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Padraic G. Fallon

Padraic G. Fallon

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Immunology
Ireland
2026

D-Index & Metrics

Immunology

D-Index
93
Citations
33573
World Ranking
962
National Ranking
3

Medicine

D-Index
93
Citations
33645
World Ranking
10838
National Ranking
28

Research.com Recognitions

  • 2026 - Research.com Immunology in Ireland Leader Award
  • 2025 - Research.com Immunology in Ireland Leader Award
  • 2023 - Research.com Immunology in Ireland Leader Award
  • 2022 - Research.com Immunology in Ireland Leader Award
  • 2014 - Member of the Royal Irish Academy

Overview

Padraic G. Fallon is affiliated with Trinity College Dublin in Ireland and focuses on research primarily in the fields of Medicine and Immunology and Microbiology. Their work addresses several subfields including Immunology, Oncology, Physiology, Epidemiology, and Hematology.

The scientist's research covers a range of topics, notably:

  • Immune Cell Function and Interaction
  • IL-33, ST2, and ILC Pathways
  • Asthma and respiratory diseases
  • Dermatology and Skin Diseases
  • Immune cells in cancer
  • COVID-19 Clinical Research Studies
  • Eosinophilic Esophagitis

Among recent publications, selected papers include:

  • "Itaconate and itaconate derivatives target JAK1 to suppress alternative activation of macrophages" (2022, Cell Metabolism)
  • "Tumor PD-L1 engages myeloid PD-1 to suppress type I interferon to impair cytotoxic T lymphocyte recruitment" (2023, Cancer Cell)
  • "When killers become thieves: Trogocytosed PD-1 inhibits NK cells in cancer" (2022, Science Advances)
  • "SREBP1-induced fatty acid synthesis depletes macrophages antioxidant defences to promote their alternative activation" (2021, Nature Metabolism)
  • "von Willebrand factor links primary hemostasis to innate immunity" (2022, Nature Communications)

Frequent co-authors collaborating with Padraic G. Fallon include:

  • Heike C. Hawerkamp
  • Emily Hams
  • Roger J. S. Preston
  • Clíona Ní Cheallaigh
  • Niall Conlon

The scientist publishes regularly in a set of venues, with multiple contributions to:

  • Frontiers in Immunology
  • The Journal of Immunology
  • bioRxiv (Cold Spring Harbor Laboratory)
  • Nature Communications
  • Faculty Opinions - Post-Publication Peer Review of the Biomedical Literature

The academic record of Padraic G. Fallon includes receiving the distinction of Member of the Royal Irish Academy in 2014.

Best Publications

  • Nuocytes represent a new innate effector leukocyte that mediates type-2 immunity

    Daniel R. Neill;See Heng Wong;Agustin Bellosi;Robin J. Flynn

  • Itaconate is an anti-inflammatory metabolite that activates Nrf2 via alkylation of KEAP1.

    Evanna L Mills;Dylan G Ryan;Hiran A Prag;Dina Dikovskaya

  • The alarmin IL-33 promotes regulatory T-cell function in the intestine

    Chris Schiering;Thomas Krausgruber;Agnieszka Chomka;Anja Fröhlich

  • A role for IL-25 and IL-33-driven type-2 innate lymphoid cells in atopic dermatitis.

    Maryam Salimi;Jillian L. Barlow;Sean P. Saunders;Luzheng Xue

  • Identification of an interleukin (IL)-25–dependent cell population that provides IL-4, IL-5, and IL-13 at the onset of helminth expulsion

    Padraic G. Fallon;Sarah J. Ballantyne;Niamh E. Mangan;Jillian L. Barlow

  • MHCII-Mediated Dialog between Group 2 Innate Lymphoid Cells and CD4+ T Cells Potentiates Type 2 Immunity and Promotes Parasitic Helminth Expulsion

