway mucus production is dependent on IL-4Ralpha, but not on eosinophils.

    Lauren Cohn;Robert J. Homer;Heather MacLeod;Markus Mohrs

  • Alternative activation is an innate response to injury that requires CD4+ T cells to be sustained during chronic infection

    P'ng Loke;Iain Gallagher;Meera G Nair;Meera G Nair;Xingxing Zang

  • Nonredundant Roles for B Cell-Derived IL-10 in Immune Counter-Regulation

    Rajat Madan;Filiz Demircik;Sangeetha Surianarayanan;Jessica L. Allen

  • A Two-Step Process for Cytokine Production Revealed by IL-4 Dual-Reporter Mice

    Katja Mohrs;Adil E. Wakil;Nigel Killeen;Richard M. Locksley

  • Mouse Vα14i natural killer T cells are resistant to cytokine polarization in vivo

    Jennifer L. Matsuda;Laurent Gapin;Jody L. Baron;Stéphane Sidobre

  • Differences between IL-4Rα-deficient and IL-4-deficient mice reveal a role for IL-13 in the regulation of Th2 responses

    Marijke Barner;Markus Mohrs;Frank Brombacher;Manfred Kopf

  • Schistosome-derived omega-1 drives Th2 polarization by suppressing protein synthesis following internalization by the mannose receptor

    Bart Everts;Leonie Hussaarts;Nicole N. Driessen;Moniek H.J. Meevissen

  • Cytokine-producing effector B cells regulate type 2 immunity to H. polygyrus

    Wojciech Wojciechowski;David P. Harris;Frank Sprague;Betty Mousseau

  • Helper T cells regulate type-2 innate immunity in vivo

    Kanade Shinkai;Markus Mohrs;Richard M. Locksley

  • Alternative macrophage activation is essential for survival during schistosomiasis and downmodulates T helper 1 responses and immunopathology (vol 20, pg 623, 2004)

    D. R. Herbert;C. Holscher;M. Mohrs;B. Arendse

Frequent Co-Authors

Frank Brombacher
Frank Brombacher University of Cape Town
Richard M. Locksley
Richard M. Locksley University of California, San Francisco
Edward J. Pearce
Edward J. Pearce Johns Hopkins University
David L. Woodland
David L. Woodland Trudeau Institute
David Artis
David Artis Cornell University
Frances E. Lund
Frances E. Lund University of Alabama at Birmingham
Walter Sebald
Walter Sebald University of Würzburg
Albert Duschl
Albert Duschl University of Salzburg
Helmut L. Haas
Helmut L. Haas Heinrich Heine University Düsseldorf
Gurdyal S. Besra
Gurdyal S. Besra University of Birmingham

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