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Biology and Biochemistry

D-Index
72
Citations
18543
World Ranking
6302
National Ranking
483

Overview

Thomas Krieg is a researcher affiliated with the University of Cambridge in the United Kingdom. Their work spans multiple fields, predominantly in medicine and biochemistry, genetics, and molecular biology. The main subfields of their research include molecular biology, pathology and forensic medicine, cardiology and cardiovascular medicine, physiology, and neurology.

Their research focuses extensively on several core topics in biomedical science. These include mitochondrial function and pathology, cardiac ischemia and reperfusion, cardiovascular function and risk factors, cardiac arrest and resuscitation, ATP synthase and ATPases research, cardiac electrophysiology and arrhythmias, and diet and metabolism studies.

Thomas Krieg has published multiple papers in high-profile journals, covering advancements in cardiovascular and molecular biology research. Some of the recent papers include:

  • Cardiac metabolism as a driver and therapeutic target of myocardial infarction, 2020, Journal of Cellular and Molecular Medicine
  • Long COVID and the cardiovascular system-elucidating causes and cellular mechanisms in order to develop targeted diagnostic and therapeutic strategies: a joint Scientific Statement of the ESC Working Groups on Cellular Biology of the Heart and Myocardial and Pericardial Diseases, 2022, Cardiovascular Research
  • Structural basis for a complex I mutation that blocks pathological ROS production, 2021, Nature Communications
  • Health position paper and redox perspectives on reactive oxygen species as signals and targets of cardioprotection, 2023, Redox Biology
  • Mechanism of succinate efflux upon reperfusion of the ischaemic heart, 2020, Cardiovascular Research

Frequent co-authors collaborating with Thomas Krieg include:

  • Michael P. Murphy
  • Hiran A. Prag
  • Richard C. Hartley
  • Andrew M. James
  • Nils Burger

Their research output is often published in these venues:

  • Redox Biology
  • Cardiovascular Research
  • Free Radical Biology and Medicine
  • Basic Research in Cardiology
  • Cardiovascular Drugs and Therapy

Best Publications

  • Ischaemic accumulation of succinate controls reperfusion injury through mitochondrial ROS.

    Edward T. Chouchani;Edward T. Chouchani;Victoria R. Pell;Edoardo Gaude;Dunja Aksentijević

  • Multiple, brief coronary occlusions during early reperfusion protect rabbit hearts by targeting cell signaling pathways

    Xi-Ming Yang;J. Bradley Proctor;Lin Cui;Thomas Krieg

  • Cardioprotection by S-nitrosation of a cysteine switch on mitochondrial complex I

    Edward T Chouchani;Carmen Methner;Sergiy M Nadtochiy;Angela Logan

  • A Unifying Mechanism for Mitochondrial Superoxide Production during Ischemia-Reperfusion Injury.

    Edward T. Chouchani;Victoria R. Pell;Andrew M. James;Lorraine M. Work

  • Recombinant nidogen consists of three globular domains and mediates binding of laminin to collagen type IV.

    J W Fox;U Mayer;R Nischt;M Aumailley

  • Enhanced expression levels of IL-31 correlate with IL-4 and IL-13 in atopic and allergic contact dermatitis

    Mark M. Neis;Bettina Peters;Alexandra Dreuw;Joerg Wenzel

  • Bradykinin induces mitochondrial ROS generation via NO, cGMP, PKG, and mitoKATP channel opening and leads to cardioprotection.

    Olaf Oldenburg;Qining Qin;Thomas Krieg;Xi-Ming Yang

  • Inhibition of skin development by overexpression of transforming growth factor beta 1 in the epidermis of transgenic mice

    Klaus Sellheyer;Jackie R. Bickenbach;Joseph A. Rothnagel;Donnie Bundman

  • European contribution to the study of ROS : a summary of the findings and prospects for the future from the COST action BM1203 (EU-ROS)

    Javier Egea;Isabel Fabregat;Yves M Frapart;Pietro Ghezzi

  • Transcriptional control of high molecular weight keratin gene expression in multistage mouse skin carcinogenesis.

    Dennis R. Roop;Thomas M. Krieg;Thomas Mehrel;Christina K. Cheng

  • Mitochondria-derived ROS activate AMP-activated protein kinase (AMPK) indirectly

    Elizabeth C Hinchy;Anja Gruszczyk;Robin Willows;Naveenan Navaratnam

  • Functional assessment and transplantation of the donor heart after circulatory death.

    Simon J. Messer;Richard G. Axell;Simon Colah;Paul A. White

  • EXTRACELLULAR-MATRIX COMPONENTS SYNTHESIZED BY HUMAN AMNIOTIC EPITHELIAL-CELLS IN CULTURE

    Kari Alitalo;Markku Kurkinen;Antti Vaheri;Thomas Krieg

  • New developments in fibroblast and myofibroblast biology: Implications for fibrosis and scleroderma

    David J. Abraham;Beate Eckes;Vineeth Rajkumar;Thomas Krieg

  • Toll-like receptor-4 deficiency attenuates doxorubicin-induced cardiomyopathy in mice.

    Alexander Riad;Sandra Bien;Matthias Gratz;Felicitas Escher

  • The absence of nidogen 1 does not affect murine basement membrane formation.

    Monzur Murshed;Neil Smyth;Nicolai Miosge;Jörg Karolat

  • NECA and bradykinin at reperfusion reduce infarction in rabbit hearts by signaling through PI3K, ERK, and NO.

    Xi-Ming Yang;Thomas Krieg;Lin Cui;James M Downey

  • Expression of a dominant-negative type II transforming growth factor β (TGF-β) receptor in the epidermis of transgenic mice blocks TGF-β-mediated growth inhibition

    Xiao-Jing Wang;David A. Greenhalgh;Jackie R. Bickenbach;Aibo Jiang

  • Merkel cell polyomavirus DNA in persons without merkel cell carcinoma.

    Ulrike Wieland;Cornelia Mauch;Alexander Kreuter;Thomas Krieg

  • Erythroplasia of Queyrat: Coinfection with Cutaneous Carcinogenic Human Papillomavirus Type 8 and Genital Papillomaviruses in a Carcinoma In Situ

    Ulrike Wieland;Sandra Jurk;Sönke Weißenborn;Herbert Pfister

Frequent Co-Authors

Michael P. Murphy
Michael P. Murphy University of Cambridge
James M. Downey
James M. Downey University of South Alabama
Michael V. Cohen
Michael V. Cohen University of South Alabama
Andrew M. James
Andrew M. James MRC Mitochondrial Biology Unit
Christian Frezza
Christian Frezza University of Cambridge
Margitta Worm
Margitta Worm Charité - University Medicine Berlin
Heyo K. Kroemer
Heyo K. Kroemer University of Göttingen
Rupert Timpl
Rupert Timpl Max Planck Society
Beate Eckes
Beate Eckes University of Cologne

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