    Christopher J. Oliphant;You Yi Hwang;Jennifer A. Walker;Maryam Salimi

  • Transcription factor RORα is critical for nuocyte development

    See Heng Wong;See Heng Wong;Jennifer A Walker;Helen E Jolin;Lesley F Drynan

  • Drug-resistant schistosomiasis: resistance to praziquantel and oxamniquine induced in Schistosoma mansoni in mice is drug specific

    Padraic G. Fallon;Michael J. Doenhoff

  • T1/St2-Deficient Mice Demonstrate the Importance of T1/St2 in Developing Primary T Helper Cell Type 2 Responses

    Michael J. Townsend;Padraic G. Fallon;David J. Matthews;Helen E. Jolin

  • Schistosome Infection of Transgenic Mice Defines Distinct and Contrasting Pathogenic Roles for IL-4 and IL-13: IL-13 Is a Profibrotic Agent

    Padraic G. Fallon;Emma J. Richardson;Grahame J. McKenzie;Andrew N. J. McKenzie

  • A homozygous frameshift mutation in the mouse Flg gene facilitates enhanced percutaneous allergen priming

    Padraic G Fallon;Takashi Sasaki;Aileen Sandilands;Linda E Campbell

  • The Alarmin Interleukin-33 Drives Protective Antiviral CD8+ T Cell Responses

    Weldy V. Bonilla;Anja Fröhlich;Anja Fröhlich;Karin Senn;Sandra Kallert

  • The Hydroxylase Inhibitor Dimethyloxalylglycine Is Protective in a Murine Model of Colitis

    Eoin P. Cummins;Fergal Seeballuck;Stephen J. Keely;Niamh E. Mangan

  • Impaired Development of Th2 Cells in IL-13-Deficient Mice

    Grahame J McKenzie;Claire L Emson;Sarah E Bell;Shannon Anderson

  • Regulatory B cells prevent and reverse allergic airway inflammation via FoxP3-positive T regulatory cells in a murine model

    Sylvie Amu;Sean P. Saunders;Mitchell Kronenberg;Niamh E. Mangan

  • IL-4 Induces Characteristic Th2 Responses Even in the Combined Absence of IL-5, IL-9, and IL-13

    Padraic G. Fallon;Helen E. Jolin;Philippa Smith;Claire L. Emson

  • Simultaneous disruption of interleukin (IL)-4 and IL-13 defines individual roles in T helper cell type 2-mediated responses.

    Grahame J. McKenzie;Padraic G. Fallon;Claire L. Emson;Richard K. Grencis

  • IL-25 and type 2 innate lymphoid cells induce pulmonary fibrosis

    Emily Hams;Michelle E. Armstrong;Michelle E. Armstrong;Jillian L. Barlow;Sean P. Saunders;Sean P. Saunders

  • IL-9-deficient mice establish fundamental roles for IL-9 in pulmonary mastocytosis and goblet cell hyperplasia but not T cell development.

    Michael J Townsend;Padraic G Fallon;David J Matthews;Philip Smith

  • Skin microbiome before development of atopic dermatitis: Early colonization with commensal staphylococci at 2 months is associated with a lower risk of atopic dermatitis at 1 year.

    Elizabeth A. Kennedy;Jennifer Connolly;Jonathan O'b. Hourihane;Padraic G. Fallon;Padraic G. Fallon

Frequent Co-Authors

Andrew N. J. McKenzie
Andrew N. J. McKenzie MRC Laboratory of Molecular Biology
Alan D. Irvine
Alan D. Irvine Trinity College Dublin
Michael J. Doenhoff
Michael J. Doenhoff University of Nottingham
Adrien Kissenpfennig
Adrien Kissenpfennig Queen's University Belfast
Antonio Alcami
Antonio Alcami Spanish National Research Council
David W. Dunne
David W. Dunne University of Cambridge
Cormac T. Taylor
Cormac T. Taylor University College Dublin
Graham S. Ogg
Graham S. Ogg University of Oxford
Andrew Alderson
Andrew Alderson Sheffield Hallam University

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