D-Index & Metrics Best Publications
Research.com 2022 Best Scientist Award Badge
Molecular Biology
USA
2023

D-Index & Metrics D-index (Discipline H-index) only includes papers and citation values for an examined discipline in contrast to General H-index which accounts for publications across all disciplines.

Discipline name D-index D-index (Discipline H-index) only includes papers and citation values for an examined discipline in contrast to General H-index which accounts for publications across all disciplines. Citations Publications World Ranking National Ranking
Best Scientists D-index 261 Citations 301,535 746 World Ranking 29 National Ranking 23
Molecular Biology D-index 258 Citations 279,703 666 World Ranking 1 National Ranking 1

Research.com Recognitions

Awards & Achievements

2023 - Research.com Molecular Biology in United States Leader Award

2022 - Research.com Best Scientist Award

2022 - Research.com Genetics and Molecular Biology in United States Leader Award

2011 - Member of the National Academy of Medicine (NAM)

2005 - Member of the National Academy of Sciences

Overview

What is he best known for?

The fields of study he is best known for:

  • Gene
  • Enzyme
  • Cancer

The scientist’s investigation covers issues in Cell biology, Transcription factor, Signal transduction, Immunology and Inflammation. His Cell biology study combines topics from a wide range of disciplines, such as Apoptosis, Programmed cell death and Regulation of gene expression. His studies deal with areas such as Proinflammatory cytokine, Molecular biology, Cell cycle and Immune system as well as Transcription factor.

His work deals with themes such as Oxidative stress, Kinase, Cell growth and Phosphorylation, which intersect with Signal transduction. His Immunology research includes elements of Carcinogenesis, Cancer and Cancer research. Michael Karin usually deals with Inflammation and limits it to topics linked to Endocrinology and Necrosis.

His most cited work include:

  • Immunity, Inflammation, and Cancer (5969 citations)
  • Mammalian MAP kinase signalling cascades (4278 citations)
  • Phosphorylation meets ubiquitination: the control of NF-[kappa]B activity. (4173 citations)

What are the main themes of his work throughout his whole career to date?

Michael Karin focuses on Cell biology, Cancer research, Immunology, Molecular biology and Signal transduction. His Cell biology research incorporates elements of Transcription factor and Biochemistry. His study in Transcription factor is interdisciplinary in nature, drawing from both Regulation of gene expression and Transcription.

Michael Karin interconnects Carcinogenesis, Cancer cell and Cell growth in the investigation of issues within Cancer research. His Molecular biology research includes themes of Gene expression, Gene, Transactivation and c-jun. His Kinase research incorporates themes from Endocrinology, Internal medicine and Phosphorylation.

He most often published in these fields:

  • Cell biology (34.85%)
  • Cancer research (25.50%)
  • Immunology (20.03%)

What were the highlights of his more recent work (between 2015-2021)?

  • Cancer research (25.50%)
  • Inflammation (17.36%)
  • Cell biology (34.85%)

In recent papers he was focusing on the following fields of study:

His scientific interests lie mostly in Cancer research, Inflammation, Cell biology, Cancer and Internal medicine. His Cancer research research is multidisciplinary, incorporating perspectives in Carcinogenesis, Cancer cell, Downregulation and upregulation and Cell growth. He studied Carcinogenesis and Kinase that intersect with Protein subunit, Phosphorylation and IκB kinase.

The various areas that Michael Karin examines in his Inflammation study include Ubiquitin and Immune system, Immunity. He studies Cell biology, focusing on Signal transduction in particular. His Internal medicine research includes themes of Endocrinology and Oncology.

Between 2015 and 2021, his most popular works were:

  • Molecular mechanisms of cell death: recommendations of the Nomenclature Committee on Cell Death 2018. (1421 citations)
  • NF-κB, inflammation, immunity and cancer: coming of age (622 citations)
  • NF-κB Restricts Inflammasome Activation via Elimination of Damaged Mitochondria (458 citations)

In his most recent research, the most cited papers focused on:

  • Gene
  • Enzyme
  • Cancer

His primary areas of study are Cell biology, Inflammation, Autophagy, Immunology and Cancer research. His research combines Immunity and Cell biology. His Inflammation research includes elements of Cytotoxic T cell, Immune system and Cancer immunotherapy.

His Autophagy study combines topics in areas such as Sarcopenia, mTORC1, Receptor, Regeneration and Programmed cell death. His work deals with themes such as Liver cancer and Cancer, which intersect with Immunology. The Cancer research study combines topics in areas such as Carcinogenesis, Progenitor cell, Mdm2, KRAS and Phosphorylation.

This overview was generated by a machine learning system which analysed the scientist’s body of work. If you have any feedback, you can contact us here.

Best Publications

Immunity, Inflammation, and Cancer

Sergei I. Grivennikov;Florian R. Greten;Michael Karin.
Cell (2010)

10136 Citations

Mammalian MAP kinase signalling cascades

Lufen Chang;Michael Karin.
Nature (2001)

6384 Citations

Phosphorylation meets ubiquitination: the control of NF-[kappa]B activity.

Michael Karin;Yinon Ben-Neriah.
Annual Review of Immunology (2000)

6152 Citations

Nuclear factor-kappaB in cancer development and progression.

Michael Karin.
Nature (2006)

5338 Citations

Missing Pieces in the NF-κB Puzzle

Sankar Ghosh;Michael Karin.
Cell (2002)

4812 Citations

The role of Jun, Fos and the AP-1 complex in cell-proliferation and transformation.

Peter Angel;Michael Karin.
Biochimica et Biophysica Acta (1991)

4662 Citations

JNK1: A protein kinase stimulated by UV light and Ha-Ras that binds and phosphorylates the c-Jun activation domain

Benoit Dérijard;Benoit Dérijard;Masahiko Hibi;I-Huan Wu;I-Huan Wu;Tamera Barrett.
Cell (1994)

4001 Citations

A central role for JNK in obesity and insulin resistance

Jiro Hirosumi;Gürol Tuncman;Lufen Chang;Cem Z. Görgün.
Nature (2002)

3894 Citations

Phorbol ester-inducible genes contain a common cis element recognized by a TPA-modulated trans-acting factor.

Peter Angel;Masayoshi Imagawa;Robert Chiu;Bernd Stein.
Cell (1987)

3631 Citations

NF-κB at the crossroads of life and death

Michael Karin;Anning Lin.
Nature Immunology (2002)

3488 Citations

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