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Marisa Brini

Marisa Brini

D-Index & Metrics

Biology and Biochemistry

D-Index
68
Citations
27780
World Ranking
7626
National Ranking
193

Overview

Marisa Brini is affiliated with the University of Padua in Italy and conducts research primarily in the fields of Biochemistry, Genetics and Molecular Biology, and Medicine. Their work spans a range of subfields including Molecular Biology, Cell Biology, Physiology, Neurology, and Infectious Diseases.

The scientist focuses on several main research topics, notably:

  • Mitochondrial Function and Pathology
  • Lipid Membrane Structure and Behavior
  • Ion Channel Regulation and Function
  • Endoplasmic Reticulum Stress and Disease
  • Neuroscience and Neuropharmacology Research
  • Cellular Transport and Secretion
  • Autophagy in Disease and Therapy

Marisa Brini has contributed to numerous publications with a concentration in journals such as Cell Death and Disease, International Journal of Molecular Sciences, Cell Calcium, bioRxiv (Cold Spring Harbor Laboratory), and Nature Communications. Frequent co-authors include Tito Calí, Lucia Barazzuol, Elena Poggio, Flavia Giamogante, and Dmitry Lim.

Selected recent papers demonstrate the scope and recurring themes in their research:

  • "PINK1/Parkin Mediated Mitophagy, Ca2+ Signalling, and ER-Mitochondria Contacts in Parkinson's Disease," 2020, International Journal of Molecular Sciences
  • "Ca2+ handling at the mitochondria-ER contact sites in neurodegeneration," 2021, Cell Calcium
  • "An expanded palette of improved SPLICS reporters detects multiple organelle contacts in vitro and in vivo," 2020, Nature Communications
  • "Quantification of organelle contact sites by split-GFP-based contact site sensors (SPLICS) in living cells," 2021, Nature Protocols
  • "Mitochondria Dysfunction and Neuroinflammation in Neurodegeneration: Who Comes First?," 2024, Antioxidants

The scope of their work involves detailed studies of cellular mechanisms, such as mitochondrial and endoplasmic reticulum interactions, calcium signaling, and autophagy relevant to neurodegeneration and other pathologies. These areas reflect an interdisciplinary approach connecting molecular function and disease processes.

Marisa Brini's research portfolio contributes to understanding complex cellular pathways associated with neurological diseases and mitochondrial health, maintaining an emphasis on molecular and cellular biology as well as physiology.

Best Publications

  • Guidelines for the use and interpretation of assays for monitoring autophagy (3rd edition)

    Daniel J. Klionsky;Kotb Abdelmohsen;Akihisa Abe;Joynal Abedin

  • Microdomains with high Ca2+ close to IP3-sensitive channels that are sensed by neighboring mitochondria

    Rosario Rizzuto;Marisa Brini;Marta Murgia;Tullio Pozzan

  • Rapid changes of mitochondrial Ca2+ revealed by specifically targeted recombinant aequorin.

    Rosario Rizzuto;Alec W. M. Simpson;Alec W. M. Simpson;Marisa Brini;Tullio Pozzan

  • Guidelines for the use and interpretation of assays for monitoring autophagy (3rd edition)

    Daniel J. Klionsky;Kotb Abdelmohsen;Akihisa Abe;Joynal Abedin

  • Generation, control, and processing of cellular calcium signals.

    Ernesto Carafoli;Luigia Santella;Donata Branca;Marisa Brini

  • Calcium Pumps in Health and Disease

    Marisa Brini;Ernesto Carafoli

  • Transient and Long-Lasting Openings of the Mitochondrial Permeability Transition Pore Can Be Monitored Directly in Intact Cells by Changes in Mitochondrial Calcein Fluorescence

    Valeria Petronilli;Giovanni Miotto;Marcella Canton;Marisa Brini

  • Neuronal calcium signaling: function and dysfunction

    Marisa Brini;Tito Calì;Denis Ottolini;Ernesto Carafoli

  • Chimeric green fluorescent protein as a tool for visualizing subcellular organelles in living cells

    Rosario Rizzuto;Marisa Brini;Paola Pizzo;Marta Murgia

  • Transfected Aequorin in the Measurement of Cytosolic Ca2+ Concentration ([Ca2+]c) A CRITICAL EVALUATION

    Marisa Brini;Robert Marsault;Carlo Bastianutto;Javier Alvarez

  • Mitochondrial Ca2+ homeostasis in intact cells.

    Rosario Rizzuto;Carlo Bastianutto;Marisa Brini;Marta Murgia

  • Monitoring dynamic changes in free Ca2+ concentration in the endoplasmic reticulum of intact cells.

    Mayte Montero;Marisa Brini;Robert Marsault;Javier Alvarez

  • Mitochondria, calcium and cell death: A deadly triad in neurodegeneration

    Fulvio Celsi;Paola Pizzo;Marisa Brini;Sara Leo;Sara Leo

  • The plasma membrane Ca²+ ATPase and the plasma membrane sodium calcium exchanger cooperate in the regulation of cell calcium.

    Marisa Brini;Ernesto Carafoli

  • α-Synuclein controls mitochondrial calcium homeostasis by enhancing endoplasmic reticulum-mitochondria interactions.

    Tito Calì;Denis Ottolini;Alessandro Negro;Marisa Brini

  • Double labelling of subcellular structures with organelle-targeted GFP mutants in vivo

    Rosario Rizzuto;Marisa Brini;Francesca De Giorgi;Raffaela Rossi

  • Subcellular imaging of intramitochondrial Ca2+ with recombinant targeted aequorin: significance for the regulation of pyruvate dehydrogenase activity.

    Guy A. Rutter;Paul Burnett;Rosario Rizzuto;Marisa Brini

  • Erratum to: Guidelines for the use and interpretation of assays for monitoring autophagy (3rd edition) (Autophagy, 12, 1, 1-222, 10.1080/15548627.2015.1100356

    Daniel J. Klionsky;Kotb Abdelmohsen;Akihisa Abe;Joynal Abedin

  • The Parkinson disease-related protein DJ-1 counteracts mitochondrial impairment induced by the tumour suppressor protein p53 by enhancing endoplasmic reticulum–mitochondria tethering

    Denis Ottolini;Tito Calì;Alessandro Negro;Marisa Brini

  • Nuclear Ca2+ concentration measured with specifically targeted recombinant aequorin.

    Marisa Brini;Marta Murgia;L Pasti;D Picard

Frequent Co-Authors

Rosario Rizzuto
Rosario Rizzuto University of Padua
Tullio Pozzan
Tullio Pozzan University of Padua
Ernesto Carafoli
Ernesto Carafoli University of Padua
Paolo Pinton
Paolo Pinton University of Ferrara
Ildikò Szabò
Ildikò Szabò University of Padua
Evelina Gatti
Evelina Gatti Aix-Marseille University
Paola Pizzo
Paola Pizzo University of Padua
Shazib Pervaiz
Shazib Pervaiz National University of Singapore
Beth Levine
Beth Levine The University of Texas Southwestern Medical Center
Eric A. Schon
Eric A. Schon Columbia University Medical Center

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