World's Best Scientists 2026 revealed!

D-Index & Metrics

Biology and Biochemistry

D-Index
64
Citations
13758
World Ranking
9735
National Ranking
4286

Overview

Roy Zent is affiliated with Vanderbilt University Medical Center in the United States. Their research spans the intersecting fields of Medicine and Biochemistry, Genetics and Molecular Biology, with a particular focus on Molecular Biology, Immunology and Allergy, Nephrology, Immunology, and Cell Biology.

The scientist's work centers on several main topics, including:

  • Renal and related cancers
  • Cell Adhesion Molecules Research
  • Renal Diseases and Glomerulopathies
  • Adipose Tissue and Metabolism
  • Cellular Mechanics and Interactions
  • Chronic Kidney Disease and Diabetes
  • Immune cells in cancer

Among recent publications led or co-authored by Roy Zent are:

  • "Basement membrane ligands initiate distinct signalling networks to direct cell shape," 2020, Matrix Biology
  • "DDR1 contributes to kidney inflammation and fibrosis by promoting the phosphorylation of BCR and STAT3," 2021, JCI Insight
  • "Cyclin G1 induces maladaptive proximal tubule cell dedifferentiation and renal fibrosis through CDK5 activation," 2022, Journal of Clinical Investigation
  • "Small proline-rich repeat 3 is a novel coordinator of PDGFRβ and integrin β1 crosstalk to augment proliferation and matrix synthesis by cardiac fibroblasts," 2020, The FASEB Journal
  • "Electronic Data Capture System (REDCap) for Health Care Research and Training in a Resource-Constrained Environment: Technology Adoption Case Study," 2022, JMIR Medical Informatics

Frequent publication venues for their research include:

  • Journal of the American Society of Nephrology
  • bioRxiv (Cold Spring Harbor Laboratory)
  • JCI Insight
  • Diabetes
  • Matrix Biology

Collaborations feature recurring co-authors such as Ambra Pozzi, Fabian Bock, Xinyu Dong, Olga M. Viquez, and Raymond C. Harris, indicating ongoing partnerships in related research domains.

Best Publications

  • The Tail of Integrins, Talin, and Kindlins

    Markus Moser;Kyle R. Legate;Roy Zent;Reinhard Fässler

  • The Talin head domain binds to integrin beta subunit cytoplasmic tails and regulates integrin activation.

    D. A. Calderwood;R. Zent;R. Grant;D. J. G. Rees

  • Integrin β1 Signaling Is Necessary for Transforming Growth Factor-β Activation of p38MAPK and Epithelial Plasticity

    Neil A. Bhowmick;Roy Zent;Roy Zent;Mayshan Ghiassi;Maureen McDonnell

  • Kindlin-2 controls bidirectional signaling of integrins

    Eloi Montanez;Siegfried Ussar;Martina Schifferer;Michael Bösl

  • Extracellular rigidity sensing by talin isoform-specific mechanical linkages.

    Katharina Austen;Pia Ringer;Alexander Mehlich;Anna Chrostek-Grashoff

  • Sirt1 activation protects the mouse renal medulla from oxidative injury

    Wenjuan He;Yingying Wang;Ming-Zhi Zhang;Li You

  • Kindlin-2 cooperates with talin to activate integrins and induces cell spreading by directly binding paxillin

    Marina Theodosiou;Moritz Widmaier;Ralph T Böttcher;Emanuel Rognoni

  • Vinculin controls talin engagement with the actomyosin machinery.

    Paul Atherton;Ben Stutchbury;De Yao Wang;Devina Jethwa

  • Characterization of 5,6- and 8,9-Epoxyeicosatrienoic Acids (5,6- and 8,9-EET) as Potent in Vivo Angiogenic Lipids

    Ambra Pozzi;Ines Macias-Perez;Tristin Abair;Shouzuo Wei

  • β1 integrin expression by podocytes is required to maintain glomerular structural integrity

    Ambra Pozzi;George Jarad;Gilbert W. Moeckel;Sergio Coffa

  • Global Analysis Reveals the Complexity of the Human Glomerular Extracellular Matrix

