What is he best known for?
The fields of study he is best known for:
- Gene
- Cell membrane
- Signal transduction
David A. Calderwood mainly focuses on Cell biology, Integrin, Integrin, beta 6, CD49c and Integrin alpha M.
His Cell biology research includes themes of Biochemistry, Cell adhesion and Filamin.
His Cell adhesion study combines topics from a wide range of disciplines, such as Cell signaling, Signal transduction and Cytoskeleton.
The study incorporates disciplines such as Actin cytoskeleton and Focal adhesion in addition to Integrin.
His CD49c research incorporates elements of ITGA6 and Phosphotyrosine binding.
His work deals with themes such as Platelet Glycoprotein GPIIb-IIIa Complex and Rap1, which intersect with ITGA6.
His most cited work include:
- Talin binding to integrin beta tails: a final common step in integrin activation. (1033 citations)
- Integrin signalling at a glance (624 citations)
- The Talin Head Domain Binds to Integrin β Subunit Cytoplasmic Tails and Regulates Integrin Activation (615 citations)
What are the main themes of his work throughout his whole career to date?
His primary areas of study are Cell biology, Integrin, Integrin, beta 6, Cell adhesion and Focal adhesion.
His study in Cell biology is interdisciplinary in nature, drawing from both Actin cytoskeleton, Filamin and Cytoskeleton.
His study ties his expertise on Integrin alpha M together with the subject of Integrin.
He studies CD49c which is a part of Integrin, beta 6.
David A. Calderwood has researched Cell adhesion in several fields, including Cytoplasm, Cell signaling, Signal transduction and Intracellular.
His Focal adhesion study incorporates themes from Cell migration, Angiogenesis and Dynamin.
He most often published in these fields:
- Cell biology (79.46%)
- Integrin (66.07%)
- Integrin, beta 6 (27.68%)
What were the highlights of his more recent work (between 2017-2021)?
- Cell biology (79.46%)
- Integrin (66.07%)
- Focal adhesion (22.32%)
In recent papers he was focusing on the following fields of study:
David A. Calderwood spends much of his time researching Cell biology, Integrin, Focal adhesion, Biophysics and Actin.
His Cell biology study frequently draws connections between related disciplines such as Gene knockdown.
His Integrin research integrates issues from Cell adhesion and Signal transducing adaptor protein.
His biological study spans a wide range of topics, including Cell morphology, Binding site and Cytoskeleton.
His Biophysics study integrates concerns from other disciplines, such as Protein structure and Phalloidin.
The concepts of his Actin study are interwoven with issues in FLNA and Filamin.
Between 2017 and 2021, his most popular works were:
- Structural basis of the filamin A actin-binding domain interaction with F-actin. (30 citations)
- Chapter 22: Structural and signaling functions of integrins. (24 citations)
- Kindlin-2 interacts with a highly conserved surface of ILK to regulate focal adhesion localization and cell spreading. (18 citations)
In his most recent research, the most cited papers focused on:
- Gene
- Cell membrane
- Signal transduction
David A. Calderwood focuses on Integrin, Focal adhesion, Cell biology, Cytoskeleton and Actin.
His work often combines Integrin and Integrin-linked kinase studies.
His Focal adhesion study incorporates themes from Extracellular, Signal transducing adaptor protein and Transmembrane protein.
David A. Calderwood combines subjects such as Extracellular matrix, Biophysics, Cell adhesion and Intracellular with his study of Cytoskeleton.
His Actin research integrates issues from FLNA, Filamin and Mutant.
His FLNA study integrates concerns from other disciplines, such as Binding domain, Protein domain and Actin cytoskeleton.
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