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Joseph A. DiDonato

Joseph A. DiDonato

Cleveland Clinic
United States

D-Index & Metrics

Biology and Biochemistry

D-Index
70
Citations
40312
World Ranking
6837
National Ranking
3153

Joseph A. DiDonato publication distribution in Biology and Biochemistry in 2026

The chart shows the distribution of publications by all Research.com ranked scientists in the field of Biology and Biochemistry in 2026. The highlighted bar marks where Joseph A. DiDonato sits on this spectrum.

47–56 publications: 8 scientists 57–66 publications: 35 scientists 67–76 publications: 106 scientists 77–86 publications: 231 scientists 87–96 publications: 414 scientists 97–106 publications: 546 scientists 107–116 publications: 704 scientists 117–126 publications: 849 scientists 127–136 publications: 980 scientists 137–146 publications: 942 scientists 147–156 publications: 969 scientists 157–166 publications: 950 scientists 167–176 publications: 951 scientists 177–186 publications: 915 scientists 187–196 publications: 787 scientists 197–206 publications: 841 scientists 207–216 publications: 735 scientists 217–226 publications: 709 scientists 227–236 publications: 651 scientists 237–246 publications: 605 scientists 247–256 publications: 510 scientists 257–266 publications: 524 scientists 267–276 publications: 434 scientists 277–286 publications: 418 scientists 287–296 publications: 350 scientists 297–306 publications: 363 scientists 307–316 publications: 315 scientists 317–326 publications: 296 scientists 327–336 publications: 261 scientists 337–346 publications: 240 scientists 347–356 publications: 219 scientists 357–366 publications: 197 scientists 367–376 publications: 154 scientists 377–386 publications: 161 scientists 387–396 publications: 155 scientists 397–406 publications: 145 scientists 407–416 publications: 124 scientists 417–426 publications: 112 scientists 427–436 publications: 132 scientists 437–446 publications: 116 scientists 447–456 publications: 99 scientists 457–466 publications: 81 scientists 467–476 publications: 91 scientists 477–486 publications: 80 scientists 487–496 publications: 80 scientists 497–506 publications: 60 scientists 507–516 publications: 36 scientists 517–526 publications: 46 scientists 527–536 publications: 54 scientists 537–546 publications: 44 scientists 547–556 publications: 43 scientists 557–566 publications: 43 scientists 567–576 publications: 42 scientists 577–586 publications: 25 scientists 587–596 publications: 34 scientists 597–606 publications: 23 scientists 607–616 publications: 33 scientists 617–626 publications: 31 scientists 627–636 publications: 27 scientists 637–646 publications: 25 scientists 647–656 publications: 28 scientists 657–666 publications: 34 scientists 667–676 publications: 18 scientists 677–686 publications: 16 scientists 687–696 publications: 10 scientists 697–706 publications: 12 scientists 707–716 publications: 21 scientists 717–726 publications: 12 scientists 727–736 publications: 12 scientists 737–746 publications: 10 scientists 747–756 publications: 7 scientists 757–766 publications: 13 scientists 767–776 publications: 15 scientists 777–786 publications: 13 scientists 787–796 publications: 9 scientists 797–806 publications: 9 scientists 807–816 publications: 7 scientists 817–826 publications: 4 scientists 827–836 publications: 9 scientists 837–846 publications: 7 scientists 847–856 publications: 3 scientists 857–866 publications: 5 scientists 867–876 publications: 5 scientists 877–886 publications: 11 scientists 887–896 publications: 3 scientists 897–906 publications: 4 scientists 907–916 publications: 7 scientists 917–926 publications: 5 scientists 927–936 publications: 6 scientists 937–946 publications: 6 scientists 947–956 publications: 3 scientists 957–966 publications: 7 scientists 967–976 publications: 2 scientists 977–986 publications: 2 scientists 987–996 publications: 1 scientists 997–1,006 publications: 5 scientists 1,007–1,016 publications: 2 scientists 1,017–1,026 publications: 2 scientists 1,027 publications: 1 scientists 1,028+ publications: 100 scientists
47 publications 1,028+

This scientist: 143 publications — 23rd percentile

23% of scientists in this discipline score the same or lower.

