Virology, Follicular dendritic cells, Scrapie, Immunology and Cell biology are his primary areas of study. The various areas that he examines in his Follicular dendritic cells study include Spleen, Stromal cell, Immune complex and PRNP. His research in Scrapie intersects with topics in Molecular biology, Bovine spongiform encephalopathy, Germinal center and Pathogenesis.
His study on Immunology is mostly dedicated to connecting different topics, such as Disease. His Cell biology research is multidisciplinary, incorporating perspectives in Macrophage colony-stimulating factor, Paneth cell and Microfold cell. His studies examine the connections between Immune system and genetics, as well as such issues in Bone marrow, with regards to Immunohistochemistry and Severe combined immunodeficiency.
Neil A. Mabbott mostly deals with Immunology, Follicular dendritic cells, Immune system, Cell biology and Virology. Neil A. Mabbott has included themes like Transmissible spongiform encephalopathy and Disease in his Immunology study. His work deals with themes such as Scrapie, Stromal cell, Pathology, Germinal center and Spleen, which intersect with Follicular dendritic cells.
His research in the fields of Immunosenescence overlaps with other disciplines such as Population. His study in Cell biology is interdisciplinary in nature, drawing from both Microglia, Small intestine, Cellular differentiation and Microfold cell. The concepts of his Virology study are interwoven with issues in Trypanosoma brucei, Prion protein and In vivo.
His main research concerns Immunology, Immune system, Cell biology, Antigen and Disease. Immunology is closely attributed to Trypanosoma brucei in his research. Neil A. Mabbott studies Immune system, focusing on Follicular dendritic cells in particular.
His Follicular dendritic cells research is multidisciplinary, incorporating elements of Acquired immune system, Monoclonal antibody and Virology. His Cell biology research includes elements of Embryonic stem cell, Cellular differentiation, Microglia, Astrocyte and Glial fibrillary acidic protein. His study in the field of Microfold cell is also linked to topics like Chemistry.
Neil A. Mabbott mainly focuses on Antigen, Cell biology, Immune system, Immunology and T cell. His work carried out in the field of Cell biology brings together such families of science as Cellular differentiation, Downregulation and upregulation, Neurodegeneration, Glial fibrillary acidic protein and Transmissible spongiform encephalopathy. His Microfold cell study in the realm of Immune system interacts with subjects such as Chemistry.
His Microfold cell research incorporates elements of Humoral immunity, Antibody, Molecular biology, Ageing and Peyer's patch. His Immunology research includes themes of Small intestine and Stimulation. Neil A. Mabbott has researched T cell in several fields, including Immunoglobulin A, Tissue homeostasis and B cell, Immunoglobulin class switching.
This overview was generated by a machine learning system which analysed the scientist’s body of work. If you have any feedback, you can contact us here.
Microfold (M) cells: important immunosurveillance posts in the intestinal epithelium
Neil A. Mabbott;David S. Donaldson;Hiroshi Ohno;Ifor R. Williams.
Mucosal Immunology (2013)
Scrapie replication in lymphoid tissues depends on prion protein-expressing follicular dendritic cells.
K.L. Brown;K. Stewart;D.L. Ritchie;N.A. Mabbott.
Nature Medicine (1999)
Temporary inactivation of follicular dendritic cells delays neuroinvasion of scrapie.
Neil A. Mabbott;Fabienne Mackay;Fiona Minns;Moira E. Bruce.
Nature Medicine (2000)
Temporary depletion of complement component C3 or genetic deficiency of C1q significantly delays onset of scrapie
Neil A. Mabbott;Moira E. Bruce;Marina Botto;Mark J. Walport.
Nature Medicine (2001)
Prions and their lethal journey to the brain.
Neil A. Mabbott;G. Gordon MacPherson.
Nature Reviews Microbiology (2006)
Migrating intestinal dendritic cells transport PrPSc from the gut
Fangping Huang;Christine F. Farquhar;Neil A. Mabbott;Moira E. Bruce.
Journal of General Virology (2002)
An expression atlas of human primary cells: inference of gene function from coexpression networks
Neil A Mabbott;J Kenneth Baillie;Helen Brown;Tom C Freeman.
BMC Genomics (2013)
Follicular Dendritic Cell Dedifferentiation by Treatment with an Inhibitor of the Lymphotoxin Pathway Dramatically Reduces Scrapie Susceptibility
Neil A. Mabbott;Janice Young;Irene McConnell;Moira E. Bruce.
Journal of Virology (2003)
Salmonella Transforms Follicle-Associated Epithelial Cells into M Cells to Promote Intestinal Invasion
Amin Tahoun;Amin Tahoun;Simmi Mahajan;Edith Paxton;Georg Malterer.
Cell Host & Microbe (2012)
Tumor necrosis factor alpha-deficient, but not interleukin-6-deficient, mice resist peripheral infection with scrapie.
Neil A. Mabbott;Alun Williams;Christine F. Farquhar;Manolis Pasparakis.
Journal of Virology (2000)
If you think any of the details on this page are incorrect, let us know.
We appreciate your kind effort to assist us to improve this page, it would be helpful providing us with as much detail as possible in the text box below: