David A. Calderwood mainly focuses on Cell biology, Integrin, Integrin, beta 6, CD49c and Integrin alpha M. His Cell biology research includes themes of Biochemistry, Cell adhesion and Filamin. His Cell adhesion study combines topics from a wide range of disciplines, such as Cell signaling, Signal transduction and Cytoskeleton.
The study incorporates disciplines such as Actin cytoskeleton and Focal adhesion in addition to Integrin. His CD49c research incorporates elements of ITGA6 and Phosphotyrosine binding. His work deals with themes such as Platelet Glycoprotein GPIIb-IIIa Complex and Rap1, which intersect with ITGA6.
His primary areas of study are Cell biology, Integrin, Integrin, beta 6, Cell adhesion and Focal adhesion. His study in Cell biology is interdisciplinary in nature, drawing from both Actin cytoskeleton, Filamin and Cytoskeleton. His study ties his expertise on Integrin alpha M together with the subject of Integrin.
He studies CD49c which is a part of Integrin, beta 6. David A. Calderwood has researched Cell adhesion in several fields, including Cytoplasm, Cell signaling, Signal transduction and Intracellular. His Focal adhesion study incorporates themes from Cell migration, Angiogenesis and Dynamin.
David A. Calderwood spends much of his time researching Cell biology, Integrin, Focal adhesion, Biophysics and Actin. His Cell biology study frequently draws connections between related disciplines such as Gene knockdown. His Integrin research integrates issues from Cell adhesion and Signal transducing adaptor protein.
His biological study spans a wide range of topics, including Cell morphology, Binding site and Cytoskeleton. His Biophysics study integrates concerns from other disciplines, such as Protein structure and Phalloidin. The concepts of his Actin study are interwoven with issues in FLNA and Filamin.
David A. Calderwood focuses on Integrin, Focal adhesion, Cell biology, Cytoskeleton and Actin. His work often combines Integrin and Integrin-linked kinase studies. His Focal adhesion study incorporates themes from Extracellular, Signal transducing adaptor protein and Transmembrane protein.
David A. Calderwood combines subjects such as Extracellular matrix, Biophysics, Cell adhesion and Intracellular with his study of Cytoskeleton. His Actin research integrates issues from FLNA, Filamin and Mutant. His FLNA study integrates concerns from other disciplines, such as Binding domain, Protein domain and Actin cytoskeleton.
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Talin binding to integrin beta tails: a final common step in integrin activation.
Seiji Tadokoro;Sanford J. Shattil;Koji Eto;Vera Tai.
Integrin signalling at a glance
David S. Harburger;David A. Calderwood.
Journal of Cell Science (2009)
The Talin Head Domain Binds to Integrin β Subunit Cytoplasmic Tails and Regulates Integrin Activation
David A. Calderwood;Roy Zent;Richard Grant;D. Jasper G. Rees.
Journal of Biological Chemistry (1999)
Integrin cytoplasmic domain-binding proteins.
S. Liu;D.A. Calderwood;M.H. Ginsberg.
Journal of Cell Science (2000)
Integrins and actin filaments: reciprocal regulation of cell adhesion and signaling.
David A. Calderwood;Sanford J. Shattil;Mark H. Ginsberg.
Journal of Biological Chemistry (2000)
Forces and Bond Dynamics in Cell Adhesion
Evan A. Evans;Evan A. Evans;David A. Calderwood.
Structural determinants of integrin recognition by talin
Begoña Garcı́a-Alvarez;José M de Pereda;David A Calderwood;Tobias S Ulmer.
Molecular Cell (2003)
The phosphotyrosine binding-like domain of talin activates integrins.
David A. Calderwood;Boxu Yan;Jose M. de Pereda;Begoña Garcı́a Alvarez.
Journal of Biological Chemistry (2002)
Reconstructing and Deconstructing Agonist-Induced Activation of Integrin αIIbβ3
Jaewon Han;Chinten James Lim;Naohide Watanabe;Alessandra Soriani.
Current Biology (2006)
Integrin β cytoplasmic domain interactions with phosphotyrosine-binding domains: A structural prototype for diversity in integrin signaling
David A. Calderwood;Yosuke Fujioka;Jose M. de Pereda;Begoña García-Alvarez.
Proceedings of the National Academy of Sciences of the United States of America (2003)
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