The last bar groups every scientist with 1,028 publications or more.

Joseph A. DiDonato D-index placement in Biology and Biochemistry in 2026

The chart shows the D-index (discipline H-index) distribution of Biology and Biochemistry scientists ranked by Research.com in 2026. The highlighted bar marks where Joseph A. DiDonato sits on this spectrum.

40–41 D-Index: 80 scientists 42–43 D-Index: 183 scientists 44–45 D-Index: 317 scientists 46–47 D-Index: 504 scientists 48–49 D-Index: 718 scientists 50–51 D-Index: 900 scientists 52–53 D-Index: 1,026 scientists 54–55 D-Index: 1,150 scientists 56–57 D-Index: 1,236 scientists 58–59 D-Index: 1,253 scientists 60–61 D-Index: 1,163 scientists 62–63 D-Index: 1,131 scientists 64–65 D-Index: 1,032 scientists 66–67 D-Index: 897 scientists 68–69 D-Index: 814 scientists 70–71 D-Index: 715 scientists 72–73 D-Index: 709 scientists 74–75 D-Index: 596 scientists 76–77 D-Index: 512 scientists 78–79 D-Index: 473 scientists 80–81 D-Index: 412 scientists 82–83 D-Index: 373 scientists 84–85 D-Index: 358 scientists 86–87 D-Index: 285 scientists 88–89 D-Index: 273 scientists 90–91 D-Index: 227 scientists 92–93 D-Index: 208 scientists 94–95 D-Index: 193 scientists 96–97 D-Index: 153 scientists 98–99 D-Index: 157 scientists 100–101 D-Index: 148 scientists 102–103 D-Index: 120 scientists 104–105 D-Index: 113 scientists 106–107 D-Index: 100 scientists 108–109 D-Index: 86 scientists 110–111 D-Index: 67 scientists 112–113 D-Index: 72 scientists 114–115 D-Index: 73 scientists 116–117 D-Index: 64 scientists 118–119 D-Index: 53 scientists 120–121 D-Index: 60 scientists 122–123 D-Index: 54 scientists 124–125 D-Index: 43 scientists 126–127 D-Index: 38 scientists 128–129 D-Index: 49 scientists 130–131 D-Index: 26 scientists 132–133 D-Index: 18 scientists 134–135 D-Index: 23 scientists 136–137 D-Index: 32 scientists 138–139 D-Index: 32 scientists 140–141 D-Index: 27 scientists 142–143 D-Index: 19 scientists 144–145 D-Index: 22 scientists 146–147 D-Index: 12 scientists 148–149 D-Index: 16 scientists 150–151 D-Index: 14 scientists 152–153 D-Index: 10 scientists 154–155 D-Index: 13 scientists 156–157 D-Index: 10 scientists 158–159 D-Index: 7 scientists 160–161 D-Index: 9 scientists 162–163 D-Index: 13 scientists 164–165 D-Index: 4 scientists 166 D-Index: 4 scientists 167+ D-Index: 98 scientists
40 D-Index 167+

This scientist: 70 D-Index — 65th percentile

65% of scientists in this discipline score the same or lower.

The last bar groups every scientist with 167 D-Index or more.

Overview

Joseph A. DiDonato is affiliated with the Cleveland Clinic in the United States. Their research spans several fields including Biochemistry, Genetics and Molecular Biology, and Medicine, with a particular focus on molecular biology and physiology. Their work sits at the intersection of clinical biochemistry, public health, and rheumatology.

The scientist's main topics of investigation involve gut microbiota and health, diet and metabolism studies, metabolomics and mass spectrometry studies, as well as nutritional studies and diet. Additional areas of interest include metabolism and genetic disorders, folate and B vitamins research, and connections between tryptophan and brain disorders.

