Lawrence H. Pinto

Overview

Best Publications

• Mutagenesis and Mapping of a Mouse Gene, Clock, Essential for Circadian Behavior

  Martha Hotz Vitaterna;David P. King;Anne-Marie Chang;Jon M. Kornhauser

  2051
  Citations

• Influenza virus M2 protein has ion channel activity.

  Lawrence H. Pinto;Leslie J. Holsinger;Robert A. Lamb;Robert A. Lamb

  1635
  Citations

• Functional Identification of the Mouse Circadian Clock Gene by Transgenic BAC Rescue

  Marina P. Antoch;Eun Joo Song;Anne Marie Chang;Martha Hotz Vitaterna

  900
  Citations

• A functionally defined model for the M2 proton channel of influenza A virus suggests a mechanism for its ion selectivity.

  Lawrence H. Pinto;Gregg R. Dieckmann;Chris S. Gandhi;Carol G. Papworth

  532
  Citations

• Influenza A virus M2 ion channel protein: a structure-function analysis.

  Leslie J. Holsinger;Deepali Nichani;Lawrence H. Pinto;Robert A. Lamb

  397
  Citations

• Forward and reverse genetic approaches to behavior in the mouse

  Joseph S. Takahashi;Lawrence H. Pinto;Martha Hotz Vitaterna

  348
  Citations

• The gate of the influenza virus M2 proton channel is formed by a single tryptophan residue.

  Yajun Tang;Florina Zaitseva;Robert A. Lamb;Lawrence H. Pinto

  335
  Citations

• Influenza A Virus M2 Ion Channel Activity Is Essential for Efficient Replication in Tissue Culture

  Makoto Takeda;Andrew Pekosz;Kevin Shuck;Lawrence H. Pinto

  320
  Citations

• Structure and mechanism of proton transport through the transmembrane tetrameric M2 protein bundle of the influenza A virus.

  Rudresh Acharya;Vincenzo Carnevale;Giacomo Fiorin;Benjamin G. Levine

  286
  Citations

• Influenza Virus M2 Ion Channel Protein Is Necessary for Filamentous Virion Formation

  Jeremy S. Rossman;Xianghong Jing;Xianghong Jing;George P. Leser;Victoria Balannik

  255
  Citations

• Structure and inhibition of the drug-resistant S31N mutant of the M2 ion channel of influenza A virus

  Jun Wang;Yibing Wu;Chunlong Ma;Giacomo Fiorin

  249
  Citations

• The active oligomeric state of the minimalistic influenza virus M2 ion channel is a tetramer

  Takemasa Sakaguchi;Qiang Tu;Lawrence H. Pinto;Robert A. Lamb

  230
  Citations

• Influenza B Virus BM2 Protein Has Ion Channel Activity that Conducts Protons across Membranes

  Jorgen A Mould;Reay G Paterson;Makoto Takeda;Makoto Takeda;Yuki Ohigashi

  220
  Citations

• Functional studies indicate amantadine binds to the pore of the influenza A virus M2 proton-selective ion channel

  Xianghong Jing;Chunlong Ma;Yuki Ohigashi;Fernando A. Oliveira

  209
  Citations

• The mouse Clock mutation behaves as an antimorph and maps within the W19H deletion, distal of Kit.

  David P. King;Martha Hotz Vitaterna;Anne Marie Chang;William F. Dove

  199
  Citations

• Mechanism for Proton Conduction of the M2 Ion Channel of Influenza A Virus

  Jorgen A. Mould;Hui Chun Li;Christine S. Dudlak;James D. Lear

  192
  Citations

• Identification of the functional core of the influenza A virus A/M2 proton-selective ion channel

  Chunlong Ma;Alexei L. Polishchuk;Yuki Ohigashi;Amanda L. Stouffer;Amanda L. Stouffer

  184
  Citations

• Permeation and activation of the M2 ion channel of influenza A virus.

  Jorgen A. Mould;Jason E. Drury;Stephan M. Frings;U. Benjamin Kaupp

  182
  Citations

• Cu(II) inhibition of the proton translocation machinery of the influenza A virus M2 protein.

  Chris S. Gandhi;Kevin Shuck;James D. Lear;Gregg R. Dieckmann

  175
  Citations

• Analysis of the posttranslational modifications of the influenza virus M2 protein.

  Leslie J. Holsinger;Margaret A. Shaughnessy;Aurelia Micko;Lawrence H. Pinto

  173
  Citations