Integrin, Cell biology, Platelet, Biochemistry and Platelet activation are his primary areas of study. His studies in Integrin integrate themes in fields like GTPase and Immunology. His research in Cell biology intersects with topics in Integrin alpha M, Cell adhesion and Cytoskeleton.
His Platelet research incorporates themes from Molecular biology, Biophysics, Fibrinogen and Cell surface receptor. His Biochemistry study frequently draws parallels with other fields, such as Thrombin. The Tyrosine phosphorylation study which covers Protein tyrosine phosphatase that intersects with Receptor tyrosine kinase.
His main research concerns Integrin, Cell biology, Platelet, Biochemistry and Molecular biology. His Integrin research is multidisciplinary, incorporating perspectives in Integrin alpha M and Cell adhesion. His research on Cell biology often connects related topics like Platelet Glycoprotein GPIIb-IIIa Complex.
His work in Platelet covers topics such as Endocrinology which are related to areas like Phospholipid. His study focuses on the intersection of Biochemistry and fields such as Biophysics with connections in the field of Membrane. The concepts of his Molecular biology study are interwoven with issues in Alpha, Chinese hamster ovary cell, Protein subunit, Beta and Monoclonal antibody.
His primary scientific interests are in Integrin, Cell biology, Platelet, Cancer research and Fibrinogen binding. His Integrin study incorporates themes from Endothelial stem cell, Actin cytoskeleton and Immunology. The various areas that he examines in his Cell biology study include Integrin, beta 6 and Cell adhesion.
His work carried out in the field of Platelet brings together such families of science as Fibrinogen, Proto-oncogene tyrosine-protein kinase Src, Tyrosine phosphorylation, Syk and Hemostasis. His biological study spans a wide range of topics, including Fibrinogen receptor and Ubiquitin, Ubiquitin ligase. His Biochemistry research focuses on subjects like Thrombin receptor, which are linked to Platelet activation, SKAP1 and Pharmacology.
Sanford J. Shattil mostly deals with Integrin, Cell biology, Focal adhesion, Integrin, beta 6 and Integrin alpha M. The study incorporates disciplines such as Biophysics, Signal transduction and Extracellular matrix assembly in addition to Integrin. Sanford J. Shattil combines subjects such as Bone growth and Phosphorylation with his study of Signal transduction.
His Cell biology research focuses on Molecular biology and how it connects with Second messenger system. His Focal adhesion study combines topics from a wide range of disciplines, such as Megakaryopoiesis, Cancer research and Platelet. His research integrates issues of Integrin alphaVbeta3, Collagen receptor, Alpha-v beta-3 and Tumor progression in his study of Integrin, beta 6.
This overview was generated by a machine learning system which analysed the scientist’s body of work. If you have any feedback, you can contact us here.
Talin Binding to Integrin ß Tails: A Final Common Step in Integrin Activation
Seiji Tadokoro;Sanford J. Shattil;Koji Eto;Vera Tai.
Science (2003)
Changes in the platelet membrane glycoprotein IIb.IIIa complex during platelet activation.
S J Shattil;J A Hoxie;M Cunningham;L F Brass.
Journal of Biological Chemistry (1985)
Detection of activated platelets in whole blood using activation- dependent monoclonal antibodies and flow cytometry
Sanford J. Shattil;Michael Cunningham;James A. Hoxie.
Blood (1987)
The final steps of integrin activation: the end game
Sanford J. Shattil;Chungho Kim;Mark H. Ginsberg.
Nature Reviews Molecular Cell Biology (2010)
Integrin Signaling: The Platelet Paradigm
Sanford J. Shattil;Hirokazu Kashiwagi;Nisar Pampori.
Blood (1998)
Complement proteins C5b-9 cause release of membrane vesicles from the platelet surface that are enriched in the membrane receptor for coagulation factor Va and express prothrombinase activity.
P J Sims;E M Faioni;T Wiedmer;S J Shattil.
Journal of Biological Chemistry (1988)
Integrin cytoplasmic domains mediate inside-out signal transduction
Timothy E. O'Toole;Yasuhiro Katagiri;Yasuhiro Katagiri;Randall J. Faull;Randall J. Faull;Karlheinz Peter;Karlheinz Peter.
Journal of Cell Biology (1994)
Assembly of the platelet prothrombinase complex is linked to vesiculation of the platelet plasma membrane. Studies in Scott syndrome: an isolated defect in platelet procoagulant activity.
P J Sims;T Wiedmer;C T Esmon;H J Weiss.
Journal of Biological Chemistry (1989)
Integrin activation controls metastasis in human breast cancer
Brunhilde Felding-Habermann;Timothy E. O'Toole;Jeffrey W. Smith;Emilia Fransvea.
Proceedings of the National Academy of Sciences of the United States of America (2001)
Breaking the Integrin Hinge A DEFINED STRUCTURAL CONSTRAINT REGULATES INTEGRIN SIGNALING
Paul E. Hughes;Federico Diaz-Gonzalez;Lilley Leong;Chuanyue Wu.
Journal of Biological Chemistry (1996)
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