Joseph A. DiDonato has contributed to multiple publications in notable scientific venues. These include:

  • Nature Medicine
  • Journal of Biological Chemistry
  • Circulation
  • Arteriosclerosis Thrombosis and Vascular Biology
  • Cell Host & Microbe

Recent papers authored or coauthored by the scientist highlight their investigation into the link between gut microbial metabolites and cardiovascular disease, chronic kidney disease, and heart failure. Selected recent publications include:

  • "A Cardiovascular Disease-Linked Gut Microbial Metabolite Acts via Adrenergic Receptors" (2020, Cell)
  • "Targeted Inhibition of Gut Microbial Trimethylamine N-Oxide Production Reduces Renal Tubulointerstitial Fibrosis and Functional Impairment in a Murine Model of Chronic Kidney Disease" (2020, Arteriosclerosis Thrombosis and Vascular Biology)
  • "Long-Term Changes in Gut Microbial Metabolite Trimethylamine N-Oxide and Coronary Heart Disease Risk" (2020, Journal of the American College of Cardiology)
  • "Gut microbes impact stroke severity via the trimethylamine N-oxide pathway" (2021, Cell Host & Microbe)
  • "Gut Microbiota-Generated Phenylacetylglutamine and Heart Failure" (2022, Circulation Heart Failure)

The scientist frequently collaborates with other researchers in their field, with notable co-authors including Stanley L. Hazen, Zeneng Wang, W.H. Wilson Tang, Xinmin S. Li, and Jennifer A. Buffa. Collaboration patterns show a consistent partnership with experts who contribute extensively to research on gut microbiota and cardiovascular health.

Best Publications

  • Gut flora metabolism of phosphatidylcholine promotes cardiovascular disease

    Zeneng Wang;Elizabeth Klipfell;Brian J. Bennett;Robert A. Koeth

  • Intestinal microbiota metabolism of L-carnitine, a nutrient in red meat, promotes atherosclerosis

    Robert A Koeth;Zeneng Wang;Bruce S Levison;Jennifer A Buffa

  • Immunosuppression by Glucocorticoids: Inhibition of NF-κB Activity Through Induction of IκB Synthesis

    Nathalie Auphan;Joseph A. DiDonato;Caridad Rosette;Arno Helmberg

  • A cytokine-responsive IκB kinase that activates the transcription factor NF-κB

    Joseph A. DiDonato;Makio Hayakawa;David M. Rothwarf;Ebrahim Zandi

  • Gut Microbial Metabolite TMAO Enhances Platelet Hyperreactivity and Thrombosis Risk.

    Weifei Zhu;Jill C. Gregory;Elin Org;Jennifer A. Buffa

  • NF-κB and the link between inflammation and cancer.

    Joseph A. DiDonato;Frank Mercurio;Michael Karin

  • Non-lethal Inhibition of Gut Microbial Trimethylamine Production for the Treatment of Atherosclerosis

    Zeneng Wang;Adam B. Roberts;Jennifer A. Buffa;Bruce S. Levison

  • Mapping of the inducible IkappaB phosphorylation sites that signal its ubiquitination and degradation.

    Joseph DiDonato;Frank Mercurio;Caridad Rosette;Jian Wu-Li

  • An agonist of toll-like receptor 5 has radioprotective activity in mouse and primate models.

    Lyudmila G. Burdelya;Vadim I. Krivokrysenko;Thomas C. Tallant;Evguenia Strom

  • NF-kappa B activation by ultraviolet light not dependent on a nuclear signal

    Yoram Devary;Caridad Rosette;Joseph A. DiDonato;Michael Karin

  • Protein carbamylation links inflammation, smoking, uremia and atherogenesis

    Zeneng Wang;Stephen J Nicholls;E Rene Rodriguez;Outi Kummu

  • A Cardiovascular Disease-Linked Gut Microbial Metabolite Acts via Adrenergic Receptors.

    Ina Nemet;Ina Nemet;Prasenjit Prasad Saha;Prasenjit Prasad Saha;Nilaksh Gupta;Nilaksh Gupta;Weifei Zhu;Weifei Zhu

  • γ-Butyrobetaine Is A Proatherogenic Intermediate in Gut Microbial Metabolism of L-Carnitine to TMAO

    Robert A. Koeth;Bruce S. Levison;Miranda K. Culley;Jennifer A. Buffa

  • Transmission of atherosclerosis susceptibility with gut microbial transplantation.

