H-Index & Metrics Top Publications

H-Index & Metrics

Discipline name H-index Citations Publications World Ranking National Ranking
Genetics and Molecular Biology H-index 204 Citations 192,223 410 World Ranking 10 National Ranking 6

Research.com Recognitions

Awards & Achievements

2011 - Member of the National Academy of Medicine (NAM)

2005 - Member of the National Academy of Sciences

Overview

What is he best known for?

The fields of study he is best known for:

  • Gene
  • Enzyme
  • Cancer

The scientist’s investigation covers issues in Cell biology, Transcription factor, Signal transduction, Immunology and Inflammation. His Cell biology study combines topics from a wide range of disciplines, such as Apoptosis, Programmed cell death and Regulation of gene expression. His studies deal with areas such as Proinflammatory cytokine, Molecular biology, Cell cycle and Immune system as well as Transcription factor.

His work deals with themes such as Oxidative stress, Kinase, Cell growth and Phosphorylation, which intersect with Signal transduction. His Immunology research includes elements of Carcinogenesis, Cancer and Cancer research. Michael Karin usually deals with Inflammation and limits it to topics linked to Endocrinology and Necrosis.

His most cited work include:

  • Immunity, Inflammation, and Cancer (5969 citations)
  • Mammalian MAP kinase signalling cascades (4278 citations)
  • Phosphorylation meets ubiquitination: the control of NF-[kappa]B activity. (4173 citations)

What are the main themes of his work throughout his whole career to date?

Michael Karin focuses on Cell biology, Cancer research, Immunology, Molecular biology and Signal transduction. His Cell biology research incorporates elements of Transcription factor and Biochemistry. His study in Transcription factor is interdisciplinary in nature, drawing from both Regulation of gene expression and Transcription.

Michael Karin interconnects Carcinogenesis, Cancer cell and Cell growth in the investigation of issues within Cancer research. His Molecular biology research includes themes of Gene expression, Gene, Transactivation and c-jun. His Kinase research incorporates themes from Endocrinology, Internal medicine and Phosphorylation.

He most often published in these fields:

  • Cell biology (34.85%)
  • Cancer research (25.50%)
  • Immunology (20.03%)

What were the highlights of his more recent work (between 2015-2021)?

  • Cancer research (25.50%)
  • Inflammation (17.36%)
  • Cell biology (34.85%)

In recent papers he was focusing on the following fields of study:

His scientific interests lie mostly in Cancer research, Inflammation, Cell biology, Cancer and Internal medicine. His Cancer research research is multidisciplinary, incorporating perspectives in Carcinogenesis, Cancer cell, Downregulation and upregulation and Cell growth. He studied Carcinogenesis and Kinase that intersect with Protein subunit, Phosphorylation and IκB kinase.

The various areas that Michael Karin examines in his Inflammation study include Ubiquitin and Immune system, Immunity. He studies Cell biology, focusing on Signal transduction in particular. His Internal medicine research includes themes of Endocrinology and Oncology.

Between 2015 and 2021, his most popular works were:

  • Molecular mechanisms of cell death: recommendations of the Nomenclature Committee on Cell Death 2018. (1421 citations)
  • NF-κB, inflammation, immunity and cancer: coming of age (622 citations)
  • NF-κB Restricts Inflammasome Activation via Elimination of Damaged Mitochondria (458 citations)

In his most recent research, the most cited papers focused on:

  • Gene
  • Enzyme
  • Cancer

His primary areas of study are Cell biology, Inflammation, Autophagy, Immunology and Cancer research. His research combines Immunity and Cell biology. His Inflammation research includes elements of Cytotoxic T cell, Immune system and Cancer immunotherapy.

His Autophagy study combines topics in areas such as Sarcopenia, mTORC1, Receptor, Regeneration and Programmed cell death. His work deals with themes such as Liver cancer and Cancer, which intersect with Immunology. The Cancer research study combines topics in areas such as Carcinogenesis, Progenitor cell, Mdm2, KRAS and Phosphorylation.

This overview was generated by a machine learning system which analysed the scientist’s body of work. If you have any feedback, you can contact us here.

Top Publications

Immunity, Inflammation, and Cancer

Sergei I. Grivennikov;Florian R. Greten;Michael Karin.
Cell (2010)

8798 Citations

Mammalian MAP kinase signalling cascades

Lufen Chang;Michael Karin.
Nature (2001)

6149 Citations

Phosphorylation meets ubiquitination: the control of NF-[kappa]B activity.

Michael Karin;Yinon Ben-Neriah.
Annual Review of Immunology (2000)

5922 Citations

Missing pieces in the NF-kappaB puzzle.

Sankar Ghosh;Michael Karin.
Cell (2002)

5555 Citations

The role of Jun, Fos and the AP-1 complex in cell-proliferation and transformation.

Peter Angel;Michael Karin.
Biochimica et Biophysica Acta (1991)

4542 Citations

Nuclear factor-κB in cancer development and progression

Michael Karin.
Nature (2006)

3981 Citations

JNK1: A protein kinase stimulated by UV light and Ha-Ras that binds and phosphorylates the c-Jun activation domain

Benoit Dérijard;Benoit Dérijard;Masahiko Hibi;I-Huan Wu;I-Huan Wu;Tamera Barrett.
Cell (1994)

3902 Citations

A central role for JNK in obesity and insulin resistance

Jiro Hirosumi;Gürol Tuncman;Lufen Chang;Cem Z. Görgün.
Nature (2002)

3690 Citations

Phorbol ester-inducible genes contain a common cis element recognized by a TPA-modulated trans-acting factor.

Peter Angel;Masayoshi Imagawa;Robert Chiu;Bernd Stein.
Cell (1987)

3520 Citations

NF-κB at the crossroads of life and death

Michael Karin;Anning Lin.
Nature Immunology (2002)

3379 Citations

Profile was last updated on December 6th, 2021.
Research.com Ranking is based on data retrieved from the Microsoft Academic Graph (MAG).
The ranking h-index is inferred from publications deemed to belong to the considered discipline.

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