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Chemistry

D-Index
62
Citations
10030
World Ranking
9072
National Ranking
510

Biology and Biochemistry

D-Index
68
Citations
14891
World Ranking
7881
National Ranking
606

Overview

Edith Sim is affiliated with the University of Oxford in the United Kingdom. Their research spans multiple disciplines, with a primary focus on Medicine as well as Biochemistry, Genetics and Molecular Biology.

Their work touches upon several specific subfields, including Molecular Biology, Physiology, Materials Chemistry, Radiology, Nuclear Medicine and Imaging, and Endocrinology, Diabetes and Metabolism.

Edith Sim's research covers a variety of topics, such as:

  • Peroxisome Proliferator-Activated Receptors
  • Diet and metabolism studies
  • Nanoplatforms for cancer theranostics
  • Luminescence and Fluorescent Materials
  • Microbial Metabolic Engineering and Bioproduction
  • Microbial bioremediation and biosurfactants
  • Fungal and yeast genetics research

The scientist has published papers in diverse journals. Frequent publication venues include:

  • European Journal of Cancer
  • ChemBioChem
  • FEBS Journal
  • Immunobiology
  • Cellular and Molecular Life Sciences

Recent papers by Edith Sim are as follows:

  • Fusarium verticillioidesNAT1 (FDB2) N-malonyltransferase is structurally, functionally and phylogenetically distinct from its N-acetyltransferase (NAT) homologues, 2022, published in FEBS Journal
  • Intrinsic chemical reactivity of activated human complement component C3: A historical glimpse into research during 1979-1980 on the covalent binding properties of C3, C4 and alpha-2 macroglobulin, 2022, published in Immunobiology
  • Class I PI3Ks activate stretch-induced autophagy in trabecular meshwork cells, 2025, published in Cellular and Molecular Life Sciences
  • Predictors of upstage for invasive breast cancer in women with ductal carcinoma in-situ, 2024, published in European Journal of Cancer
  • Predictive value of contrast enhanced spectral mammography (CESM) and mammotome guided biopsy of clipped tumour in determining pathological complete response following neoadjuvant chemotherapy in breast cancer patients, 2024, published in European Journal of Cancer

Frequent collaborators in Edith Sim's research include:

  • Giannoulis Fakis
  • Robert B. Sim
  • Sotiria Boukouvala
  • Ern Yu Tan
  • Melody Cai-Syaun Wu

Best Publications

  • Metabolic gene polymorphism frequencies in control populations.

    S. Garte;L. Gaspari;A.K. Alexandrie;C. Ambrosone

  • A gene cluster encoding cholesterol catabolism in a soil actinomycete provides insight into Mycobacterium tuberculosis survival in macrophages

    Robert Van der Geize;Katherine Yam;Thomas Heuser;Maarten H. Wilbrink

  • Complement activation and protein adsorption by carbon nanotubes.

    Carolina Salvador-Morales;Emmanuel Flahaut;Edith Sim;Jeremy Sloan

  • Nomenclature for N-acetyltransferases.

    K P Vatsis;W W Weber;D A Bell;J M Dupret

  • Metabolic polymorphisms and cancer susceptibility.

    G Smith;L A Stanley;E Sim;R C Strange

  • The covalent-binding reaction of complement component C3.

    R B Sim;T M Twose;D S Paterson;E Sim

  • Slow N-acetylation genotype is a susceptibility factor in occupational and smoking related bladder cancer.

    Angela Risch;D M Wallace;S Bathers;E Sim

  • Influence of the apolipoprotein E genotype on amyloid deposition and neurofibrillary tangle formation in Alzheimer's disease

    Z.S. Nagy;M.M. Esiri;K.A. Jobst;C. Johnston

  • Structure of arylamine N-acetyltransferase reveals a catalytic triad

    John C. Sinclair;James Sandy;Rupika Delgoda;Edith Sim

  • Pharmacogenetics of the arylamine N-acetyltransferases.

    N J Butcher;S Boukouvala;E Sim;R F Minchin;R F Minchin

  • N-acetyltransferase polymorphism. Comparison of phenotype and genotype in humans.

    Dean Hickman;Edith Sim

  • Phenotyping of human complement component C4, a class-III HLA antigen.

    Edith Sim;Susan J. Cross

  • Expression of arylamine N-acetyltransferase in human intestine

    D Hickman;J Pope;S D Patil;G Fakis

  • Arylamine N-acetyltransferases: from drug metabolism and pharmacogenetics to drug discovery.

    E Sim;E Sim;A Abuhammad;A Abuhammad;A Ryan

  • Cloning and Characterization of Arylamine N -Acetyltransferase Genes from Mycobacterium smegmatis and Mycobacterium tuberculosis: Increased Expression …

    Unknown

  • Chromosomal localization of human genes for arylamine N-acetyltransferase

    D Hickman;Angela Risch;V Buckle;N K Spurr

  • Arylamine N-acetyltransferases: From Structure to Function

    Edith Sim;Kylie Walters;Sotiria Boukouvala

  • Current smoking, occupation, N-acetyltransferase-2 and bladder cancer: a pooled analysis of genotype-based studies.

    Paolo Vineis;Daniela Marinelli;Herman Autrup;Jurgen Brockmoller

  • Autolytic fragmentation of complement components C3 and C4 under denaturing conditions, a property shared with α 2-macroglobulin

    Unknown

  • Arylamine N-acetyltransferases: Structural and functional implications of polymorphisms

    Edith Sim;Nathan Lack;Chan-Ju Wang;Hilary Long

  • Purification of human C3b inactivator by monoclonal-antibody affinity chromatography

    Li-min Hsiung;A. Neil Barclay;Malcolm R. Brandon;Edith Sim

  • Update on consensus arylamine N-acetyltransferase gene nomenclature.

    David W Hein;Denis M. Grant;Edith Sim

Frequent Co-Authors

Martin E.M. Noble
Martin E.M. Noble Newcastle University
Stephen G. Davies
Stephen G. Davies University of Oxford
Angela Risch
Angela Risch University of Salzburg
Robert B. Sim
Robert B. Sim University of Oxford
Elspeth F. Garman
Elspeth F. Garman University of Oxford
David W. Hein
David W. Hein University of Louisville
Lindsay D. Eltis
Lindsay D. Eltis University of British Columbia
Rodney F. Minchin
Rodney F. Minchin University of Queensland
Gurdyal S. Besra
Gurdyal S. Besra University of Birmingham
Ann K. Daly
Ann K. Daly Newcastle University

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