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Biology and Biochemistry

D-Index
62
Citations
10750
World Ranking
11022
National Ranking
398

Overview

François Lanza is affiliated with the University of Strasbourg in France and has an extensive research record primarily in the fields of Medicine and Biochemistry, Genetics and Molecular Biology. Their work focuses particularly on hematology, molecular biology, pulmonary and respiratory medicine, cell biology, and genetics.

The scientist's publications concentrate on topics related to platelet disorders and treatments, blood properties and coagulation, blood groups and transfusion, glycosylation and glycoproteins research, cell adhesion molecules research, antiplatelet therapy and cardiovascular diseases, and heparin-induced thrombocytopenia and thrombosis.

Frequent coauthors in Lanza's research include:

  • Christian Gachet
  • Anita Eckly
  • Catherine Strassel
  • Catherine Léon
  • Léa Mallo

Common publication venues for their work are:

  • Journal of Visualized Experiments
  • Journal of Thrombosis and Haemostasis
  • Blood
  • Arteriosclerosis Thrombosis and Vascular Biology
  • Haematologica

Selected recent papers include:

  • Pharmacological Blockade of Glycoprotein VI Promotes Thrombus Disaggregation in the Absence of Thrombin, 2020, Arteriosclerosis Thrombosis and Vascular Biology
  • Megakaryocytes use in vivo podosome-like structures working collectively to penetrate the endothelial barrier of bone marrow sinusoids, 2020, Journal of Thrombosis and Haemostasis
  • Cytoskeletal-based mechanisms differently regulate in vivo and in vitro proplatelet formation, 2020, Haematologica
  • Blood platelet formation at a glance, 2020, Journal of Cell Science
  • Desialylation of O-glycans on glycoprotein Ibα drives receptor signaling and platelet clearance, 2020, Haematologica

Best Publications

  • A revised model of platelet aggregation

    Suhasini Kulkarni;Sacha M Dopheide;Cindy L Yap;Catherine Ravanat

  • Selective tetraspan-integrin complexes (CD81/alpha4beta1, CD151/alpha3beta1, CD151/alpha6beta1) under conditions disrupting tetraspan interactions.

    Serru;Le Naour F;Billard M;Azorsa Do

  • Mechanisms underlying FeCl3-induced arterial thrombosis.

    A. Eckly;B. Hechler;M. Freund;M. Zerr

  • Megakaryocyte-restricted MYH9 inactivation dramatically affects hemostasis while preserving platelet aggregation and secretion

    Catherine Léon;Anita Eckly;Béatrice Hechler;Boris Aleil

  • Profiling of the Tetraspanin Web of Human Colon Cancer Cells

    François Le Naour;Magali André;Céline Greco;Martine Billard

  • Expression of Platelet Glycoprotein (GP) V in Heterologous Cells and Evidence for Its Association with GP Ibα in Forming a GP Ib-IX-V Complex on the Cell Surface

    Chester Q. Li;Jing Fei Dong;François Lanza;David A. Sanan

  • MRS2500 [2-Iodo-N6-methyl-(N)-methanocarba-2′-deoxyadenosine-3′,5′-bisphosphate], a Potent, Selective, and Stable Antagonist of the Platelet P2Y1 Receptor with Strong Antithrombotic Activity in Mice

    Béatrice Hechler;Christelle Nonne;Eun Joo Roh;Marco Cattaneo

  • Selective tetraspan–integrin complexes (CD81/α4β1, CD151/α3β1, CD151/α6β1) under conditions disrupting tetraspan interactions

    Valérie Serru;LE Naour François;Martine Billard;David O. Azorsa

  • Cloning and characterization of the gene encoding the human platelet glycoprotein V. A member of the leucine-rich glycoprotein family cleaved during thrombin-induced platelet activation.

    F Lanza;M Morales;J P Cazenave

  • Thrombin overcomes the thrombosis defect associated with platelet GPVI/FcRγ deficiency

    Pierre Mangin;Pierre Mangin;Pierre Mangin;Cindy Li Shen Yap;Cindy Li Shen Yap;Cindy Li Shen Yap;C Nonne;C Nonne;C Nonne;Sharelle Anne Sturgeon;Sharelle Anne Sturgeon;Sharelle Anne Sturgeon

  • Bernard-Soulier syndrome (Hemorrhagiparous thrombocytic dystrophy)

    François Lanza

  • Platelet glycoprotein V binds to collagen and participates in platelet adhesion and aggregation.

    Sylvie Moog;Pierre Mangin;Nadège Lenain;Catherine Strassel

  • Epinephrine potentiates human platelet activation but is not an aggregating agent

    F. Lanza;A. Beretz;A. Stierle;D. Hanau

  • Spectrum of the mutations in bernard-soulier syndrome

    Anna Savoia;Shinji Kunishima;Daniela De Rocco;Barbara Zieger

  • The von Willebrand Factor-Glycoprotein Ib/V/IX Interaction Induces Actin Polymerization and Cytoskeletal Reorganization in Rolling Platelets and Glycoprotein Ib/V/IX-transfected Cells

    Yuping Yuan;Suhasini Kulkarni;Philippe Ulsemer;Susan L Cranmer

  • A new variant of Glanzmann's thrombasthenia (Strasbourg I). Platelets with functionally defective glycoprotein IIb-IIIa complexes and a glycoprotein IIIa 214Arg----214Trp mutation.

    F Lanza;A Stierlé;D Fournier;M Morales

  • Signaling Role for Phospholipase Cγ2 in Platelet Glycoprotein Ibα Calcium Flux and Cytoskeletal Reorganization INVOLVEMENT OF A PATHWAY DISTINCT FROM FcRγ CHAIN AND FcγRIIA

    Pierre Mangin;Yuping Yuan;Isaac Goncalves;Anita Eckly

  • Microparticles are new biomarkers of septic shock-induced disseminated intravascular coagulopathy

    Xavier Delabranche;Julie Boisramé-Helms;Pierre Asfar;Asaël Berger

  • Circulating procoagulant microparticles and soluble GPV in myocardial infarction treated by primary percutaneous transluminal coronary angioplasty. A possible role for GPIIb-IIIa antagonists

    Morel O;Hugel B;Jesel L;Mallat Z

  • Biogenesis of the demarcation membrane system (DMS) in megakaryocytes

    Anita Eckly;Harry Heijnen;Harry Heijnen;Fabien Pertuy;Willie Geerts

Frequent Co-Authors

Christian Gachet
Christian Gachet University of Strasbourg
Jean-Pierre Cazenave
Jean-Pierre Cazenave University of Strasbourg
Shaun P. Jackson
Shaun P. Jackson University of Sydney
Carsten Janke
Carsten Janke Institute Curie
Bernhard Nieswandt
Bernhard Nieswandt University of Würzburg
Eric Rubinstein
Eric Rubinstein Sorbonne University
Claude Boucheix
Claude Boucheix University of Paris-Saclay
Arnold Munnich
Arnold Munnich Necker-Enfants Malades Hospital

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