His primary scientific interests are in Platelet, Cell biology, Molecular biology, Thrombin and Von Willebrand factor. His Platelet study is concerned with Internal medicine in general. The study incorporates disciplines such as Integrin, Biogenesis and Immunology in addition to Cell biology.
His work deals with themes such as Complementary DNA, Peptide sequence, Chinese hamster ovary cell and Transmembrane domain, which intersect with Molecular biology. In general Thrombin study, his work on Thrombomodulin, Thrombin receptor and Protease-activated receptor often relates to the realm of Adenosine diphosphate, thereby connecting several areas of interest. His Von Willebrand factor study combines topics from a wide range of disciplines, such as Calcium in biology, Cell surface receptor, Protein kinase C and Tyrosine phosphorylation.
His main research concerns Platelet, Cell biology, Molecular biology, Platelet activation and Thrombin. Platelet and Endocrinology are frequently intertwined in his study. His study explores the link between Cell biology and topics such as Integrin that cross with problems in Tetraspanin and Cell adhesion.
His research investigates the connection between Molecular biology and topics such as Immunoprecipitation that intersect with issues in Epitope. His Platelet activation research includes elements of Receptor, Prothrombinase, Pathology and Fibrin. His studies in Thrombin integrate themes in fields like Thrombosis and Biochemistry.
François Lanza mainly investigates Platelet, Cell biology, Pathology, Tubulin and Haematopoiesis. His Platelet activation study in the realm of Platelet connects with subjects such as Organ transplantation. The concepts of his Cell biology study are interwoven with issues in Cell and Biogenesis.
His Pathology research incorporates themes from Thrombosis, Abnormal Platelet and Thyroid dysgenesis. His Tubulin research includes themes of Acetyltransferase, Endocrinology and Abnormal platelet morphology. As a part of the same scientific family, François Lanza mostly works in the field of Thrombin, focusing on Glycoprotein and, on occasion, Von Willebrand factor.
Platelet, Cell biology, Megakaryocyte, Biogenesis and Thrombopoiesis are his primary areas of study. The Platelet study combines topics in areas such as Platelet production and Intensive care medicine. François Lanza interconnects Tubulin, Microtubule, Isotype and Myosin in the investigation of issues within Megakaryocyte.
His work carried out in the field of Microtubule brings together such families of science as Cytoplasm, Haematopoiesis, Megakaryocytopoiesis, Cytoskeleton and In vivo. His Biogenesis research is multidisciplinary, incorporating elements of Mutation, Triphosphatase, Platelet activation and Oculocutaneous albinism. The various areas that François Lanza examines in his Thrombopoiesis study include Cell, Podosome, Sinusoid, Bone marrow and Giant cell.
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A revised model of platelet aggregation
Suhasini Kulkarni;Sacha M Dopheide;Cindy L Yap;Catherine Ravanat.
Journal of Clinical Investigation (2000)
Selective tetraspan-integrin complexes (CD81/alpha4beta1, CD151/alpha3beta1, CD151/alpha6beta1) under conditions disrupting tetraspan interactions.
Serru;Le Naour F;Billard M;Azorsa Do.
Biochemical Journal (1999)
Mechanisms underlying FeCl3-induced arterial thrombosis.
A. Eckly;B. Hechler;M. Freund;M. Zerr.
Journal of Thrombosis and Haemostasis (2011)
Profiling of the Tetraspanin Web of Human Colon Cancer Cells
François Le Naour;Magali André;Céline Greco;Martine Billard.
Molecular & Cellular Proteomics (2006)
Megakaryocyte-restricted MYH9 inactivation dramatically affects hemostasis while preserving platelet aggregation and secretion
Catherine Léon;Anita Eckly;Béatrice Hechler;Boris Aleil.
Blood (2007)
Expression of Platelet Glycoprotein (GP) V in Heterologous Cells and Evidence for Its Association with GP Ibα in Forming a GP Ib-IX-V Complex on the Cell Surface
Chester Q. Li;Jing Fei Dong;François Lanza;David A. Sanan.
Journal of Biological Chemistry (1995)
MRS2500 [2-Iodo-N6-methyl-(N)-methanocarba-2′-deoxyadenosine-3′,5′-bisphosphate], a Potent, Selective, and Stable Antagonist of the Platelet P2Y1 Receptor with Strong Antithrombotic Activity in Mice
Béatrice Hechler;Christelle Nonne;Eun Joo Roh;Marco Cattaneo.
Journal of Pharmacology and Experimental Therapeutics (2006)
Cloning and characterization of the gene encoding the human platelet glycoprotein V. A member of the leucine-rich glycoprotein family cleaved during thrombin-induced platelet activation.
F Lanza;M Morales;J P Cazenave.
Journal of Biological Chemistry (1993)
A new variant of Glanzmann's thrombasthenia (Strasbourg I). Platelets with functionally defective glycoprotein IIb-IIIa complexes and a glycoprotein IIIa 214Arg----214Trp mutation.
F Lanza;A Stierlé;D Fournier;M Morales.
Journal of Clinical Investigation (1992)
The von Willebrand Factor-Glycoprotein Ib/V/IX Interaction Induces Actin Polymerization and Cytoskeletal Reorganization in Rolling Platelets and Glycoprotein Ib/V/IX-transfected Cells
Yuping Yuan;Suhasini Kulkarni;Philippe Ulsemer;Susan L Cranmer.
Journal of Biological Chemistry (1999)
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