Xavier Saelens spends much of his time researching Virology, Virus, Cell biology, Influenza A virus and Molecular biology. His Virology study combines topics in areas such as Epitope, Receptor, Immunology and Immunity. His Virus study incorporates themes from Pandemic, Microbiology and Vaccination.
Xavier Saelens combines subjects such as Apoptosis and Programmed cell death with his study of Cell biology. His study on Antigenic shift is often connected to Heterosubtypic immunity as part of broader study in Influenza A virus. His biological study spans a wide range of topics, including Jurkat cells, Translation, Eukaryotic translation, Antibody and Protein kinase domain.
His primary areas of investigation include Virology, Virus, Influenza A virus, Immunology and Antibody. His studies deal with areas such as Epitope, Monoclonal antibody and Immune system as well as Virology. As a part of the same scientific study, he usually deals with the Virus, concentrating on Vaccination and frequently concerns with Immunization.
His work in Influenza A virus tackles topics such as Ectodomain which are related to areas like Protein structure. His Antibody study combines topics from a wide range of disciplines, such as Molecular biology and Fusion protein. The Molecular biology study combines topics in areas such as Caspase, Jurkat cells, Apoptosis and Cell biology.
Virology, Virus, Antibody, Immune system and Immunology are his primary areas of study. His study in Virology concentrates on Influenza A virus and Viral replication. In the subject of general Influenza A virus, his work in M1 protein is often linked to Haematopoiesis, thereby combining diverse domains of study.
His study in Virus focuses on Influenza vaccine in particular. As part of one scientific family, he deals mainly with the area of Immune system, narrowing it down to issues related to the Vaccination, and often Immunization and Adjuvant. The concepts of his Immunology study are interwoven with issues in Cytotoxic T cell and Function.
His scientific interests lie mostly in Virus, Virology, Antibody, Neutralization and Viral replication. His Virus study deals with the bigger picture of Immunology. His Virology research includes themes of Monoclonal antibody, Immunity and Drug resistance.
The study incorporates disciplines such as Receptor, Protein domain and Betacoronavirus in addition to Antibody. His Neutralization research integrates issues from Cell, Lipid bilayer fusion, Cell biology, Camelid and Coronavirus. His Viral replication study deals with Viral matrix protein intersecting with Protein filament.
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Toxic proteins released from mitochondria in cell death
Xavier Saelens;Nele Festjens;Lieselotte Vande Walle;Maria van Gurp.
Oncogene (2004)
A universal influenza A vaccine based on the extracellular domain of the M2 protein.
Sabine Neirynck;Tom Deroo;Xavier Saelens;Peter Vanlandschoot.
Nature Medicine (1999)
The role of mitochondrial factors in apoptosis: a Russian roulette with more than one bullet.
G van Loo;X Saelens;M van Gurp;M MacFarlane.
Cell Death & Differentiation (2002)
Mitochondrial intermembrane proteins in cell death.
Maria van Gurp;Nele Festjens;Geert van Loo;Xavier Saelens.
Biochemical and Biophysical Research Communications (2003)
Alice in caspase land. A phylogenetic analysis of caspases from worm to man.
Mohamed Lamkanfi;Wim Declercq;Michaël Kalai;Xavier Saelens.
Cell Death & Differentiation (2002)
Universal Vaccine Based on Ectodomain of Matrix Protein 2 of Influenza A: Fc Receptors and Alveolar Macrophages Mediate Protection
Karim El Bakkouri;Francis Descamps;Marina De Filette;Anouk Smet.
Journal of Immunology (2011)
Universal M2 ectodomain-based influenza A vaccines: preclinical and clinical developments
Michael Schotsaert;Marina De Filette;Walter Fiers;Xavier Saelens.
Expert Review of Vaccines (2009)
Structural Basis for Potent Neutralization of Betacoronaviruses by Single-Domain Camelid Antibodies.
Daniel Wrapp;Dorien De Vlieger;Kizzmekia S. Corbett;Gretel M. Torres.
Cell (2020)
M2e-based universal influenza A vaccine.
Lei Deng;Ki Joon Cho;Walter Fiers;Xavier Saelens.
Vaccine (2009)
Correction: Corrigendum: Potent single-domain antibodies that arrest respiratory syncytial virus fusion protein in its prefusion state
Iebe Rossey;Morgan S. A. Gilman;Stephanie C. Kabeche;Koen Sedeyn.
Nature Communications (2017)
Vaccine
(Impact Factor: 4.169)
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