D-Index & Metrics Best Publications

D-Index & Metrics D-index (Discipline H-index) only includes papers and citation values for an examined discipline in contrast to General H-index which accounts for publications across all disciplines.

Discipline name D-index D-index (Discipline H-index) only includes papers and citation values for an examined discipline in contrast to General H-index which accounts for publications across all disciplines. Citations Publications World Ranking National Ranking
Medicine D-index 118 Citations 46,238 406 World Ranking 2308 National Ranking 1342

Research.com Recognitions

Awards & Achievements

Member of the Association of American Physicians

Overview

What is he best known for?

The fields of study he is best known for:

  • Gene
  • Enzyme
  • Platelet

Zaverio M. Ruggeri focuses on Platelet, Von Willebrand factor, Immunology, Platelet membrane glycoprotein and Molecular biology. His Platelet research includes elements of Hemostasis, Thrombus, Biophysics and Cell biology. The study incorporates disciplines such as Endocrinology and Biochemistry in addition to Von Willebrand factor.

His studies deal with areas such as Cell surface receptor, Integrin and Cancer research as well as Immunology. His Platelet membrane glycoprotein study incorporates themes from Phenotype, Alpha chain, Signal transduction, Binding site and Ristocetin. His Molecular biology research incorporates elements of Fibronectin, Protease, Epitope, Cell type and Monoclonal antibody.

His most cited work include:

  • Platelets in atherothrombosis. (1298 citations)
  • Initiation of Platelet Adhesion by Arrest onto Fibrinogen or Translocation on von Willebrand Factor (1005 citations)
  • Update on the pathophysiology and classification of von Willebrand disease: a report of the Subcommittee on von Willebrand Factor (818 citations)

What are the main themes of his work throughout his whole career to date?

Platelet, Von Willebrand factor, Molecular biology, Immunology and Biochemistry are his primary areas of study. His research in Platelet intersects with topics in Thrombus and Endocrinology. His Von Willebrand factor study combines topics from a wide range of disciplines, such as Hemostasis and Biophysics.

His Molecular biology research focuses on subjects like Antibody, which are linked to Antigen. His work carried out in the field of Immunology brings together such families of science as Disease and Cell biology. His Platelet membrane glycoprotein study integrates concerns from other disciplines, such as Peptide sequence and Binding site.

He most often published in these fields:

  • Platelet (62.66%)
  • Von Willebrand factor (53.49%)
  • Molecular biology (28.17%)

What were the highlights of his more recent work (between 2010-2020)?

  • Platelet (62.66%)
  • Cell biology (15.94%)
  • Thrombin (10.26%)

In recent papers he was focusing on the following fields of study:

The scientist’s investigation covers issues in Platelet, Cell biology, Thrombin, Von Willebrand factor and Immunology. Platelet is a subfield of Internal medicine that Zaverio M. Ruggeri investigates. The study incorporates disciplines such as Ex vivo, Integrin, Biochemistry and Tissue factor in addition to Cell biology.

His research investigates the link between Integrin and topics such as Molecular biology that cross with problems in Genetically modified mouse. His research integrates issues of Endothelial activation and Glycoprotein in his study of Von Willebrand factor. His biological study deals with issues like Pharmacology, which deal with fields such as Fibrinolytic agent.

Between 2010 and 2020, his most popular works were:

  • Antiplatelet therapy prevents hepatocellular carcinoma and improves survival in a mouse model of chronic hepatitis B (206 citations)
  • Immunosurveillance of the liver by intravascular effector CD8(+) T cells. (171 citations)
  • P2X7 receptor signaling contributes to tissue factor–dependent thrombosis in mice (119 citations)

In his most recent research, the most cited papers focused on:

  • Gene
  • Enzyme
  • Internal medicine

His primary scientific interests are in Cell biology, Platelet, Immunology, Receptor and Pathology. His Cell biology study combines topics in areas such as Platelet Glycoprotein GPIb-IX Complex, Biochemistry, Thrombin and Tissue factor. Zaverio M. Ruggeri is interested in Von Willebrand factor, which is a branch of Platelet.

His Von Willebrand factor research is multidisciplinary, incorporating elements of Extracellular matrix and Glycoprotein. In his work, Viremia, Virology, CD8, Antigen and CD44 is strongly intertwined with Cytotoxic T cell, which is a subfield of Immunology. Zaverio M. Ruggeri interconnects Inflammation and Metastasis in the investigation of issues within Receptor.

This overview was generated by a machine learning system which analysed the scientist’s body of work. If you have any feedback, you can contact us here.

Best Publications

Platelets in atherothrombosis

Zaverio M Ruggeri.
Nature Medicine (2002)

1957 Citations

Initiation of Platelet Adhesion by Arrest onto Fibrinogen or Translocation on von Willebrand Factor

Brian Savage;Enrique Saldívar;Zaverio M Ruggeri.
Cell (1996)

1510 Citations

Update on the pathophysiology and classification of von Willebrand disease: a report of the Subcommittee on von Willebrand Factor

J E Sadler;U Budde;J C J Eikenboom;E J Favaloro.
Journal of Thrombosis and Haemostasis (2006)

1227 Citations

Specific Synergy of Multiple Substrate–Receptor Interactions in Platelet Thrombus Formation under Flow

Brian Savage;Fanny Almus-Jacobs;Zaverio M Ruggeri.
Cell (1998)

1024 Citations

Adhesion Mechanisms in Platelet Function

Zaverio M. Ruggeri;G. Loredana Mendolicchio.
Circulation Research (2007)

759 Citations

1-DEAMINO-8-D-ARGININE VASOPRESSIN: A NEW PHARMACOLOGICAL APPROACH TO THE MANAGEMENT OF HAEMOPHILIA AND VON WILLEBRAND'S DISEASE

P.M. Mannucci;F.I. Pareti;Z.M. Ruggeri;Anna Capitanio.
The Lancet (1977)

751 Citations

Integrin activation controls metastasis in human breast cancer

Brunhilde Felding-Habermann;Timothy E. O'Toole;Jeffrey W. Smith;Emilia Fransvea.
Proceedings of the National Academy of Sciences of the United States of America (2001)

731 Citations

The complex multimeric composition of factor VIII/von Willebrand factor

Zaverio M. Ruggeri;Theodore S. Zimmerman.
Blood (1981)

725 Citations

Variant von Willebrand's Disease: CHARACTERIZATION OF TWO SUBTYPES BY ANALYSIS OF MULTIMERIC COMPOSITION OF FACTOR VIII/VON WILLEBRAND FACTOR IN PLASMA AND PLATELETS

Zaverio M. Ruggeri;Theodore S. Zimmerman.
Journal of Clinical Investigation (1980)

666 Citations

von Willebrand factor and von Willebrand disease [published erratum appears in Blood 1988 Mar;71(3):830]

ZM Ruggeri;TS Zimmerman.
Blood (1987)

612 Citations

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