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D-Index & Metrics

Chemistry

D-Index
58
Citations
11945
World Ranking
10620
National Ranking
2928

Overview

Charles R. Sanders is affiliated with Vanderbilt University in the United States. Their research spans multiple areas within biochemistry, genetics, and molecular biology, with an emphasis on molecular biology and its related disciplines. The scientist's work also contributes to fields including medicine, with notable attention to cardiology and cardiovascular medicine, cellular and molecular neuroscience, cell biology, and physiology.

The primary research topics Charles R. Sanders focuses on include:

  • Cardiac electrophysiology and arrhythmias
  • Ion channel regulation and function
  • Lipid membrane structure and behavior
  • Protein structure and dynamics
  • Hereditary neurological disorders
  • Cellular transport and secretion
  • RNA and protein synthesis mechanisms

Their scholarly output is published extensively in various scientific journals. Frequent publication venues for their research include:

  • Biophysical Journal
  • bioRxiv (Cold Spring Harbor Laboratory)
  • Journal of Biological Chemistry
  • Proceedings of the National Academy of Sciences
  • Membranes

Their recent scientific papers include:

  • "Structure and physiological function of the human KCNQ1 channel voltage sensor intermediate state," 2020, eLife
  • "Peripheral myelin protein 22 preferentially partitions into ordered phase membrane domains," 2020, Proceedings of the National Academy of Sciences
  • "Bicelles Rich in both Sphingolipids and Cholesterol and Their Use in Studies of Membrane Proteins," 2020, Journal of the American Chemical Society
  • "Allosteric mechanism for KCNE1 modulation of KCNQ1 potassium channel activation," 2020, eLife
  • "Structures Illuminate Cardiac Ion Channel Functions in Health and in Long QT Syndrome," 2020, Frontiers in Pharmacology

Collaboration features prominently in their research career, with the most frequent co-authors being:

  • Jens Meiler
  • Alfred L. George
  • Georg Kuenze
  • Carlos G. Vanoye
  • Gary A. Lorigan

Best Publications

  • Characterization of magnetically orientable bilayers in mixtures of dihexanoylphosphatidylcholine and dimyristoylphosphatidylcholine by solid-state NMR.

    Charles R. Sanders;James P. Schwonek

  • The Amyloid Precursor Protein Has a Flexible Transmembrane Domain and Binds Cholesterol

    Paul J. Barrett;Yuanli Song;Wade D. Van Horn;Eric J. Hustedt

  • Magnetically-oriented phospholipid micelles as a tool for the study of membrane-associated molecules

    Charles R. Sanders;Brian J. Hare;Kathleen P. Howard;James H. Prestegard

  • Reconstitution of Membrane Proteins into Lipid-Rich Bilayered Mixed Micelles for NMR Studies

    Charles R. Sanders;Geoffrey C. Landis

  • Bicelles: a model membrane system for all seasons?

    Charles R Sanders;R Scott Prosser

  • A sulfilimine bond identified in collagen IV.

    Roberto Vanacore;Amy-Joan L. Ham;Markus Voehler;Charles R. Sanders

  • Substrate Specificity of γ-Secretase and Other Intramembrane Proteases

    Andrew J. Beel;Charles R. Sanders

  • Disease-Related Misassembly of Membrane Proteins

    Charles R. Sanders;Jeffrey K. Myers

  • Magnetically orientable phospholipid bilayers containing small amounts of a bile salt analogue, CHAPSO

    C.R. Sanders;J.H. Prestegard

  • Solution NMR of membrane proteins: practice and challenges.

    Charles R. Sanders;Frank Sönnichsen

  • Folding and Misfolding of Human Membrane Proteins in Health and Disease: From Single Molecules to Cellular Proteostasis

    Justin T Marinko;Hui Huang;Wesley D Penn;John A Capra

  • Solution Nuclear Magnetic Resonance Structure of Membrane-Integral Diacylglycerol Kinase

    Wade D. Van Horn;Hak Jun Kim;Charles D. Ellis;Arina Hadziselimovic

  • Structure of KCNE1 and Implications for How It Modulates the KCNQ1 Potassium Channel

    Congbao Kang;Changlin Tian;Frank D. Sönnichsen;Jarrod A. Smith

  • Polypeptide variants of beta-arrestin and arrestin3.

    R Sterne-Marr;V V Gurevich;P Goldsmith;R C Bodine

  • Structural Studies of the Transmembrane C-Terminal Domain of the Amyloid Precursor Protein (APP): Does APP Function as a Cholesterol Sensor?,

    Andrew J. Beel;Charles K. Mobley;Hak Jun Kim;Fang Tian

  • Direct binding of cholesterol to the amyloid precursor protein: An important interaction in lipid-Alzheimer's disease relationships?

    Andrew J. Beel;Masayoshi Sakakura;Paul J. Barrett;Charles R. Sanders

  • Cholesterol as a co-solvent and a ligand for membrane proteins

    Yuanli Song;Anne K. Kenworthy;Charles R. Sanders

  • Recent Advances in the Application of Solution NMR Spectroscopy to Multi-Span Integral Membrane Proteins.

    Hak Jun Kim;Stanley C. Howell;Wade D. Van Horn;Young Ho Jeon

  • On choosing a detergent for solution NMR studies of membrane proteins

    Olga Vinogradova;Frank Sönnichsen;Charles R. Sanders

  • DEER EPR Measurements for Membrane Protein Structures via Bifunctional Spin Labels and Lipodisq Nanoparticles

    Indra D. Sahu;Robert M. McCarrick;Kaylee R. Troxel;Rongfu Zhang

  • Misfolding of membrane proteins in health and disease: the lady or the tiger?

    Charles R Sanders;Joanna K Nagy

  • Customizing model membranes and samples for NMR spectroscopic studies of complex membrane proteins.

    Charles R Sanders;Kirill Oxenoid

Frequent Co-Authors

Jens Meiler
Jens Meiler Vanderbilt University
Alfred L. George
Alfred L. George Northwestern University
Roy Zent
Roy Zent Vanderbilt University Medical Center
Frank D. Sönnichsen
Frank D. Sönnichsen Kiel University
Ambra Pozzi
Ambra Pozzi Vanderbilt University Medical Center
James H. Prestegard
James H. Prestegard University of Georgia
Reinhard Fässler
Reinhard Fässler Max Planck Society
Vsevolod V. Gurevich
Vsevolod V. Gurevich Vanderbilt University
Richard M. Breyer
Richard M. Breyer Vanderbilt University Medical Center
Bruce D. Carter
Bruce D. Carter Vanderbilt University

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