    Rachel Lennon;Rachel Lennon;Adam Byron;Jonathan D. Humphries;Michael J. Randles;Michael J. Randles

  • Activated type I TGFβ receptor kinase enhances the survival of mammary epithelial cells and accelerates tumor progression

    R S Muraoka-Cook;I Shin;I Shin;J Y Yi;E Easterly

  • αvβ3 and αvβ5 Integrins Bind Both the Proximal RGD Site and Non-RGD Motifs within Noncollagenous (NC1) Domain of the α3 Chain of Type IV Collagen: IMPLICATION FOR THE MECHANISM OF ENDOTHELIAL CELL ADHESION

    Vadim Pedchenko;Roy Zent;Billy G. Hudson

  • Salt-sensitive hypertension is associated with dysfunctional Cyp4a10 gene and kidney epithelial sodium channel

    Kiyoshi Nakagawa;Vijaykumar R. Holla;Yuan Wei;Wen-Hui Wang

  • Distinct Domains of CD98hc Regulate Integrins and Amino Acid Transport

    Csilla A. Fenczik;Roy Zent;Melissa Dellos;David A. Calderwood

  • Transforming Growth Factor β Induces Clustering of HER2 and Integrins by Activating Src-Focal Adhesion Kinase and Receptor Association to the Cytoskeleton

    Shizhen Emily Wang;Bin Xiang;Roy Zent;Vito Quaranta

  • Podocyte-associated talin1 is critical for glomerular filtration barrier maintenance

    Xuefei Tian;Jin Ju Kim;Susan M. Monkley;Nanami Gotoh

  • Integrin-linked kinase is an adaptor with essential functions during mouse development.

    Anika Lange;Sara A. Wickström;Madis Jakobson;Roy Zent

  • Prostaglandin E2-EP4 receptor promotes endothelial cell migration via ERK activation and angiogenesis in vivo.

    Reena Rao;Reyadh Redha;Ines Macias-Perez;Yan Su

  • Integrins in Kidney Disease

    Ambra Pozzi;Roy Zent

Frequent Co-Authors

Ambra Pozzi
Ambra Pozzi Vanderbilt University Medical Center
Raymond C. Harris
Raymond C. Harris Vanderbilt University Medical Center
Reinhard Fässler
Reinhard Fässler Max Planck Society
Billy G. Hudson
Billy G. Hudson Vanderbilt University Medical Center
Charles R. Sanders
Charles R. Sanders Vanderbilt University
Vito Quaranta
Vito Quaranta Vanderbilt University
Timothy S. Blackwell
Timothy S. Blackwell University of Michigan–Ann Arbor
Harold L. Moses
Harold L. Moses Vanderbilt University
Matthew D. Breyer
Matthew D. Breyer Eli Lilly (United States)
Carlos L. Arteaga
Carlos L. Arteaga The University of Texas Southwestern Medical Center

If you think any of the details on this page are incorrect, let us know.

Report an issue

We appreciate your kind effort to assist us to improve this page, it would be helpful providing us with as much detail as possible in the text box below:

Related Online Degrees & Career Pathways

Students interested in Biology and Biochemistry often explore a wide range of related degrees and professional pathways in healthcare and science. Online learning opportunities have expanded, offering both affordability and flexibility for those balancing studies with other commitments.

For those seeking fast entry into healthcare, online radiology tech programs offer an accessible route to begin working with diagnostic technology in hospitals or clinics. Aspiring nutrition specialists can pursue one of the top dietetics masters programs to deepen their knowledge and qualify for advanced roles in dietetics and nutrition science.

Those looking for a versatile healthcare position may benefit from enrolling in medical assistant programs online Michigan, which prepare students for essential clinical and administrative roles. Medical assistants seeking career advancement can further build on their credentials through a ma to lpn bridge program, preparing them for licensed practical nurse (LPN) roles.

Overall, online degrees and bridge programs in these fields offer strong job prospects, diverse specialty options, and pathways to higher-paying, in-demand healthcare careers.

Best Scientists Citing Roy Zent

Trending Scientists

Recently Published Articles