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Biology and Biochemistry

D-Index
60
Citations
8915
World Ranking
12221
National Ranking
939

Overview

Stewart O. Sage is affiliated with the University of Cambridge in the United Kingdom. Their research focuses on several areas within neuroscience, biochemistry, genetics and molecular biology, and medicine.

Their main fields of study include:

  • Neuroscience
  • Biochemistry, Genetics and Molecular Biology
  • Medicine

Within these, the prominent subfields are:

  • Physiology
  • Sensory Systems

The primary research topics addressed in their work include:

  • Ion Channels and Receptors
  • Calcium signaling and nucleotide metabolism
  • Erythrocyte Function and Pathophysiology

Stewart O. Sage has published research in several scientific venues, with a concentration in the journal Cell Calcium.

One of their recent publications is:

  • Calcium sequestration by human platelet acidic organelles is regulated by the actin cytoskeleton and autocrine 5-hydroxytryptamine, 2021, Cell Calcium

This publication has been cited in the academic community, contributing to ongoing studies in calcium-related cellular mechanisms.

The scientist frequently collaborates with other researchers in their field, including Alan G.S. Harper.

Best Publications

  • The kinetics of changes in intracellular calcium concentration in fura-2-loaded human platelets.

    SO Sage;TJ Rink

  • Receptor-mediated calcium entry in fura-2-loaded human platelets stimulated with ADP and thrombin. Dual-wavelengths studies with Mn2+.

    S O Sage;J E Merritt;T J Hallam;T J Rink

  • Activation of receptor-operated cation channels via P2X1 not P2T purinoceptors in human platelets.

    Amanda B. MacKenzie;Martyn P. Mahaut-Smith;Stewart O. Sage

  • A Role for the Actin Cytoskeleton in the Initiation and Maintenance of Store-mediated Calcium Entry in Human Platelets EVIDENCE FOR CONFORMATIONAL COUPLING

    Juan A. Rosado;Susanne Jenner;Stewart O. Sage

  • ADP- and thapsigargin-evoked Ca2+ entry and protein-tyrosine phosphorylation are inhibited by the tyrosine kinase inhibitors genistein and methyl-2,5-dihydroxycinnamate in fura-2-loaded human platelets.

    P Sargeant;R W Farndale;S O Sage

  • Coupling between inositol 1,4,5-trisphosphate receptors and human transient receptor potential channel 1 when intracellular Ca2+ stores are depleted.

    Juan A. Rosado;Stewart O. Sage

  • Shedding of procoagulant microparticles from unstimulated platelets by integrin-mediated destabilization of actin cytoskeleton

    Sandra Cauwenberghs;Marion A.H. Feijge;Alan G.S. Harper;Stewart O. Sage

  • ADP evokes biphasic Ca2+ influx in fura-2-loaded human platelets. Evidence for Ca2+ entry regulated by the intracellular Ca2+ store.

    S O Sage;R Reast;T J Rink

  • The actin cytoskeleton in store‐mediated calcium entry

    Juan A. Rosado;Stewart O. Sage

  • TRPC channels and store-operated Ca2+ entry

    Ginés M. Salido;Stewart O. Sage;Juan A. Rosado

  • Endogenously Expressed Trp1 Is Involved in Store-mediated Ca2+ Entry by Conformational Coupling in Human Platelets

    Juan A. Rosado;Sharon L. Brownlow;Stewart O. Sage

  • Calcium-activated potassium channels in the endothelium of intact rat aorta.

    S M Marchenko;S O Sage

  • Activation of store-mediated calcium entry by secretion-like coupling between the inositol 1,4,5-trisphosphate receptor type II and human transient receptor potential (hTrp1) channels in human platelets.

    Juan A. Rosado;Stewart O. Sage

  • The tyrosine kinase inhibitors methyl 2,5-dihydroxycinnamate and genistein reduce thrombin-evoked tyrosine phosphorylation and Ca2+ entry in human platelets

    Paul Sargeant;Richard W. Farndale;Stewart O. Sage

  • Transient receptor potential protein subunit assembly and membrane distribution in human platelets.

    Sharon L. Brownlow;Stewart O. Sage

  • Hydrogen Peroxide Generation Induces pp60src Activation in Human Platelets EVIDENCE FOR THE INVOLVEMENT OF THIS PATHWAY IN STORE-MEDIATED CALCIUM ENTRY

    Juan A. Rosado;Pedro C. Redondo;Ginés M. Salido;Emilio Gómez-Arteta

  • Non-redundant Roles of Phosphoinositide 3-Kinase Isoforms α and β in Glycoprotein VI-induced Platelet Signaling and Thrombus Formation

    Karen Gilio;Imke C A Munnix;Pierre Mangin;Judith M E M Cosemans

  • Calcium signalling in platelets and other cells.

    J. W. M. Heemskerk;S. O. Sage

  • Calcium influx evoked by Ca2+ store depletion in human platelets is more susceptible to cytochrome P-450 inhibitors than receptor-mediated calcium entry

    P. Sargeant;W.D. Clarkson;S.O. Sage;J.W.M. Heemskerk

  • Bradykinin-evoked changes in cytosolic calcium and membrane currents in cultured bovine pulmonary artery endothelial cells.

    M B Cannell;S O Sage

Frequent Co-Authors

Juan A. Rosado
Juan A. Rosado University of Extremadura
Richard W. Farndale
Richard W. Farndale University of Cambridge
Johan W. M. Heemskerk
Johan W. M. Heemskerk Maastricht University
Ginés M. Salido
Ginés M. Salido University of Extremadura
José A. Pariente
José A. Pariente University of Extremadura
Robert S. Reneman
Robert S. Reneman Maastricht University
Song Li
Song Li University of California, Los Angeles
Shu Chien
Shu Chien University of California, San Diego
Shaun P. Jackson
Shaun P. Jackson University of Sydney
Lucilla Poston
Lucilla Poston King's College London

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