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Biology and Biochemistry
Italy
2023

D-Index & Metrics

Biology and Biochemistry

D-Index
72
Citations
20394
World Ranking
6245
National Ranking
145

Research.com Recognitions

  • 2023 - Research.com Biology and Biochemistry in Italy Leader Award

Overview

Angela Bachi is affiliated with the FIRC Institute of Molecular Oncology in Italy. Their research spans multiple fields within the life sciences, chiefly focusing on Biochemistry, Genetics and Molecular Biology as well as Medicine. Their work frequently addresses key subfields such as Molecular Biology, Cell Biology, Spectroscopy, Oncology, and Physiology.

Their scientific publications focus on several recurring topics, including:

  • DNA Repair Mechanisms
  • RNA modifications and cancer
  • Endoplasmic Reticulum Stress and Disease
  • Cellular transport and secretion
  • Ubiquitin and proteasome pathways
  • Advanced Proteomics Techniques and Applications
  • Nuclear Structure and Function

Some of Angela Bachi's recent published papers include:

  • ATR is essential for preservation of cell mechanics and nuclear integrity during interstitial migration, 2020, Nature Communications
  • Vitamin C Restricts the Emergence of Acquired Resistance to EGFR-Targeted Therapies in Colorectal Cancer, 2020, Cancers
  • ATR expands embryonic stem cell fate potential in response to replication stress, 2020, eLife
  • Selenoprotein N is an endoplasmic reticulum calcium sensor that links luminal calcium levels to a redox activity, 2020, Proceedings of the National Academy of Sciences
  • FADS1/2 control lipid metabolism and ferroptosis susceptibility in triple-negative breast cancer, 2024, EMBO Molecular Medicine

Angela Bachi collaborates regularly with a group of frequent coauthors, including Vittoria Matafora, Angela Cattaneo, Umberto Restuccia, Vincenzo Costanzo, and Laura Tronci.

Their research output is often published in specific scientific venues, with multiple papers appearing in:

  • bioRxiv (Cold Spring Harbor Laboratory)
  • Nature Communications
  • Cell Reports
  • EMBO Molecular Medicine
  • Cell Reports Medicine

Best Publications

  • Monocytic cells hyperacetylate chromatin protein HMGB1 to redirect it towards secretion

    Tiziana Bonaldi;Fabio Talamo;Paola Scaffidi;Denise Ferrera

  • Mutually exclusive redox forms of HMGB1 promote cell recruitment or proinflammatory cytokine release

    Emilie Venereau;Maura Casalgrandi;Milena Schiraldi;Daniel J. Antoine

  • HMGB1 promotes recruitment of inflammatory cells to damaged tissues by forming a complex with CXCL12 and signaling via CXCR4

    Milena Schiraldi;Angela Raucci;Laura Martínez Muñoz;Elsa Livoti

  • TAP, the Human Homolog of Mex67p, Mediates CTE-Dependent RNA Export from the Nucleus

    Patric Grüter;Carlos Tabernero;Cayetano von Kobbe;Christel Schmitt

  • Identification by redox proteomics of glutathionylated proteins in oxidatively stressed human T lymphocytes.

    Maddalena Fratelli;Hans Demol;Magda Puype;Simona Casagrande

  • PHAX, a mediator of U snRNA nuclear export whose activity is regulated by phosphorylation.

    Mutsuhito Ohno;Alexandra Segref;Angela Bachi;Matthias Wilm

  • REF, an evolutionary conserved family of hnRNP-like proteins, interacts with TAP/Mex67p and participates in mRNA nuclear export.

    Françoise Stutz;Angela Bachi;Tobias Doerks;Isabelle C. Braun

  • A doughnut-shaped heteromer of human Sm-like proteins binds to the 3'-end of U6 snRNA, thereby facilitating U4/U6 duplex formation in vitro.

    Tilmann Achsel;Hero Brahms;Berthold Kastner;Angela Bachi

  • The C-terminal domain of TAP interacts with the nuclear pore complex and promotes export of specific CTE-bearing RNA substrates.

    A. Bachi;I. C. Braun;J. P. Rodrigues;N. Panté

  • A Common Core RNP Structure Shared between the Small Nucleoar Box C/D RNPs and the Spliceosomal U4 snRNP

    Nicholas J Watkins;Véronique Ségault;Bruno Charpentier;Bruno Charpentier;Stephanie Nottrott

  • The stem cell secretome and its role in brain repair.

    Denise Drago;Chiara Cossetti;Chiara Cossetti;Nunzio Iraci;Nunzio Iraci;Edoardo Gaude

  • Dbp5, a DEAD-box protein required for mRNA export, is recruited to the cytoplasmic fibrils of nuclear pore complex via a conserved interaction with CAN/Nup159p.

    Christel Schmitt;Cayetano von Kobbe;Angela Bachi;Nelly Panté

  • ERp44, a novel endoplasmic reticulum folding assistant of the thioredoxin family

    Tiziana Anelli;Massimo Alessio;Alexandre Mezghrani;Thomas Simmen

  • Extracellular Vesicles from Neural Stem Cells Transfer IFN-γ via Ifngr1 to Activate Stat1 Signaling in Target Cells

    Chiara Cossetti;Nunzio Iraci;Nunzio Iraci;Tim R. Mercer;Tommaso Leonardi

  • Thiol-mediated protein retention in the endoplasmic reticulum: the role of ERp44

    Tiziana Anelli;Massimo Alessio;Angela Bachi;Leda Bergamelli

  • CDKL5 ensures excitatory synapse stability by reinforcing NGL-1–PSD95 interaction in the postsynaptic compartment and is impaired in patient iPSC-derived neurons

    Sara Ricciardi;Federica Ungaro;Melanie Hambrock;Nils Rademacher

  • Redox proteomics: chemical principles, methodological approaches and biological/biomedical promises.

    Angela Bachi;Isabella Dalle-Donne;Andrea Scaloni

  • RanGTP-regulated interactions of CRM1 with nucleoporins and a shuttling DEAD-box helicase.

    Peter Askjaer;Angela Bachi;Matthias Wilm;F. Ralf Bischoff

  • Vesicular Stomatitis Virus Matrix Protein Inhibits Host Cell Gene Expression by Targeting the Nucleoporin Nup98

    Cayetano von Kobbe;Jan M.A. van Deursen;João P. Rodrigues;Delphine Sitterlin

  • RBM5/Luca-15/H37 Regulates Fas Alternative Splice Site Pairing after Exon Definition

    Sophie Bonnal;Concepción Martínez;Patrik Förch;Angela Bachi

Frequent Co-Authors

Matthias Wilm
Matthias Wilm University College Dublin
Pier Giorgio Righetti
Pier Giorgio Righetti Polytechnic University of Milan
Stefano Pluchino
Stefano Pluchino University of Cambridge
Egisto Boschetti
Egisto Boschetti Bio-Rad (United States)
Michele Perazzolli
Michele Perazzolli University of Trento
Fabio Benfenati
Fabio Benfenati Italian Institute of Technology
Claudio Doglioni
Claudio Doglioni Vita-Salute San Raffaele University
Paolo Ghia
Paolo Ghia Vita-Salute San Raffaele University
Renato Longhi
Renato Longhi National Academies of Sciences, Engineering, and Medicine
Alberto Diaspro
Alberto Diaspro Italian Institute of Technology

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