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Biology and Biochemistry

D-Index
58
Citations
11969
World Ranking
13184
National Ranking
272

Research.com Recognitions

  • 1999 - Member of Academia Europaea

Overview

Javier García-Sancho is affiliated with the Spanish National Research Council in Spain. Their research encompasses several areas within medicine and biochemistry, genetics, and molecular biology, with a particular focus on cellular and molecular studies.

The main fields of study in their work include:

  • Medicine
  • Biochemistry, Genetics and Molecular Biology

More specifically, their research covers subfields such as:

  • Cell Biology
  • Molecular Biology
  • Cellular and Molecular Neuroscience
  • Pharmacology
  • Pathology and Forensic Medicine

The key topics addressed in their publications are:

  • Cellular transport and secretion
  • Musculoskeletal pain and rehabilitation
  • Spine and Intervertebral Disc Pathology
  • Neurobiology and Insect Physiology Research
  • Mesenchymal stem cell research
  • Bioluminescence and chemiluminescence research
  • Ion channel regulation and function

They have several joint works with frequent co-authors including:

  • Jonathan Rojo-Ruiz
  • Marı́a Teresa Alonso
  • Alba Delrio-Lorenzo
  • Patricia Torres-vidal
  • Belén Calvo

García-Sancho's research has been published in multiple venues such as:

  • Annals of the Rheumatic Diseases
  • Transplantation
  • Journal of Cell Science
  • Journal of Translational Medicine
  • Biochimica et Biophysica Acta (BBA) - Molecular Cell Research

Their recent papers include:

  • Treatment of Degenerative Disc Disease With Allogeneic Mesenchymal Stem Cells: Long-term Follow-up Results, 2021, Transplantation
  • Direct monitoring of ER Ca2+ dynamics reveals that Ca2+ entry induces ER-Ca2+ release in astrocytes, 2020, Pflügers Archiv - European Journal of Physiology
  • Sarcoplasmic reticulum Ca2+ decreases with age and correlates with the decline in muscle function in Drosophila, 2020, Journal of Cell Science
  • Long-term efficacy of autologous bone marrow mesenchymal stromal cells for treatment of knee osteoarthritis, 2021, Journal of Translational Medicine
  • Allogenic bone marrow-derived mesenchymal stromal cell-based therapy for patients with chronic low back pain: a prospective, multicentre, randomised placebo controlled trial (RESPINE study), 2024, Annals of the Rheumatic Diseases

In 1999, Javier García-Sancho was recognized as a Member of the Academia Europaea.

Best Publications

  • Treatment of Knee Osteoarthritis With Allogeneic Bone Marrow Mesenchymal Stem Cells: A Randomized Controlled Trial.

    Aurelio Vega;Miguel Angel Martín-Ferrero;Francisco Del Canto;Mercedes Alberca

  • Experimental and Clinical Regenerative Capability of Human Bone Marrow Cells After Myocardial Infarction

    Francisco Fernández-Avilés;José Alberto San Román;Javier García-Frade;María Eugenia Fernández

  • Intervertebral disc repair by autologous mesenchymal bone marrow cells: a pilot study.

    Lluis Orozco;Robert Soler;Carles Morera;Mercedes Alberca

  • Chromaffin-cell stimulation triggers fast millimolar mitochondrial Ca2+ transients that modulate secretion.

    Mayte Montero;Maria Teresa Alonso;Estela Carnicero;Inmaculada Cuchillo-Ibáñez

  • Treatment of knee osteoarthritis with autologous mesenchymal stem cells: a pilot study

    Lluis Orozco;Anna Munar;Robert Soler;Mercedes Alberca

  • WIDESPREAD SYNCHRONOUS CA2+I OSCILLATIONS DUE TO BURSTING ELECTRICAL ACTIVITY IN SINGLE PANCREATIC ISLETS

    Rosa M. Santos;Luis M. Rosario;Angel Nadal;Javier Garcia-Sancho

  • Calcium Signaling and Exocytosis in Adrenal Chromaffin Cells

    Antonio G. García;Antonio M. García-De-Diego;Luis Gandía;Ricardo Borges

  • High affinity inhibition of Ca(2+)-dependent K+ channels by cytochrome P-450 inhibitors

    J Alvarez;M Montero;J Garcia-Sancho

  • Intervertebral Disc Repair by Allogeneic Mesenchymal Bone Marrow Cells: A Randomized Controlled Trial.

    David C. Noriega;Francisco Ardura;Rubén Hernández-Ramajo;Miguel Ángel Martín-Ferrero

  • Cytochrome P-450 may link intracellular Ca2+ stores with plasma membrane Ca2+ influx

    J Alvarez;M Montero;J García-Sancho

  • Ca2+-induced Ca2+ Release in Chromaffin Cells Seen from inside the ER with Targeted Aequorin

    Maria Teresa Alonso;Maria José Barrero;Pedro Michelena;Estela Carnicero

  • Agonist-induced Ca2+ influx in human neutrophils is secondary to the emptying of intracellular calcium stores.

    M Montero;J Alvarez;J Garcia-Sancho

  • Treatment of knee osteoarthritis with autologous mesenchymal stem cells: two-year follow-up results.

    Lluis Orozco;Anna Munar;Robert Soler;Mercedes Alberca

  • Calcium Influx through Receptor-operated Channel Induces Mitochondria-triggered Paraptotic Cell Death ,

    Enrique Jambrina;Roberto Alonso;Marta Alcalde;Marı́a del Carmen Rodrı́guez

  • Redistribution of Ca2+ among cytosol and organella during stimulation of bovine chromaffin cells

    Carlos Villalobos;Lucía Nuñez;Mayte Montero;Antonio G. García

  • Cytochrome P450 may regulate plasma membrane Ca2+ permeability according to the filling state of the intracellular Ca2+ stores.

    Javier Alvarez;Mayte Montero;Javier Garcia-Sancho

  • Calcium microdomains in mitochondria and nucleus

    María Teresa Alonso;Carlos Villalobos;Pablo Chamero;Javier Alvarez

  • Irreversible ATP depletion caused by low concentrations of formaldehyde and of calcium-chelator esters in intact human red cells

    Teresa Tiffert;Javier Garcia-Sancho;Virgilio L. Lew

  • The Eutherian Armcx genes regulate mitochondrial trafficking in neurons and interact with Miro and Trak2.

    Guillermo López-Doménech;Román Serrat;Serena Mirra;Salvatore D'Aniello;Salvatore D'Aniello

  • Cell proliferation depends on mitochondrial Ca2+ uptake: inhibition by salicylate.

    Lucía Núñez;Ruth A. Valero;Laura Senovilla;Sara Sanz-Blasco

Frequent Co-Authors

Laura Senovilla
Laura Senovilla University of Valladolid
Virgilio L. Lew
Virgilio L. Lew University of Cambridge
Faustino Mollinedo
Faustino Mollinedo University of Salamanca
Angel Nadal
Angel Nadal Miguel Hernandez University
Bernhard Kuster
Bernhard Kuster Technical University of Munich
Angel Raya
Angel Raya Institució Catalana de Recerca i Estudis Avançats
Bernat Soria
Bernat Soria Spanish National Research Council
Salvador Martinez
Salvador Martinez Miguel Hernandez University
Lina Badimon
Lina Badimon Hospital de la Santa Creu i Sant Pau
Jordi Garcia-Fernàndez
Jordi Garcia-Fernàndez University of Barcelona

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