Christian Frezza

Overview

Best Publications

• Guidelines for the use and interpretation of assays for monitoring autophagy (3rd edition)

  Daniel J. Klionsky;Kotb Abdelmohsen;Akihisa Abe;Joynal Abedin

  8488
  Citations

• Succinate is an inflammatory signal that induces IL-1β through HIF-1α

  G. M. Tannahill;A. M. Curtis;J. Adamik;E. M. Palsson-McDermott

  4066
  Citations

• Ischaemic accumulation of succinate controls reperfusion injury through mitochondrial ROS.

  Edward T. Chouchani;Edward T. Chouchani;Victoria R. Pell;Edoardo Gaude;Dunja Aksentijević

  2510
  Citations

• Succinate Dehydrogenase Supports Metabolic Repurposing of Mitochondria to Drive Inflammatory Macrophages

  Evanna L. Mills;Beth Kelly;Angela Logan;Ana S.H. Costa

  2135
  Citations

• OPA1 Controls Apoptotic Cristae Remodeling Independently from Mitochondrial Fusion

  Christian Frezza;Sara Cipolat;Olga Martins de Brito;Massimo Micaroni

  1892
  Citations

• Itaconate is an anti-inflammatory metabolite that activates Nrf2 via alkylation of KEAP1.

  Evanna L Mills;Dylan G Ryan;Hiran A Prag;Dina Dikovskaya

  1783
  Citations

• Organelle isolation: functional mitochondria from mouse liver, muscle and cultured fibroblasts.

  Christian Frezza;Sara Cipolat;Luca Scorrano

  1277
  Citations

• Mitochondrial Cristae Shape Determines Respiratory Chain Supercomplexes Assembly and Respiratory Efficiency

  Sara Cogliati;Christian Frezza;Maria Eugenia Soriano;Tatiana Varanita

  1190
  Citations

• Guidelines for the use and interpretation of assays for monitoring autophagy (3rd edition)

  Daniel J. Klionsky;Kotb Abdelmohsen;Akihisa Abe;Joynal Abedin

  895
  Citations

• Mitochondrial Rhomboid PARL Regulates Cytochrome c Release during Apoptosis via OPA1-Dependent Cristae Remodeling

  Sara Cipolat;Tomasz Rudka;Dieter Hartmann;Veronica Costa

  868
  Citations

• A roadmap for interpreting 13 C metabolite labeling patterns from cells

  Joerg M. Buescher;Maciek R. Antoniewicz;Laszlo G. Boros;Shawn C Burgess

  695
  Citations

• Serine Is an Essential Metabolite for Effector T Cell Expansion

  Eric H. Ma;Glenn Bantug;Takla Griss;Stephanie Condotta

  658
  Citations

• Serine is a natural ligand and allosteric activator of pyruvate kinase M2

  Barbara Chaneton;Petra Hillmann;Liang Zheng;Agnès C. L. Martin

  653
  Citations

• A Unifying Mechanism for Mitochondrial Superoxide Production during Ischemia-Reperfusion Injury.

  Edward T. Chouchani;Victoria R. Pell;Andrew M. James;Lorraine M. Work

  643
  Citations

• Fumarate is an epigenetic modifier that elicits epithelial-to-mesenchymal transition

  Marco Sciacovelli;Emanuel Gonçalves;Timothy Isaac Johnson;Vincent Roberto Zecchini

  593
  Citations

• Predicting selective drug targets in cancer through metabolic networks

  Ori Folger;Livnat Jerby;Christian Frezza;Eyal Gottlieb

  575
  Citations

• Haem oxygenase is synthetically lethal with the tumour suppressor fumarate hydratase

  Christian Frezza;Liang Zheng;Ori Folger;Kartik N. Rajagopalan

  543
  Citations

• Parkinson's disease mutations in PINK1 result in decreased Complex I activity and deficient synaptic function

  Vanessa Morais;Patrik Verstreken;Anne Roethig;Joel Smet

  448
  Citations

• Mitochondria in cancer: not just innocent bystanders.

  Christian Frezza;Eyal Gottlieb

  340
  Citations

• Fumarate is an epigenetic modifier that elicits epithelial-to-mesenchymal transition (vol 537, pg 544, 2016)

  M Sciacovelli;E Goncalves;TI Johnson;VR Zecchini

  6
  Citations