D-Index & Metrics Best Publications

D-Index & Metrics D-index (Discipline H-index) only includes papers and citation values for an examined discipline in contrast to General H-index which accounts for publications across all disciplines.

Discipline name D-index D-index (Discipline H-index) only includes papers and citation values for an examined discipline in contrast to General H-index which accounts for publications across all disciplines. Citations Publications World Ranking National Ranking
Immunology D-index 46 Citations 8,196 135 World Ranking 3055 National Ranking 47

Overview

What is he best known for?

The fields of study he is best known for:

  • Gene
  • Virus
  • DNA

Xavier Saelens spends much of his time researching Virology, Virus, Cell biology, Influenza A virus and Molecular biology. His Virology study combines topics in areas such as Epitope, Receptor, Immunology and Immunity. His Virus study incorporates themes from Pandemic, Microbiology and Vaccination.

Xavier Saelens combines subjects such as Apoptosis and Programmed cell death with his study of Cell biology. His study on Antigenic shift is often connected to Heterosubtypic immunity as part of broader study in Influenza A virus. His biological study spans a wide range of topics, including Jurkat cells, Translation, Eukaryotic translation, Antibody and Protein kinase domain.

His most cited work include:

  • Toxic proteins released from mitochondria in cell death (725 citations)
  • A universal influenza A vaccine based on the extracellular domain of the M2 protein. (691 citations)
  • The role of mitochondrial factors in apoptosis: a Russian roulette with more than one bullet. (505 citations)

What are the main themes of his work throughout his whole career to date?

His primary areas of investigation include Virology, Virus, Influenza A virus, Immunology and Antibody. His studies deal with areas such as Epitope, Monoclonal antibody and Immune system as well as Virology. As a part of the same scientific study, he usually deals with the Virus, concentrating on Vaccination and frequently concerns with Immunization.

His work in Influenza A virus tackles topics such as Ectodomain which are related to areas like Protein structure. His Antibody study combines topics from a wide range of disciplines, such as Molecular biology and Fusion protein. The Molecular biology study combines topics in areas such as Caspase, Jurkat cells, Apoptosis and Cell biology.

He most often published in these fields:

  • Virology (50.00%)
  • Virus (41.04%)
  • Influenza A virus (29.25%)

What were the highlights of his more recent work (between 2018-2021)?

  • Virology (50.00%)
  • Virus (41.04%)
  • Antibody (24.53%)

In recent papers he was focusing on the following fields of study:

Virology, Virus, Antibody, Immune system and Immunology are his primary areas of study. His study in Virology concentrates on Influenza A virus and Viral replication. In the subject of general Influenza A virus, his work in M1 protein is often linked to Haematopoiesis, thereby combining diverse domains of study.

His study in Virus focuses on Influenza vaccine in particular. As part of one scientific family, he deals mainly with the area of Immune system, narrowing it down to issues related to the Vaccination, and often Immunization and Adjuvant. The concepts of his Immunology study are interwoven with issues in Cytotoxic T cell and Function.

Between 2018 and 2021, his most popular works were:

  • Structural Basis for Potent Neutralization of Betacoronaviruses by Single-Domain Camelid Antibodies. (266 citations)
  • STAT2 signaling restricts viral dissemination but drives severe pneumonia in SARS-CoV-2 infected hamsters. (51 citations)
  • Erratum: Structural Basis for Potent Neutralization of Betacoronaviruses by Single-Domain Camelid Antibodies (Cell (2020) 181(5) (1004–1015.e15), (S0092867420304943), (10.1016/j.cell.2020.04.031)) (44 citations)

In his most recent research, the most cited papers focused on:

  • Gene
  • Virus
  • DNA

His scientific interests lie mostly in Virus, Virology, Antibody, Neutralization and Viral replication. His Virus study deals with the bigger picture of Immunology. His Virology research includes themes of Monoclonal antibody, Immunity and Drug resistance.

The study incorporates disciplines such as Receptor, Protein domain and Betacoronavirus in addition to Antibody. His Neutralization research integrates issues from Cell, Lipid bilayer fusion, Cell biology, Camelid and Coronavirus. His Viral replication study deals with Viral matrix protein intersecting with Protein filament.

This overview was generated by a machine learning system which analysed the scientist’s body of work. If you have any feedback, you can contact us here.

Best Publications

Toxic proteins released from mitochondria in cell death

Xavier Saelens;Nele Festjens;Lieselotte Vande Walle;Maria van Gurp.
Oncogene (2004)

1228 Citations

A universal influenza A vaccine based on the extracellular domain of the M2 protein.

Sabine Neirynck;Tom Deroo;Xavier Saelens;Peter Vanlandschoot.
Nature Medicine (1999)

1081 Citations

The role of mitochondrial factors in apoptosis: a Russian roulette with more than one bullet.

G van Loo;X Saelens;M van Gurp;M MacFarlane.
Cell Death & Differentiation (2002)

772 Citations

Mitochondrial intermembrane proteins in cell death.

Maria van Gurp;Nele Festjens;Geert van Loo;Xavier Saelens.
Biochemical and Biophysical Research Communications (2003)

522 Citations

Alice in caspase land. A phylogenetic analysis of caspases from worm to man.

Mohamed Lamkanfi;Wim Declercq;Michaël Kalai;Xavier Saelens.
Cell Death & Differentiation (2002)

422 Citations

Universal Vaccine Based on Ectodomain of Matrix Protein 2 of Influenza A: Fc Receptors and Alveolar Macrophages Mediate Protection

Karim El Bakkouri;Francis Descamps;Marina De Filette;Anouk Smet.
Journal of Immunology (2011)

374 Citations

Universal M2 ectodomain-based influenza A vaccines: preclinical and clinical developments

Michael Schotsaert;Marina De Filette;Walter Fiers;Xavier Saelens.
Expert Review of Vaccines (2009)

269 Citations

Structural Basis for Potent Neutralization of Betacoronaviruses by Single-Domain Camelid Antibodies.

Daniel Wrapp;Dorien De Vlieger;Kizzmekia S. Corbett;Gretel M. Torres.
Cell (2020)

267 Citations

M2e-based universal influenza A vaccine.

Lei Deng;Ki Joon Cho;Walter Fiers;Xavier Saelens.
Vaccine (2009)

257 Citations

Correction: Corrigendum: Potent single-domain antibodies that arrest respiratory syncytial virus fusion protein in its prefusion state

Iebe Rossey;Morgan S. A. Gilman;Stephanie C. Kabeche;Koen Sedeyn.
Nature Communications (2017)

241 Citations

Editorial Boards

Vaccine
(Impact Factor: 4.169)

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