Christian Gachet

Research.com Recognitions

• 2023 - Research.com Biology and Biochemistry in France Leader Award

Overview

Best Publications

• International Union of Pharmacology LVIII: Update on the P2Y G Protein-Coupled Nucleotide Receptors: From Molecular Mechanisms and Pathophysiology to Therapy

  Maria Pia Abbracchio;Geoffrey Burnstock;Jean-Marie Boeynaems;Eric A Barnard

  1568
  Citations

• Consensus and Future Directions on the Definition of High On-Treatment Platelet Reactivity to Adenosine Diphosphate

  Laurent Bonello;Udaya S. Tantry;Rossella Marcucci;Ruediger Blindt

  1373
  Citations

• Platelet-Derived Serotonin Mediates Liver Regeneration

  Mickael Lesurtel;Rolf Graf;Boris Aleil;Diego J. Walther

  911
  Citations

• Defective platelet aggregation and increased resistance to thrombosis in purinergic P2Y1 receptor–null mice

  Catherine Léon;Béatrice Hechler;Monique Freund;Anita Eckly

  618
  Citations

• ADP receptors of platelets and their inhibition.

  Christian Gachet

  596
  Citations

• Characterization of the UDP-glucose receptor (re-named here the P2Y14 receptor) adds diversity to the P2Y receptor family.

  Maria Pia Abbracchio;Jean-Marie Boeynaems;Eric A Barnard;José L Boyer

  559
  Citations

• Flow cytometric analysis of intraplatelet VASP phosphorylation for the detection of clopidogrel resistance in patients with ischemic cardiovascular diseases.

  B. Aleil;C. Ravanat;J. P. Cazenave;G. Rochoux

  556
  Citations

• Long-Term Antithrombotic Protection by in Vivo Depletion of Platelet Glycoprotein VI in Mice

  Bernhard Nieswandt;Valerie Schulte;Wolfgang Bergmeier;Rabée Mokhtari-Nejad

  450
  Citations

• The P2Y1 receptor is an ADP receptor antagonized by ATP and expressed in platelets and megakaryoblastic cells

  Catherine Léon;Béatrice Hechler;Catherine Vial;Claude Leray

  425
  Citations

• P2 receptors, platelet function and pharmacological implications

  Christian Gachet

  382
  Citations

• Transformation of Astrocytes to a Neuroprotective Phenotype by Microglia via P2Y1 Receptor Downregulation

  Youichi Shinozaki;Keisuke Shibata;Keitaro Yoshida;Eiji Shigetomi

  381
  Citations

• The P2Y1 Receptor Is Necessary for Adenosine 5′-Diphosphate–Induced Platelet Aggregation

  Béatrice Hechler;Catherine Léon;Catherine Léon;Catherine Vial;Catherine Vial;Paul Vigne;Paul Vigne

  370
  Citations

• Regulation of platelet functions by P2 receptors.

  Christian Gachet

  369
  Citations

• Migrating Platelets Are Mechano-scavengers that Collect and Bundle Bacteria.

  Florian Gaertner;Zerkah Ahmad;Gerhild Rosenberger;Shuxia Fan

  344
  Citations

• Possible Involvement of P2Y2 Metabotropic Receptors in ATP-Induced Transient Receptor Potential Vanilloid Receptor 1-Mediated Thermal Hypersensitivity

  Tomoko Moriyama;Tohko Iida;Kimiko Kobayashi;Tomohiro Higashi

  335
  Citations

• A Key Role of Adenosine Diphosphate in the Irreversible Platelet Aggregation Induced by the PAR1-Activating Peptide Through the Late Activation of Phosphoinositide 3-Kinase

  Catherine Trumel;Bernard Payrastre;Monique Plantavid;Béatrice Hechler

  307
  Citations

• Mechanisms underlying FeCl3-induced arterial thrombosis.

  A. Eckly;B. Hechler;M. Freund;M. Zerr

  289
  Citations

• A role of the fast ATP-gated P2X1 cation channel in thrombosis of small arteries in vivo.

  Béatrice Hechler;Nadège Lenain;Patrizia Marchese;Catherine Vial

  275
  Citations

• Preparation of washed platelet suspensions from human and rodent blood.

  Jean-Pierre Cazenave;Philippe Ohlmann;Dominique Cassel;Anita Eckly

  268
  Citations

• ADP Receptors and Clinical Bleeding Disorders

  Marco Cattaneo;Christian Gachet

  264
  Citations