World's Best Scientists 2026 revealed!

D-Index & Metrics

Biology and Biochemistry

D-Index
64
Citations
19524
World Ranking
9492
National Ranking
725

Overview

Stefano Pluchino is affiliated with the University of Cambridge in the United Kingdom and has an extensive publication record in neuroscience and related biomedical fields. Their research spans the intersection of molecular biology, neurology, immunology, and developmental neuroscience, focusing primarily on mechanisms underlying neuroinflammation, neurodegeneration, and neurogenesis.

The main fields of study for Stefano Pluchino include:

  • Neuroscience
  • Medicine
  • Biochemistry, Genetics and Molecular Biology

Their subfields of study reveal a concentration on specific biological and medical processes, notably:

  • Molecular Biology
  • Neurology
  • Immunology
  • Developmental Neuroscience
  • Pathology and Forensic Medicine

The topics featured in their research reflect key biological phenomena and clinical conditions such as:

  • Neuroinflammation and Neurodegeneration Mechanisms
  • Neurogenesis and neuroplasticity mechanisms
  • Extracellular vesicles in disease
  • Immune cells in cancer
  • Multiple Sclerosis Research Studies
  • Pluripotent Stem Cells Research
  • RNA Interference and Gene Delivery

Stefano Pluchino's recent notable papers paint a detailed picture of their research interests and collaborations:

  • Neural stem cells traffic functional mitochondria via extracellular vesicles (2021), published in PLoS Biology
  • Parkinson's disease, aging and adult neurogenesis: Wnt/β-catenin signalling as the key to unlock the mystery of endogenous brain repair (2020), published in Aging Cell
  • Mitochondrial complex I activity in microglia sustains neuroinflammation (2024), published in Nature
  • Refining rodent models of spinal cord injury (2020), published in Experimental Neurology
  • The role of neural stem cells in regulating glial scar formation and repair (2021), published in Cell and Tissue Research

Their frequent co-authors include:

  • Luca Peruzzotti-Jametti (47 joint publications)
  • Cory M. Willis (20 joint publications)
  • Alexandra M. Nicaise (19 joint publications)
  • Regan Hamel (15 joint publications)
  • Grzegorz Krzak (14 joint publications)

Publication venues regularly featuring Stefano Pluchino's work include:

  • bioRxiv (Cold Spring Harbor Laboratory) with 11 publications
  • SSRN Electronic Journal with 4 publications
  • Cell Stem Cell with 3 publications
  • Nature Metabolism with 3 publications
  • Experimental Neurology with 2 publications

Best Publications

  • Applying extracellular vesicles based therapeutics in clinical trials - an ISEV position paper

    Thomas Lener;Mario Gimona;Ludwig Aigner;Verena Börger

  • Vesiclepedia: a compendium for extracellular vesicles with continuous community annotation

    Hina Kalra;Richard J. Simpson;Hong Ji;Elena Aikawa

  • Injection of adult neurospheres induces recovery in a chronic model of multiple sclerosis

    Stefano Pluchino;Angelo Quattrini;Elena Brambilla;Angela Gritti

  • Microglia activated by IL-4 or IFN-γ differentially induce neurogenesis and oligodendrogenesis from adult stem/progenitor cells

    Oleg Butovsky;Yaniv Ziv;Adi Schwartz;Gennady Landa

  • The therapeutic potential of neural stem cells.

    Gianvito Martino;Stefano Pluchino

  • Infiltrating blood-derived macrophages are vital cells playing an anti-inflammatory role in recovery from spinal cord injury in mice.

    Ravid Shechter;Anat London;Chen Varol;Catarina Raposo

  • Neurosphere-derived multipotent precursors promote neuroprotection by an immunomodulatory mechanism.

    Stefano Pluchino;Lucia Zanotti;Barbara Rossi;Elena Brambilla

  • Delayed post-ischaemic neuroprotection following systemic neural stem cell transplantation involves multiple mechanisms

    Marco Bacigaluppi;Stefano Pluchino;Luca Peruzzotti Jametti;Ertugrul Kilic

  • The stem cell secretome and its role in brain repair.

    Denise Drago;Chiara Cossetti;Chiara Cossetti;Nunzio Iraci;Nunzio Iraci;Edoardo Gaude

  • Synergy between immune cells and adult neural stem/progenitor cells promotes functional recovery from spinal cord injury

    Yaniv Ziv;Hila Avidan;Stefano Pluchino;Gianvito Martino

  • A novel community driven software for functional enrichment analysis of extracellular vesicles data

    Mohashin Pathan;Shivakumar Keerthikumar;David Chisanga;Riccardo Alessandro

  • Extracellular Vesicles from Neural Stem Cells Transfer IFN-γ via Ifngr1 to Activate Stat1 Signaling in Target Cells

    Chiara Cossetti;Nunzio Iraci;Nunzio Iraci;Tim R. Mercer;Tommaso Leonardi

  • Focus on Extracellular Vesicles: Physiological Role and Signalling Properties of Extracellular Membrane Vesicles.

    Nunzio Iraci;Tommaso Leonardi;Tommaso Leonardi;Florian Gessler;Beatriz Vega

  • Brain regeneration in physiology and pathology: the immune signature driving therapeutic plasticity of neural stem cells.

    Gianvito Martino;Stefano Pluchino;Luca Bonfanti;Michal Schwartz

  • Persistent inflammation alters the function of the endogenous brain stem cell compartment.

    Stefano Pluchino;Luca Muzio;Jaime Imitola;Michela Deleidi

  • Transplanted neural stem/precursor cells instruct phagocytes and reduce secondary tissue damage in the injured spinal cord

    Melania Cusimano;Daniela Biziato;Elena Brambilla;Matteo Donegà

  • A Wnt1 regulated Frizzled-1/β-Catenin signaling pathway as a candidate regulatory circuit controlling mesencephalic dopaminergic neuron-astrocyte crosstalk: Therapeutical relevance for neuron survival and neuroprotection

    Francesca L'Episcopo;Maria F Serapide;Cataldo Tirolo;Nunzio Testa

  • Human neural stem cells ameliorate autoimmune encephalomyelitis in non-human primates

    Stefano Pluchino;Angela Gritti;Erwin Blezer;Stefano Amadio

  • Macrophage-Derived Extracellular Succinate Licenses Neural Stem Cells to Suppress Chronic Neuroinflammation

    Luca Peruzzotti-Jametti;Joshua D. Bernstock;Nunzio Vicario;Ana S.H. Costa

  • Applying extracellular vesicles based therapeutics in clinical trials

    Thomas Lener;Mario Gimona;Ludwig Aigner;Verena Börger

Frequent Co-Authors

Gianvito Martino
Gianvito Martino Vita-Salute San Raffaele University
Giancarlo Comi
Giancarlo Comi Vita-Salute San Raffaele University
Dirk M. Hermann
Dirk M. Hermann University of Duisburg-Essen
Roberto Furlan
Roberto Furlan San Raffaele Hospital
Christian Frezza
Christian Frezza University of Cambridge
John M. Hallenbeck
John M. Hallenbeck National Institutes of Health
Angela Bachi
Angela Bachi FIRC Institute of Molecular Oncology
José Manuel García-Verdugo
José Manuel García-Verdugo University of Valencia
Michal Schwartz
Michal Schwartz Weizmann Institute of Science
Anton J. Enright
Anton J. Enright University of Cambridge

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