    Jill C. Gregory;Jennifer A. Buffa;Elin Org;Zeneng Wang

  • Phosphorylation of I kappa B alpha precedes but is not sufficient for its dissociation from NF-kappa B.

    Joseph A DiDonato;F. Mercurio;M. Karin

  • Development of a gut microbe-targeted nonlethal therapeutic to inhibit thrombosis potential

    Adam B Roberts;Adam B Roberts;Xiaodong Gu;Xiaodong Gu;Jennifer A Buffa;Jennifer A Buffa;Alex G Hurd;Alex G Hurd;Alex G Hurd

  • NF-κB activation by double-stranded-RNA-activated protein kinase (PKR) is mediated through NF-κB-inducing kinase and IκB kinase

    Maryam Zamanian-Daryoush;Trine H. Mogensen;Joseph A. DiDonato;Bryan R. G. Williams

  • NF-κB Is a Central Regulator of the Intestinal Epithelial Cell Innate Immune Response Induced by Infection with Enteroinvasive Bacteria

    Dirk Elewaut;Joseph A. DiDonato;Jung Mogg Kim;Jung Mogg Kim;Francis Truong

  • Activation of NF-κB is required for hypertrophic growth of primary rat neonatal ventricular cardiomyocytes

    Nicole H. Purcell;Guilin Tang;Chenfei Yu;Chenfei Yu;Frank Mercurio

  • An abundant dysfunctional apolipoprotein A1 in human atheroma

    Ying Huang;Joseph A DiDonato;Bruce S Levison;Dave Schmitt

Frequent Co-Authors

Stanley L. Hazen
Stanley L. Hazen Cleveland Clinic Lerner College of Medicine
W.H. Wilson Tang
W.H. Wilson Tang Cleveland Clinic
Jonathan D. Smith
Jonathan D. Smith Cleveland Clinic
Michael Karin
Michael Karin University of California, San Diego
Edward A. Fisher
Edward A. Fisher New York University
Aldons J. Lusis
Aldons J. Lusis University of California, Los Angeles
Paul L. Fox
Paul L. Fox Cleveland Clinic Lerner College of Medicine
Lu Qi
Lu Qi Harvard University
Keith M. Channon
Keith M. Channon University of Oxford
J. Mark Brown
J. Mark Brown Cleveland Clinic

External Links

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Related Online Degrees & Career Pathways

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With growing demand in healthcare fields, these online study options offer valuable, flexible career pathways aligned with a foundation in Biology and Biochemistry.

Best Scientists Citing Joseph A. DiDonato

Stanley L. Hazen

Stanley L. Hazen

Cleveland Clinic Lerner College of Medicine

Publications: 125

Michael Karin

Michael Karin

University of California, San Diego

Publications: 107

W.H. Wilson Tang

W.H. Wilson Tang

Cleveland Clinic

Publications: 84

Fredrik Bäckhed

Fredrik Bäckhed

University of Gothenburg

Publications: 65

Frank B. Hu

Frank B. Hu

Harvard University

Publications: 50

Albert S. Baldwin

Albert S. Baldwin

University of North Carolina at Chapel Hill

Publications: 42

Aldons J. Lusis

Aldons J. Lusis

University of California, Los Angeles

Publications: 39

Michael J. Davies

Michael J. Davies

University of Copenhagen

Publications: 37

Andrei V. Gudkov

Andrei V. Gudkov

Roswell Park Cancer Institute

Publications: 37

Rob Knight

Rob Knight

University of California, San Diego

Publications: 36

Christian Jobin

Christian Jobin

University of Florida

Publications: 34

Sankar Ghosh

Sankar Ghosh

Columbia University

Publications: 33

John Hiscott

John Hiscott

Istituto Pasteur

Publications: 33

Clare L. Hawkins

Clare L. Hawkins

University of Copenhagen

Publications: 32

Max Nieuwdorp

Max Nieuwdorp

University of Amsterdam

Publications: 32

Elaine Holmes

Elaine Holmes

Imperial College London

Publications: 32

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