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Astrid Gräslund

Astrid Gräslund

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Biology and Biochemistry
Sweden
2023

D-Index & Metrics

Chemistry

D-Index
90
Citations
24219
World Ranking
2114
National Ranking
30

Biology and Biochemistry

D-Index
88
Citations
23724
World Ranking
2746
National Ranking
46

Research.com Recognitions

  • 2023 - Research.com Biology and Biochemistry in Sweden Leader Award

Overview

Astrid Gräslund is affiliated with Stockholm University in Sweden. Their research spans the fields of biochemistry, genetics, molecular biology, and medicine, with a focus on molecular biology, physiology, nutrition and dietetics, materials chemistry, and biomaterials. The main topics of their work include Alzheimer's disease research and treatments, protein structure and dynamics, trace elements in health, prion diseases and protein misfolding, supramolecular self-assembly in materials, RNA interference and gene delivery, and enzyme structure and function.

The scientist has contributed to numerous research publications. Notable recent papers include:

  • Designed Cell-Penetrating Peptide Inhibitors of Amyloid-beta Aggregation and Cytotoxicity, 2020, Cell Reports Physical Science
  • A Hairpin Motif in the Amyloid-β Peptide Is Important for Formation of Disease-Related Oligomers, 2023, Journal of the American Chemical Society
  • Amyloid-β oligomers are captured by the DNAJB6 chaperone: Direct detection of interactions that can prevent primary nucleation, 2020, Journal of Biological Chemistry
  • Metal ion coordination delays amyloid-β peptide self-assembly by forming an aggregation-inert complex, 2020, Journal of Biological Chemistry
  • Studies on citrullinated LL-37: detection in human airways, antibacterial effects and biophysical properties, 2020, Scientific Reports

Frequent co-authors of Astrid Gräslund include:

  • Sebastian K.T.S. Wärmländer
  • Jüri Jarvet
  • Elina Berntsson
  • Andreas Barth
  • Nicklas Österlund

Their work has been published repeatedly in venues such as:

  • bioRxiv (Cold Spring Harbor Laboratory)
  • Journal of Biological Chemistry
  • Scientific Reports
  • Research Square (Research Square)
  • Cell Reports Physical Science

Best Publications

  • Cell Penetrating Peptides

    Mattias Hällbrink;Margus Pooga;Madis Metsis;Priit Kogerman

  • Mechanisms of Cellular Uptake of Cell-Penetrating Peptides

    Fatemeh Madani;Staffan Lindberg;Ülo Langel;Shiroh Futaki

  • A library of IR bands of nucleic acids in solution.

    Martina Banyay;Munna Sarkar;Astrid Gräslund

  • Ionic Effects on the Stability and Conformation of Peptide Nucleic Acid Complexes

    Sebastian Tomac;Munna Sarkar;Tommi Ratilainen;Pernilla Wittung

  • Efficient Intracellular Delivery of Nucleic Acid Pharmaceuticals Using Cell-Penetrating Peptides

    Ikuhiko Nakase;Hidetaka Akita;Kentaro Kogure;Astrid Gräslund

  • Cytosolic antibody delivery by lipid-sensitive endosomolytic peptide

    Misao Akishiba;Toshihide Takeuchi;Yoshimasa Kawaguchi;Kentarou Sakamoto

  • High-resolution NMR studies of the zinc-binding site of the Alzheimer's amyloid β-peptide

    Jens Danielsson;Roberta Pierattelli;Lucia Banci;Astrid Gräslund

  • Structure and dynamics of a fluorescent DNA oligomer containing the EcoRI recognition sequence: fluorescence, molecular dynamics, and NMR studies.

    Nordlund Tm;Andersson S;Nilsson L;Rigler R

  • The iron center in ribonucleotide reductase from Escherichia coli.

    L. Petersson;A. Gräslund;A. Ehrenberg;B.M. Sjöberg

  • Mammalian p53R2 protein forms an active ribonucleotide reductase in vitro with the R1 protein, which is expressed both in resting cells in response to DNA damage and in proliferating cells.

    Olivier Guittet;Pelle Håkansson;Nina Voevodskaya;Susan Fridd

  • The tyrosine free radical in ribonucleotide reductase from Escherichia coli.

    B M Sjöberg;P Reichard;A Gräslund;A Ehrenberg

  • Interaction and structure induction of cell-penetrating peptides in the presence of phospholipid vesicles.

    Mazin Magzoub;Kalle Kilk;L.E.Göran Eriksson;Ülo Langel

  • Role of ribonucleotide reductase in inhibition of mammalian cell growth by potent iron chelators.

    S Nyholm;G J Mann;A G Johansson;R J Bergeron

  • Conformational states of the cell-penetrating peptide penetratin when interacting with phospholipid vesicles: effects of surface charge and peptide concentration.

    Mazin Magzoub;L.E.Göran Eriksson;Astrid Gräslund

  • Translational diffusion measured by PFG-NMR on full length and fragments of the Alzheimer Aβ(1–40) peptide. Determination of hydrodynamic radii of random coil peptides of varying length

    Jens Danielsson;Jüri Jarvet;Peter Damberg;Astrid Gräslund

  • Reduction and loss of the iron center in the reaction of the small subunit of mouse ribonucleotide reductase with hydroxyurea.

    Nyholm S;Thelander L;Gräslund A

  • Cell-penetrating peptides: Small from inception to application

    Mazin Magzoub;Astrid Gräslund

  • The Radical Site in Chlamydial Ribonucleotide Reductase Defines a New R2 Subclass

    Martin Högbom;Pål Stenmark;Nina Voevodskaya;Grant McClarty

  • Positioning of the Alzheimer Aβ(1–40) peptide in SDS micelles using NMR and paramagnetic probes

    Jüri Jarvet;Jens Danielsson;Peter Damberg;Marta Oleszczuk

  • Effects of in vivo conditions on amyloid aggregation.

    Michael C Owen;David Gnutt;Mimi Gao;Sebastian K T S Wärmländer

  • Activation of the Anaerobic Ribonucleotide Reductase fromEscherichia coli

    S. Ollagnier;S. Ollagnier;E. Mulliez;P.P. Schmidt;R. Eliasson

Frequent Co-Authors

Britt-Marie Sjöberg
Britt-Marie Sjöberg Stockholm University
Ülo Langel
Ülo Langel Stockholm University
Lars Thelander
Lars Thelander Umeå University
Jan Pieter Abrahams
Jan Pieter Abrahams Paul Scherrer Institute
Bengt Nordén
Bengt Nordén Chalmers University of Technology
Anne-Laure Barra
Anne-Laure Barra Centre national de la recherche scientifique, CNRS
Friedhelm Lendzian
Friedhelm Lendzian Technical University of Berlin
Wolfgang Lubitz
Wolfgang Lubitz Max Planck Society
Rudolf Rigler
Rudolf Rigler Karolinska Institute
Georgy Bakalkin
Georgy Bakalkin Uppsala University

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