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Chemistry

D-Index
75
Citations
16346
World Ranking
4553
National Ranking
1434

Research.com Recognitions

  • 1988 - Fellow of Alfred P. Sloan Foundation

Overview

Timothy A. Cross is primarily affiliated with Florida State University in the United States. Their research work is situated within the broad field of Biochemistry, Genetics and Molecular Biology, with a specific focus on Molecular Biology, Spectroscopy, Infectious Diseases, Ecology, and Genetics.

The scientist's research topics encompass a range of areas including Advanced NMR Techniques and Applications, Protein Structure and Dynamics, RNA and protein synthesis mechanisms, Tuberculosis Research and Epidemiology, Bacteriophages and microbial interactions, Lipid Membrane Structure and Behavior, and Bacterial Genetics and Biotechnology.

Timothy A. Cross has contributed to several recent papers, which include:

  • Functional stability of water wire-carbonyl interactions in an ion channel (2020), Proceedings of the National Academy of Sciences
  • Observation of the Imidazole-Imidazolium Hydrogen Bonds Responsible for Selective Proton Conductance in the Influenza A M2 Channel (2020), Journal of the American Chemical Society
  • Fuzzy Association of an Intrinsically Disordered Protein with Acidic Membranes (2020), JACS Au
  • Sequence-Dependent Correlated Segments in the Intrinsically Disordered Region of ChiZ (2020), Biomolecules
  • Surprising Rigidity of Functionally Important Water Molecules Buried in the Lipid Headgroup Region (2022), Journal of the American Chemical Society

Their frequent co-authors include Huan-Xiang Zhou, Riqiang Fu, Cristian A. Escobar, Rongfu Zhang, and Huajun Qin. These collaborations have resulted in multiple publications across several well-known scientific journals.

Timothy A. Cross has published extensively in the following venues:

  • bioRxiv (Cold Spring Harbor Laboratory)
  • Journal of the American Chemical Society
  • Communications Biology
  • Biophysical Journal
  • Abstracts

Among awards, they have been recognized as a Fellow of the Alfred P. Sloan Foundation, an honor received in 1988.

Best Publications

  • High-resolution conformation of gramicidin A in a lipid bilayer by solid-state NMR

    RR Ketchem;W Hu;TA Cross

  • Insight into the Mechanism of the Influenza A Proton Channel from a Structure in a Lipid Bilayer

    Mukesh Sharma;Myunggi Yi;Hao Dong;Huajun Qin

  • Imaging Membrane Protein Helical Wheels

    J. Wang;J. Denny;C. Tian;S. Kim

  • High-resolution polypeptide structure in a lamellar phase lipid environment from solid state NMR derived orientational constraints

    RR Ketchem;B Roux;TA Cross

  • Influences of Membrane Mimetic Environments on Membrane Protein Structures

    Huan-Xiang Zhou;Timothy A. Cross

  • Structure of the transmembrane region of the M2 protein H(+) channel.

    Junfeng Wang;Sanguk Kim;Frank Kovacs;Timothy A. Cross

  • Histidines, heart of the hydrogen ion channel from influenza A virus: toward an understanding of conductance and proton selectivity.

    Jun Hu;Riqiang Fu;Katsuyuki Nishimura;Li Zhang

  • Volume-selective excitation. A novel approach to topical NMR

    W.P Aue;S Müller;T.A Cross;J Seelig

  • Solid-state NMR structural studies of peptides and proteins in membranes

    T.A. Cross;S.J. Opella

  • Tryptophans in membrane proteins: indole ring orientations and functional implications in the gramicidin channel.

    Hu W;Lee Kc;Cross Ta

  • The closed state of a H+ channel helical bundle combining precise orientational and distance restraints from solid state NMR.

    Katsuyuki Nishimura;Sanguk Kim;Li Zhang;T A Cross

  • Detection of individual carbon resonances in solid proteins

    S. J. Opella;M. H. Frey;T. A. Cross

  • Influence of Solubilizing Environments on Membrane Protein Structures

    Timothy A. Cross;Mukesh Sharma;Myunggi Yi;Huan-Xiang Zhou

  • Backbone Structure of the Amantadine-Blocked Trans-Membrane Domain M2 Proton Channel from Influenza A Virus

    Jun Hu;Tom Asbury;Srisairam Achuthan;Conggang Li

  • Transmembrane four-helix bundle of influenza A M2 protein channel: structural implications from helix tilt and orientation

    F.A. Kovacs;T.A. Cross

  • NMR spectroscopy up to 35.2 T using a series-connected hybrid magnet

    Zhehong Gan;Ivan Hung;Xiaoling Wang;Joana Paulino

  • Macromolecular Structural Elucidation with Solid-State NMR-Derived Orientational Constraints.

    R. R. Ketchem;K. C. Lee;S. Huo;T. A. Cross

  • Helix tilt of the M2 transmembrane peptide from influenza A virus: an intrinsic property.

    F.A. Kovacs;Jeffrey K. Denny;Z. Song;J.R. Quine

  • Perturbations of Native Membrane Protein Structure in Alkyl Phosphocholine Detergents: A Critical Assessment of NMR and Biophysical Studies

    Christophe Chipot;François Dehez;Jason R Schnell;Nicole Zitzmann

  • Initial structural and dynamic characterization of the M2 protein transmembrane and amphipathic helices in lipid bilayers.

    Changlin Tian;Philip Fei Gao;Lawrence H. Pinto;Robert A. Lamb

  • Gramicidin cation channel: an experimental determination of the right-handed helix sense and verification of beta-type hydrogen bonding.

    L K Nicholson;T A Cross

  • Magnetic ordering of phospholipid membranes

    Joachim Seelig;François Borle;Timothy A. Cross

Frequent Co-Authors

Riqiang Fu
Riqiang Fu Florida State University
Huan-Xiang Zhou
Huan-Xiang Zhou University of Illinois at Chicago
Ivan Hung
Ivan Hung University of Hong Kong
Stanley J. Opella
Stanley J. Opella University of California, San Diego
Eduard Y. Chekmenev
Eduard Y. Chekmenev Wayne State University
Richard Bertram
Richard Bertram Florida State University
Joachim Seelig
Joachim Seelig University of Basel
Tetsuo Asakura
Tetsuo Asakura Tokyo University of Agriculture and Technology
Robert A. Lamb
Robert A. Lamb Northwestern University
Eric J. Rubin
Eric J. Rubin Harvard University

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