World's Best Scientists 2026 revealed!
Mathias Heikenwalder

Mathias Heikenwalder

D-Index & Metrics

Immunology

D-Index
106
Citations
46514
World Ranking
559
National Ranking
31

Medicine

D-Index
106
Citations
46515
World Ranking
6466
National Ranking
367

Research.com Recognitions

  • 2019 - German National Academy of Sciences Leopoldina - Deutsche Akademie der Naturforscher Leopoldina – Nationale Akademie der Wissenschaften Human Genetics and Molecular Medicine

Overview

Mathias Heikenwalder is affiliated with the German Cancer Research Center in Germany. Their research primarily spans the fields of Medicine and Biochemistry, Genetics and Molecular Biology, with significant contributions to subfields including Molecular Biology, Immunology, Epidemiology, Oncology, and Hepatology.

The scientist's work has focused extensively on liver diseases and cancer, exploring topics such as:

  • Liver Disease Diagnosis and Treatment
  • Hepatitis C virus research
  • Hepatitis B Virus Studies
  • Hepatocellular Carcinoma Treatment and Prognosis
  • Cancer Immunotherapy and Biomarkers
  • Immune cells in cancer
  • Immune Cell Function and Interaction

Mathias Heikenwalder has published in several notable venues, often contributing to journals specializing in hepatology and cancer research. Frequent publication venues include:

  • Journal of Hepatology
  • Zeitschrift für Gastroenterologie
  • bioRxiv (Cold Spring Harbor Laboratory)
  • Nature Communications
  • Nature

Recent papers reflect a focus on liver cancer, inflammation, and immunological mechanisms, with titles and publication details such as:

  • Immunotherapies for hepatocellular carcinoma, 2021, Nature Reviews Clinical Oncology
  • The immunological and metabolic landscape in primary and metastatic liver cancer, 2021, Nature reviews. Cancer
  • Immune mechanisms linking metabolic injury to inflammation and fibrosis in fatty liver disease - novel insights into cellular communication circuits, 2022, Journal of Hepatology
  • Auto-aggressive CXCR6+ CD8 T cells cause liver immune pathology in NASH, 2021, Nature
  • SpaceM reveals metabolic states of single cells, 2021, Nature Methods

The scientist has collaborated frequently with other researchers, including:

  • Danijela Heide
  • Suchira Gallage
  • Tobias Riedl
  • Mohammad Rahbari
  • Thomas F. Baumert

Mathias Heikenwalder was recognized by election to the German National Academy of Sciences Leopoldina in 2019, specifically highlighting contributions in Human Genetics and Molecular Medicine.

Best Publications

  • Immunotherapies for hepatocellular carcinoma.

    Josep M Llovet;Josep M Llovet;Josep M Llovet;Florian Castet;Mathias Heikenwalder;Mala K Maini

  • Senescence surveillance of pre-malignant hepatocytes limits liver cancer development

    Tae-Won Kang;Tetyana Yevsa;Norman Woller;Lisa Hoenicke

  • Microglia emerge from erythromyeloid precursors via Pu.1- and Irf8-dependent pathways

    Katrin Kierdorf;Daniel Erny;Tobias Goldmann;Victor Sander

  • From NASH to HCC: current concepts and future challenges.

    Quentin M Anstee;Quentin M Anstee;Helen L Reeves;Helen L Reeves;Elena Kotsiliti;Olivier Govaere

  • The maternal microbiota drives early postnatal innate immune development

    Mercedes Gomez de Agüero;Stephanie C. Ganal-Vonarburg;Tobias Fuhrer;Sandra Rupp

  • Microglia in the adult brain arise from Ly-6ChiCCR2+ monocytes only under defined host conditions

    Alexander Mildner;Hauke Schmidt;Mirko Nitsche;Doron Merkler

  • NASH limits anti-tumour surveillance in immunotherapy-treated HCC

    Dominik Pfister;Dominik Pfister;Nicolás Gonzalo Núñez;Roser Pinyol;Olivier Govaere

  • Specific and nonhepatotoxic degradation of nuclear hepatitis B virus cccDNA.

    Julie Lucifora;Yuchen Xia;Florian Reisinger;Ke Zhang

  • The immunology of hepatocellular carcinoma.

    Marc Ringelhan;Dominik Pfister;Tracy O'Connor;Eli Pikarsky

  • Reversible Microbial Colonization of Germ-Free Mice Reveals the Dynamics of IgA Immune Responses

    Siegfried Hapfelmeier;Melissa A.E. Lawson;Emma Wetter Slack;Jorum K. Kirundi

  • mTOR regulates MAPKAPK2 translation to control the senescence-associated secretory phenotype

    Nicolás Herranz;Suchira Gallage;Massimiliano Mellone;Torsten Wuestefeld

  • NAFLD causes selective CD4 + T lymphocyte loss and promotes hepatocarcinogenesis

    Chi Ma;Aparna H. Kesarwala;Tobias Eggert;José Medina-Echeverz

  • A new type of microglia gene targeting shows TAK1 to be pivotal in CNS autoimmune inflammation

    Tobias Goldmann;Peter Wieghofer;Philippe F Müller;Yochai Wolf

  • Metabolic activation of intrahepatic CD8+ T cells and NKT cells causes nonalcoholic steatohepatitis and liver cancer via cross-talk with hepatocytes

    Monika Julia Wolf;Arlind Adili;Kira Piotrowitz;Zeinab Abdullah

  • Peripherally Applied Aβ-Containing Inoculates Induce Cerebral β-Amyloidosis

    Yvonne S. Eisele;Ulrike Obermüller;Ulrike Obermüller;Götz Heilbronner;Götz Heilbronner;Frank Baumann;Frank Baumann

  • Distinct Functions of Senescence-Associated Immune Responses in Liver Tumor Surveillance and Tumor Progression

    Tobias Eggert;Katharina Wolter;Juling Ji;Chi Ma

  • The immunological and metabolic landscape in primary and metastatic liver cancer

    Xin Li;Pierluigi Ramadori;Dominik Pfister;Marco Seehawer

  • Lymphoid follicle destruction and immunosuppression after repeated CpG oligodeoxynucleotide administration

    Mathias Heikenwalder;Magdalini Polymenidou;Tobias Junt;Christina Sigurdson

  • The Salmonella Pathogenicity Island (SPI)-2 and SPI-1 Type III Secretion Systems Allow Salmonella Serovar typhimurium to Trigger Colitis via MyD88-Dependent and MyD88-Independent Mechanisms

    Siegfried Hapfelmeier;Bärbel Stecher;Manja Barthel;Marcus Kremer

  • Interaction between tumour-infiltrating B cells and T cells controls the progression of hepatocellular carcinoma

    Marta Garnelo;Alex Tan;Zhisheng Her;Joe Yeong;Joe Yeong

  • A Lymphotoxin-Driven Pathway to Hepatocellular Carcinoma

    Johannes Haybaeck;Nicolas Zeller;Monika Julia Wolf;Achim Weber

Frequent Co-Authors

Achim Weber
Achim Weber University of Zurich
Ulrike Protzer
Ulrike Protzer Technical University of Munich
Percy A. Knolle
Percy A. Knolle Technical University of Munich
Adriano Aguzzi
Adriano Aguzzi University of Zurich
Marco Prinz
Marco Prinz University of Freiburg
Lars Zender
Lars Zender German Cancer Research Center
Roland Rad
Roland Rad Technical University of Munich
Christian Trautwein
Christian Trautwein RWTH Aachen University
Josep M. Llovet
Josep M. Llovet University of Barcelona
Petra Schwarz
Petra Schwarz University of Zurich

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