His primary areas of investigation include Microbiology, Complement system, Neisseria meningitidis, Factor H and Neisseria gonorrhoeae. His studies in Microbiology integrate themes in fields like Meningococcal vaccine, Immune system, Classical complement pathway and Virology. The study incorporates disciplines such as Laminarin and Plasma protein binding in addition to Complement system.
His Neisseria meningitidis research is multidisciplinary, relying on both Neisseriaceae and Immunity. The concepts of his Factor H study are interwoven with issues in Epitope, Alternative complement pathway, Binding protein and Innate immune system. His Neisseria gonorrhoeae research includes elements of Toll-like receptor, Interleukin 8, Cytokine, TLR2 and Transfection.
His main research concerns Microbiology, Neisseria gonorrhoeae, Complement system, Neisseria meningitidis and Factor H. Sanjay Ram has included themes like Alternative complement pathway, Antibody, Classical complement pathway and Virology in his Microbiology study. In his study, Virulence is strongly linked to Sialic acid, which falls under the umbrella field of Neisseria gonorrhoeae.
His studies deal with areas such as Innate immune system, Plasma protein binding and Complement as well as Complement system. In his research, Molecular biology is intimately related to Binding protein, which falls under the overarching field of Neisseria meningitidis. Sanjay Ram works mostly in the field of Factor H, limiting it down to topics relating to Complement inhibitor and, in certain cases, Fusion protein and Complement control protein.
His primary scientific interests are in Complement system, Neisseria gonorrhoeae, Microbiology, Antibody and Monoclonal antibody. His specific area of interest is Complement system, where Sanjay Ram studies Alternative complement pathway. As a part of the same scientific study, Sanjay Ram usually deals with the Alternative complement pathway, concentrating on Classical complement pathway and frequently concerns with Neisseria meningitidis.
His research integrates issues of Epitope, In vitro and Immune system in his study of Neisseria gonorrhoeae. His Microbiology research incorporates themes from Factor H, Fusion protein and Virulence. His Antibody research includes themes of Phagocytosis and Recombinant DNA.
Sanjay Ram focuses on Complement system, Innate immune system, Antibody, Neisseria gonorrhoeae and Antigen. He does research in Complement system, focusing on Alternative complement pathway specifically. His study explores the link between Innate immune system and topics such as Complement that cross with problems in Complement activity, Computational biology and Classical complement pathway.
Sanjay Ram interconnects Epitope, Sialic acid, Immune receptor and Virology in the investigation of issues within Neisseria gonorrhoeae. His Antigen study incorporates themes from Titer, Heterologous and Recombinant DNA. The Neisseria meningitidis study which covers Factor H that intersects with Microbiology.
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A novel sialic acid binding site on factor H mediates serum resistance of sialylated Neisseria gonorrhoeae.
Sanjay Ram;Ajay K. Sharma;Scott D. Simpson;Sunita Gulati.
Journal of Experimental Medicine (1998)
The Meningococcal Vaccine Candidate GNA1870 Binds the Complement Regulatory Protein Factor H and Enhances Serum Resistance
Guillermo Madico;Jo Anne Welsch;Lisa A. Lewis;Anne McNaughton.
Journal of Immunology (2006)
Infections of People with Complement Deficiencies and Patients Who Have Undergone Splenectomy
Sanjay Ram;Lisa A. Lewis;Peter A. Rice.
Clinical Microbiology Reviews (2010)
The new multicomponent vaccine against meningococcal serogroup B, 4CMenB: immunological, functional and structural characterization of the antigens.
Davide Serruto;Matthew J. Bottomley;Sanjay Ram;Marzia M. Giuliani.
Binding of Complement Factor H to Loop 5 of Porin Protein 1A: A Molecular Mechanism of Serum Resistance of Nonsialylated Neisseria gonorrhoeae
Sanjay Ram;Daniel P. McQuillen;Sunita Gulati;Christopher Elkins.
Journal of Experimental Medicine (1998)
Binding of C4b-binding protein to porin: a molecular mechanism of serum resistance of Neisseria gonorrhoeae
Sanjay Ram;Meabh Cullinane;Anna M. Blom;Sunita Gulati.
Journal of Experimental Medicine (2001)
Neisseria meningitidis GNA2132, a heparin-binding protein that induces protective immunity in humans
Davide Serruto;Tiziana Spadafina;Laura Ciucchi;Lisa A. Lewis.
Proceedings of the National Academy of Sciences of the United States of America (2010)
The Meningococcal Vaccine Candidate Neisserial Surface Protein A (NspA) Binds to Factor H and Enhances Meningococcal Resistance to Complement
Lisa A. Lewis;Jutamas Ngampasutadol;Ruth Wallace;Jane E. A. Reid.
PLOS Pathogens (2010)
Binding of Complement Factor H (fH) to Neisseria meningitidis Is Specific for Human fH and Inhibits Complement Activation by Rat and Rabbit Sera
Dan M. Granoff;Jo Anne Welsch;Sanjay Ram.
Infection and Immunity (2009)
The role of porins in neisserial pathogenesis and immunity.
Paola Massari;Sanjay Ram;Heather Macleod;Lee M. Wetzler.
Trends in Microbiology (2003)
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