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Marc Schmidt-Supprian

Marc Schmidt-Supprian

D-Index & Metrics

Biology and Biochemistry

D-Index
59
Citations
16184
World Ranking
12357
National Ranking
880

Overview

Marc Schmidt-Supprian is affiliated with the Technical University of Munich in Germany. Their research mainly spans across multiple intersecting fields, with a focus on biochemistry, genetics, molecular biology, medicine, and immunology and microbiology.

Their scholarly output reflects significant contributions in subfields such as immunology, molecular biology, oncology, cancer research, and genetics. Central topics addressed include immune cell function and interaction, T-cell and B-cell immunology, pancreatic and hepatic oncology research, cancer immunotherapy and biomarkers, immunotherapy and immune responses, NF-κB signaling pathways, and protein degradation and inhibitors.

Marc Schmidt-Supprian's recent published papers include:

  • "Context-Specific Determinants of the Immunosuppressive Tumor Microenvironment in Pancreatic Cancer," 2023, Cancer Discovery
  • "Selective multi-kinase inhibition sensitizes mesenchymal pancreatic cancer to immune checkpoint blockade by remodeling the tumor microenvironment," 2022, Nature Cancer
  • "Cathepsin S Alterations Induce a Tumor-Promoting Immune Microenvironment in Follicular Lymphoma," 2020, Cell Reports
  • "Neutrophil 'plucking' on megakaryocytes drives platelet production and boosts cardiovascular disease," 2022, Immunity
  • "B cells orchestrate tolerance to the neuromyelitis optica autoantigen AQP4," 2024, Nature

Their work has appeared frequently in publications such as bioRxiv (Cold Spring Harbor Laboratory), Immunity, Nature Communications, Cancer Research, and Cancer Discovery.

Frequent collaborators include Roland Rad, Dieter Saur, Rupert Öllinger, Günter Schneider, and Katja Steiger, with collaboration counts ranging from eight to fifteen joint works.

Best Publications

  • Regulation of the Germinal Center Response by MicroRNA-155

    To-Ha Thai;Dinis Pedro Calado;Stefano Casola;K. Mark Ansel

  • NEMO/IKKγ-Deficient Mice Model Incontinentia Pigmenti

    Marc Schmidt-Supprian;Wilhelm Bloch;Gilles Courtois;Klaus Addicks

  • Vagaries of conditional gene targeting

    Marc Schmidt-Supprian;Klaus Rajewsky

  • TNF-mediated inflammatory skin disease in mice with epidermis-specific deletion of IKK2

    Manolis Pasparakis;Gilles Courtois;Martin Hafner;Martin Hafner;Marc Schmidt-Supprian;Marc Schmidt-Supprian

  • Phosphatidylcholine Synthesis for Lipid Droplet Expansion Is Mediated by Localized Activation of CTP:Phosphocholine Cytidylyltransferase

    Natalie Krahmer;Yi Guo;Florian Wilfling;Maximiliane Hilger

  • Canonical NF-κB Activity, Dispensable for B Cell Development, Replaces BAFF-Receptor Signals and Promotes B Cell Proliferation upon Activation

    Yoshiteru Sasaki;Emmanuel Derudder;Elias Hobeika;Roberta Pelanda

  • Trans-presentation of IL-6 by dendritic cells is required for the priming of pathogenic T H 17 cells

    Sylvia Heink;Nir Yogev;Christoph Garbers;Marina Herwerth

  • K+ Efflux-Independent NLRP3 Inflammasome Activation by Small Molecules Targeting Mitochondria

    Christina J. Groß;Ritu Mishra;Katharina S. Schneider;Guillaume Médard

  • TNF family member B cell-activating factor (BAFF) receptor-dependent and -independent roles for BAFF in B cell physiology.

    Yoshiteru Sasaki;Stefano Casola;Jeffery L. Kutok;Klaus Rajewsky

  • γ-secretase directly sheds the survival receptor BCMA from plasma cells

    Sarah A. Laurent;Franziska S. Hoffmann;Peer-Hendrik Kuhn;Qingyu Cheng

  • Cleavage of roquin and regnase-1 by the paracaspase MALT1 releases their cooperatively repressed targets to promote T(H)17 differentiation

    Katharina M. Jeltsch;Desheng Hu;Sven Brenner;Jessica Zöller

  • Continuous T Cell Receptor Signals Maintain a Functional Regulatory T Cell Pool

    J. Christoph Vahl;Christoph Drees;Klaus Heger;Sylvia Heink

  • A bacterial E3 ubiquitin ligase IpaH9.8 targets NEMO/IKK|[gamma]| to dampen the host NF-|[kappa]|B-mediated inflammatory response

    Hiroshi Ashida;Minsoo Kim;Marc Schmidt-Supprian;Averil Ma

  • Tissue-specific tumorigenesis: context matters.

    Günter Schneider;Marc Schmidt-Supprian;Roland Rad;Dieter Saur

  • A20 (TNFAIP3) deficiency in myeloid cells triggers erosive polyarthritis resembling rheumatoid arthritis

    Mourad Matmati;Peggy Jacques;Jonathan Maelfait;Jonathan Maelfait;Eveline Verheugen

  • Enterocyte-specific A20 deficiency sensitizes to tumor necrosis factor–induced toxicity and experimental colitis

    Lars Vereecke;Mozes Sze;Conor Mc Guire;Brecht Rogiers

  • Yin Yang 1 is a critical regulator of B-cell development

    Huifei Liu;Marc Schmidt-Supprian;Yujiang Shi;Elias Hobeika

  • Differential dependence of CD4+CD25+ regulatory and natural killer-like T cells on signals leading to NF-κB activation

    Marc Schmidt-Supprian;Jane Tian;Ethan P. Grant;Manolis Pasparakis

  • Mature T cells depend on signaling through the IKK complex

    Marc Schmidt-Supprian;Gilles Courtois;Jane Tian;Anthony J. Coyle

  • Inhibition of transcription factor NF-kappaB in the central nervous system ameliorates autoimmune encephalomyelitis in mice.

    Geert van Loo;Rossana De Lorenzi;Hauke Schmidt;Marion Huth

Frequent Co-Authors

Klaus Rajewsky
Klaus Rajewsky Max Delbrück Center for Molecular Medicine
Manolis Pasparakis
Manolis Pasparakis University of Cologne
Geert van Loo
Geert van Loo Ghent University
Rudi Beyaert
Rudi Beyaert Ghent University
Christian Peschel
Christian Peschel Technical University of Munich
Jürgen Ruland
Jürgen Ruland Technical University of Munich
Daniel Krappmann
Daniel Krappmann Ludwig-Maximilians-Universität München
Jeffery L. Kutok
Jeffery L. Kutok Epizyme (United States)
Matthias Mann
Matthias Mann Max Planck Institute of Biochemistry
Roland Rad
Roland Rad Technical University of Munich

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