Lars Thelander

Overview

Best Publications

• Reduction of ribonucleotides.

  Lars Thelander;Peter Reichard

  1674
  Citations

• Survival of DNA damage in yeast directly depends on increased dNTP levels allowed by relaxed feedback inhibition of ribonucleotide reductase.

  Andrei Chabes;Bilyana Georgieva;Vladimir Domkin;Xiaolan Zhao

  542
  Citations

• Iron and Free Radical in Ribonucleotide Reductase EXCHANGE OF IRON AND MÖSSBAUER SPECTROSCOPY OF THE PROTEIN B2 SUBUNIT OF THE ESCHERICHIA COLI ENZYME

  Curtis L. Atkin;Lars Thelander;Peter Reichard;George Lang

  511
  Citations

• Inactivation of ribonucleotide reductase by nitric oxide.

  Michel Lepoivre;Franck Fieschi;Jacques Coves;Lars Thelander

  458
  Citations

• ENZYMATIC SYNTHESIS OF DEOXYRIBONUCLEOTIDES.V. PURIFICATION AND PROPERTIES OF THIOREDOXIN REDUCTASE FROM ESCHERICHIA COLI B.

  Moore Ec;Moore Ec;Reichard P;Reichard P;Thelander L;Thelander L

  453
  Citations

• Regulation of Mammalian Ribonucleotide Reduction and dNTP Pools after DNA Damage and in Resting Cells

  Pelle Håkansson;Anders Hofer;Lars Thelander

  394
  Citations

• The ribonucleotide reductase inhibitor Sml1 is a new target of the Mec1/Rad53 kinase cascade during growth and in response to DNA damage

  Xiaolan Zhao;Xiaolan Zhao;Andrei Chabes;Vladimir Domkin;Lars Thelander

  356
  Citations

• Mammalian p53R2 protein forms an active ribonucleotide reductase in vitro with the R1 protein, which is expressed both in resting cells in response to DNA damage and in proliferating cells.

  Olivier Guittet;Pelle Håkansson;Nina Voevodskaya;Susan Fridd

  279
  Citations

• S-phase-specific expression of mammalian ribonucleotide reductase R1 and R2 subunit mRNAs.

  Stefan Björklund;Sven Skog;Bernard Tribukait;Lars Thelander

  255
  Citations

• Allosteric regulation of calf thymus ribonucleoside diphosphate reductase.

  Staffan Eriksson;Lars Thelander;Margareta Akerman

  251
  Citations

• Controlled protein degradation regulates ribonucleotide reductase activity in proliferating mammalian cells during the normal cell cycle and in response to DNA damage and replication blocks.

  Andrei Chabes;Lars Thelander

  238
  Citations

• Ribonucleotide reductase from calf thymus. Separation of the enzyme into two nonidentical subunits, proteins M1 and M2.

  L Thelander;S Eriksson;M Akerman

  232
  Citations

• Mouse ribonucleotide reductase R2 protein: A new target for anaphase-promoting complex-Cdh1-mediated proteolysis

  Anna Lena Chabes;Cathie M. Pfleger;Marc W. Kirschner;Lars Thelander

  231
  Citations

• Ribonucleotide reductase from calf thymus. Purification and properties

  Y Engström;S Eriksson;L Thelander;M Akerman

  227
  Citations

• Role of ribonucleotide reductase in inhibition of mammalian cell growth by potent iron chelators.

  S Nyholm;G J Mann;A G Johansson;R J Bergeron

  221
  Citations

• Reduction and loss of the iron center in the reaction of the small subunit of mouse ribonucleotide reductase with hydroxyurea.

  Nyholm S;Thelander L;Gräslund A

  197
  Citations

• Yeast Sml1, a Protein Inhibitor of Ribonucleotide Reductase *

  Andrei Chabes;Vladimir Domkin;Lars Thelander

  192
  Citations

• The three-dimensional structure of mammalian ribonucleotide reductase protein R2 reveals a more-accessible iron-radical site than Escherichia coli R2.

  Björn Kauppi;Bettina B. Nielsen;Bettina B. Nielsen;S. Ramaswamy;S. Ramaswamy;Ingrid Kjøller Larsen;Ingrid Kjøller Larsen

  178
  Citations

• Metabolic fate of oxidized guanine ribonucleotides in mammalian cells

  Hiroshi Hayakawa;Anders Hofer;Lars Thelander;Shigetaka Kitajima

  170
  Citations

• Magnetic interaction between the tyrosyl free radical and the antiferromagnetically coupled iron center in ribonucleotide reductase.

  Margareta Sahlin;Leif Petersson;Astrid Graeslund;Anders Ehrenberg

  165
  Citations