D-Index & Metrics Best Publications

D-Index & Metrics D-index (Discipline H-index) only includes papers and citation values for an examined discipline in contrast to General H-index which accounts for publications across all disciplines.

Discipline name D-index D-index (Discipline H-index) only includes papers and citation values for an examined discipline in contrast to General H-index which accounts for publications across all disciplines. Citations Publications World Ranking National Ranking
Biology and Biochemistry D-index 59 Citations 27,864 119 World Ranking 5857 National Ranking 458

Overview

What is he best known for?

The fields of study he is best known for:

  • Gene
  • Enzyme
  • Cancer

The scientist’s investigation covers issues in Mitochondrion, Biochemistry, Cell biology, Citric acid cycle and Downregulation and upregulation. His biological study spans a wide range of topics, including Cancer cell, Cancer and Anaerobic glycolysis. Christian Frezza works mostly in the field of Cancer cell, limiting it down to topics relating to Pathogenesis and, in certain cases, Carcinogenesis, as a part of the same area of interest.

His work in Cell biology covers topics such as Optic Atrophy 1 which are related to areas like Mitochondrial apoptosis-induced channel. His Downregulation and upregulation study integrates concerns from other disciplines, such as Cell growth and Bioinformatics. His research in Oxidative phosphorylation intersects with topics in Glycolysis and Signal transduction.

His most cited work include:

  • Guidelines for the use and interpretation of assays for monitoring autophagy (3rd edition) (4170 citations)
  • Succinate is an inflammatory signal that induces IL-1β through HIF-1α (1591 citations)
  • OPA1 Controls Apoptotic Cristae Remodeling Independently from Mitochondrial Fusion (1116 citations)

What are the main themes of his work throughout his whole career to date?

His primary areas of study are Cell biology, Mitochondrion, Cancer research, Biochemistry and Cancer. The concepts of his Cell biology study are interwoven with issues in Metabolic pathway and Metabolism. Christian Frezza has researched Mitochondrion in several fields, including Reactive oxygen species, Oxidative phosphorylation, Organelle and Citric acid cycle.

His Cancer research research is multidisciplinary, relying on both Epithelial–mesenchymal transition, Downregulation and upregulation, Cell, Fumarase and Renal cell carcinoma. Programmed cell death, Serine, Transcription factor, Enzyme activator and Metabolite are the primary areas of interest in his Biochemistry study. His work in Cancer addresses subjects such as Cell growth, which are connected to disciplines such as Respiratory chain.

He most often published in these fields:

  • Cell biology (35.19%)
  • Mitochondrion (31.48%)
  • Cancer research (25.31%)

What were the highlights of his more recent work (between 2019-2021)?

  • Mitochondrion (31.48%)
  • Cell biology (35.19%)
  • Cancer research (25.31%)

In recent papers he was focusing on the following fields of study:

Christian Frezza spends much of his time researching Mitochondrion, Cell biology, Cancer research, Cancer and Metabolism. His Mitochondrion research includes elements of Citric acid cycle, Proteomics, Central nervous system, Organelle and Transplantation. His Cell biology research is multidisciplinary, relying on both Metabolite and Transcription factor.

His research in Cancer research intersects with topics in Transcriptome, Downregulation and upregulation, Cytokine secretion, IκB kinase and Kinase. His studies in Cancer integrate themes in fields like Genetic variants and Gene. In his study, Computational biology is strongly linked to METABOLIC FEATURES, which falls under the umbrella field of Cancer metabolism.

Between 2019 and 2021, his most popular works were:

  • Cancer associated fibroblast FAK regulates malignant cell metabolism. (23 citations)
  • Metabolism and cancer the future is now (21 citations)
  • Fumarate hydratase in cancer: A multifaceted tumour suppressor. (21 citations)

In his most recent research, the most cited papers focused on:

  • Gene
  • Enzyme
  • Cancer

Christian Frezza mainly investigates Cancer research, Cancer, Cancer cell, Carcinogenesis and Mitochondrion. His Cancer research research is multidisciplinary, incorporating perspectives in Cell culture and Haematopoiesis. His Cancer study integrates concerns from other disciplines, such as Phenotype, Renal cell carcinoma, Disease, Regulation of gene expression and Epigenetics.

His Cancer cell research incorporates themes from METABOLIC FEATURES, Cancer biology, Computational biology and Cellular Transformation. Christian Frezza has researched Carcinogenesis in several fields, including Isocitrate dehydrogenase, Suppressor, Reprogramming, Fumarase and Succinate dehydrogenase. In his work, Christian Frezza performs multidisciplinary research in Mitochondrion and Monocarboxylate transporter 1.

This overview was generated by a machine learning system which analysed the scientist’s body of work. If you have any feedback, you can contact us here.

Best Publications

Guidelines for the use and interpretation of assays for monitoring autophagy (3rd edition)

Daniel J. Klionsky;Kotb Abdelmohsen;Akihisa Abe;Joynal Abedin.
Autophagy (2016)

7788 Citations

Erratum to: Guidelines for the use and interpretation of assays for monitoring autophagy (3rd edition) (Autophagy, 12, 1, 1-222, 10.1080/15548627.2015.1100356

Daniel J. Klionsky;Kotb Abdelmohsen;Akihisa Abe;Joynal Abedin.
Autophagy (2016)

4781 Citations

Succinate is an inflammatory signal that induces IL-1β through HIF-1α

G. M. Tannahill;A. M. Curtis;J. Adamik;E. M. Palsson-McDermott.
Nature (2013)

1950 Citations

OPA1 Controls Apoptotic Cristae Remodeling Independently from Mitochondrial Fusion

Christian Frezza;Sara Cipolat;Olga Martins de Brito;Massimo Micaroni.
Cell (2006)

1423 Citations

Ischaemic accumulation of succinate controls reperfusion injury through mitochondrial ROS.

Edward T. Chouchani;Edward T. Chouchani;Victoria R. Pell;Edoardo Gaude;Dunja Aksentijević.
Nature (2014)

1375 Citations

Organelle isolation: functional mitochondria from mouse liver, muscle and cultured fibroblasts.

Christian Frezza;Sara Cipolat;Luca Scorrano.
Nature Protocols (2007)

999 Citations

Mitochondrial Cristae Shape Determines Respiratory Chain Supercomplexes Assembly and Respiratory Efficiency

Sara Cogliati;Christian Frezza;Maria Eugenia Soriano;Tatiana Varanita.
Cell (2013)

768 Citations

Succinate Dehydrogenase Supports Metabolic Repurposing of Mitochondria to Drive Inflammatory Macrophages

Evanna L. Mills;Beth Kelly;Angela Logan;Ana S.H. Costa.
Cell (2016)

766 Citations

Mitochondrial Rhomboid PARL Regulates Cytochrome c Release during Apoptosis via OPA1-Dependent Cristae Remodeling

Sara Cipolat;Tomasz Rudka;Dieter Hartmann;Veronica Costa.
Cell (2006)

752 Citations

Predicting selective drug targets in cancer through metabolic networks

Ori Folger;Livnat Jerby;Christian Frezza;Eyal Gottlieb.
Molecular Systems Biology (2011)

487 Citations

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