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Biology and Biochemistry
Italy
2023

D-Index & Metrics

Biology and Biochemistry

D-Index
78
Citations
20447
World Ranking
4573
National Ranking
100

Research.com Recognitions

  • 2023 - Research.com Biology and Biochemistry in Italy Leader Award
  • Member of the European Molecular Biology Organization (EMBO)
  • Member of the European Molecular Biology Organization (EMBO)
  • Member of the European Molecular Biology Organization (EMBO)

Overview

Roberto Sitia is affiliated with Vita-Salute San Raffaele University in Italy. Their research primarily spans the fields of Biochemistry, Genetics and Molecular Biology, with further contributions to Medicine. Key subfields of study include Cell Biology, Molecular Biology, Immunology, Infectious Diseases, and Genetics.

The scientist's work encompasses several main topics, among which are:

  • Endoplasmic Reticulum Stress and Disease
  • Cellular transport and secretion
  • Redox biology and oxidative stress
  • Mitochondrial Function and Pathology
  • Galectins and Cancer Biology
  • Reproductive System and Pregnancy
  • Endometriosis Research and Treatment

Frequent publication venues for Roberto Sitia include:

  • Free Radical Biology and Medicine
  • The EMBO Journal
  • The Journal of Cell Biology
  • Nature Communications
  • Journal of Biological Chemistry

Coauthor collaborations have been notable with researchers such as Tiziana Anelli, Ilaria Sorrentino, Iria Medraño-Fernández, Eelco van Anken, and Tiziana Tempio.

Recent papers authored or coauthored by Roberto Sitia include:

  • The endoplasmic reticulum kinase PERK interacts with the oxidoreductase ERO1 to metabolically adapt mitochondria (2022, Cell Reports)
  • Role of the early secretory pathway in SARS-CoV-2 infection (2020, The Journal of Cell Biology)
  • The importance of naturally attenuated SARS-CoV -2 in the fight against COVID-19 (2020, Environmental Microbiology)
  • Evolution, role in inflammation, and redox control of leaderless secretory proteins (2020, Journal of Biological Chemistry)
  • Zinc homeostasis governed by Golgi-resident ZnT family members regulates ERp44-mediated proteostasis at the ER-Golgi interface (2023, Nature Communications)

Roberto Sitia has been recognized as a member of the European Molecular Biology Organization (EMBO).

Best Publications

  • A novel secretory pathway for interleukin-1 beta, a protein lacking a signal sequence.

    A. Rubartelli;F. Cozzolino;M. Talio;R. Sitia

  • Quality control in the endoplasmic reticulum protein factory.

    Roberto Sitia;Ineke Braakman

  • Protein degradation in the endoplasmic reticulum

    Richard D. Klausner;Roberto Sitia

  • Protein quality control in the early secretory pathway

    Tiziana Anelli;Roberto Sitia

  • Secretion of thioredoxin by normal and neoplastic cells through a leaderless secretory pathway.

    A Rubartelli;A Bajetto;G Allavena;E Wollman

  • Antigen-presenting dendritic cells provide the reducing extracellular microenvironment required for T lymphocyte activation

    Giovanna Angelini;Stefania Gardella;Massimo Ardy;Maria Rosa Ciriolo

  • Plasma cells require autophagy for sustainable immunoglobulin production

    Niccolò Pengo;Maria Scolari;Laura Oliva;Enrico Milan

  • A novel pathway for secretory proteins

    Anne Muesch;Enno Hartmann;Klaus Rohde;Anna Rubartelli

  • Sequential Waves of Functionally Related Proteins Are Expressed When B Cells Prepare for Antibody Secretion

    Eelco van Anken;Edwin P Romijn;Claudia Maggioni;Alexandre Mezghrani

  • Immunoglobulin heavy-chain switching may be directed by prior induction of transcripts from constant-region genes

    Janet Stavnezer;Gail Radcliffe;Yi-Chaung Lin;Jennifer Nietupski

  • Monitoring dynamic changes in free Ca2+ concentration in the endoplasmic reticulum of intact cells.

    Mayte Montero;Marisa Brini;Robert Marsault;Javier Alvarez

  • Aggresomes and Russell bodies. Symptoms of cellular indigestion

    Ron R Kopito;Roberto Sitia

  • ERO1-L, a human protein that favors disulfide bond formation in the endoplasmic reticulum.

    Andrea Cabibbo;Massimiliano Pagani;Marco Fabbri;Mariano Rocchi

  • ERp44, a novel endoplasmic reticulum folding assistant of the thioredoxin family

    Tiziana Anelli;Massimo Alessio;Alexandre Mezghrani;Thomas Simmen

  • Endoplasmic Reticulum Oxidoreductin 1-Lβ (ERO1-Lβ), a Human Gene Induced in the Course of the Unfolded Protein Response

    Massimiliano Pagani;Marco Fabbri;Cristina Benedetti;Anna Fassio

  • Developmental regulation of IgM secretion: The role of the carboxy-terminal cysteine

    Roberto Sitia;Roberto Sitia;Michael Neuberger;Cristina Alberini;Paola Bet

  • Manipulation of oxidative protein folding and PDI redox state in mammalian cells.

    Alexandre Mezghrani;Anna Fassio;Adam Benham;Thomas Simmen

  • Thiol-mediated protein retention in the endoplasmic reticulum: the role of ERp44

    Tiziana Anelli;Massimo Alessio;Angela Bachi;Leda Bergamelli

  • The proteasome load versus capacity balance determines apoptotic sensitivity of multiple myeloma cells to proteasome inhibition

    Giada Bianchi;Laura Oliva;Paolo Cascio;Niccolò Pengo

  • Endoplasmic reticulum stress.

    Gábor Bánhegyi;Peter Baumeister;Angelo Benedetti;Dezheng Dong

Frequent Co-Authors

Anna Rubartelli
Anna Rubartelli National Cancer Research Institute, UK
Cristina M. Alberini
Cristina M. Alberini New York University
Kenji Inaba
Kenji Inaba University of Southern California
Ineke Braakman
Ineke Braakman Utrecht University
Ulrich Hämmerling
Ulrich Hämmerling Memorial Sloan Kettering Cancer Center
Cesar Milstein
Cesar Milstein MRC Laboratory of Molecular Biology
Angela Bachi
Angela Bachi FIRC Institute of Molecular Oncology
Gábor Bánhegyi
Gábor Bánhegyi Semmelweis University
G. Giacomo Consalez
G. Giacomo Consalez Vita-Salute San Raffaele University
Carlo E. Grossi
Carlo E. Grossi University of Genoa

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