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Geert van Loo

Geert van Loo

D-Index & Metrics

Biology and Biochemistry

D-Index
72
Citations
25440
World Ranking
6160
National Ranking
103

Overview

Geert van Loo is affiliated with Ghent University in Belgium and focuses on research within the fields of Biochemistry, Genetics and Molecular Biology, Medicine, and Immunology and Microbiology. Their work spans multiple subfields including Immunology, Molecular Biology, Cancer Research, Epidemiology, and Oncology.

The scientist has authored numerous publications, frequently contributing to journals such as Nature, bioRxiv (Cold Spring Harbor Laboratory), Cell Death and Differentiation, Cell Death and Disease, and Frontiers in Immunology.

Their research addresses main topics including:

  • Inflammasome and immune disorders
  • NF-κB Signaling Pathways
  • Immune Response and Inflammation
  • Interferon and immune responses
  • Ubiquitin and proteasome pathways
  • Immune cells in cancer
  • Cancer Research and Treatments

Recent significant papers authored by Geert van Loo and colleagues include:

  • Death by TNF: a road to inflammation, 2022, Nature reviews. Immunology
  • Targeting SLC7A11 improves efferocytosis by dendritic cells and wound healing in diabetes, 2022, Nature
  • ADAR1 prevents autoinflammation by suppressing spontaneous ZBP1 activation, 2022, Nature
  • A20 and Cell Death-driven Inflammation, 2020, Trends in Immunology
  • Microbes exploit death-induced nutrient release by gut epithelial cells, 2021, Nature

They often collaborate with other researchers, with frequent co-authors including Esther Hoste, Lars Vereecke, Andy Wullaert, Mozes Sze, and Gillian Blancke.

Best Publications

  • Identification of Oxidative Stress and Toll-like Receptor 4 Signaling as a Key Pathway of Acute Lung Injury

    Yumiko Imai;Keiji Kuba;Keiji Kuba;G. Greg Neely;Rubina Yaghubian-Malhami

  • Toxic proteins released from mitochondria in cell death

    Xavier Saelens;Nele Festjens;Lieselotte Vande Walle;Maria van Gurp

  • Spatial and temporal heterogeneity of mouse and human microglia at single-cell resolution.

    Takahiro Masuda;Roman Sankowski;Ori Staszewski;Chotima Böttcher

  • Epithelial NEMO links innate immunity to chronic intestinal inflammation

    Arianna Nenci;Christoph Becker;Andy Wullaert;Ralph Gareus

  • Inhibition of Caspases Increases the Sensitivity of L929 Cells to Necrosis Mediated by Tumor Necrosis Factor

    Dominique Vercammen;Rudi Beyaert;Geertrui Denecker;Vera Goossens

  • Deletion of NEMO/IKKγ in Liver Parenchymal Cells Causes Steatohepatitis and Hepatocellular Carcinoma

    Tom Luedde;Tom Luedde;Naiara Beraza;Vasileios Kotsikoris;Geert van Loo

  • FADD prevents RIP3-mediated epithelial cell necrosis and chronic intestinal inflammation

    Patrick-Simon Welz;Andy Wullaert;Katerina Vlantis;Vangelis Kondylis

  • Inflammasomes in neuroinflammatory and neurodegenerative diseases.

    Sofie Voet;Sahana Srinivasan;Mohamed Lamkanfi;Mohamed Lamkanfi;Geert van Loo

  • Farm dust and endotoxin protect against allergy through A20 induction in lung epithelial cells

    Martijn J. Schuijs;Monique A. Willart;Karl Vergote;Delphine Gras

  • The ubiquitin-editing enzyme A20 (TNFAIP3) is a central regulator of immunopathology

    Lars Vereecke;Rudi Beyaert;Geert van Loo

  • Mitochondrial intermembrane proteins in cell death.

    Maria van Gurp;Nele Festjens;Geert van Loo;Xavier Saelens

  • Negative regulation of the NLRP3 inflammasome by A20 protects against arthritis

    Lieselotte Vande Walle;Nina Van Opdenbosch;Peggy Jacques;Amelie Fossoul

  • CCR2 recruits an inflammatory macrophage subpopulation critical for angiogenesis in tissue repair

    Sebastian Willenborg;Tina Lucas;Geert van Loo;Geert van Loo;Johanna A. Knipper

  • Attenuation of cGAS-STING Signaling Is Mediated by a p62/SQSTM1-dependent Autophagy Pathway Activated by TBK1

    Thaneas Prabakaran;Chiranjeevi Bodda;Chiranjeevi Bodda;Christian Krapp;Bao‐cun Zhang

  • A20 in inflammation and autoimmunity.

    Leen Catrysse;Lars Vereecke;Rudi Beyaert;Geert van Loo

  • Microglia in Central Nervous System Inflammation and Multiple Sclerosis Pathology.

    Sofie Voet;Sofie Voet;Marco Prinz;Geert van Loo;Geert van Loo

  • The adaptor protein FADD protects epidermal keratinocytes from necroptosis in vivo and prevents skin inflammation

    Marion C. Bonnet;Daniela Preukschat;Patrick-Simon Welz;Geert van Loo

  • RIPK1 ensures intestinal homeostasis by protecting the epithelium against apoptosis

    Nozomi Takahashi;Lars Vereecke;Mathieu J. M. Bertrand;Linde Duprez

  • Inflammation and the Metabolic Syndrome: The Tissue-Specific Functions of NF-κB.

    Leen Catrysse;Geert van Loo

  • Enterocyte-specific A20 deficiency sensitizes to tumor necrosis factor–induced toxicity and experimental colitis

    Lars Vereecke;Mozes Sze;Conor Mc Guire;Brecht Rogiers

Frequent Co-Authors

Rudi Beyaert
Rudi Beyaert Ghent University
Manolis Pasparakis
Manolis Pasparakis University of Cologne
Peter Vandenabeele
Peter Vandenabeele Ghent University
Bart N. Lambrecht
Bart N. Lambrecht Ghent University
Wim Declercq
Wim Declercq Ghent University
Marco Prinz
Marco Prinz University of Freiburg
Mirjam Kool
Mirjam Kool Erasmus University Rotterdam
Xavier Saelens
Xavier Saelens Ghent University
Marc Schmidt-Supprian
Marc Schmidt-Supprian Technical University of Munich
Mathieu J.M. Bertrand
Mathieu J.M. Bertrand Ghent University

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