What is he best known for?
The fields of study he is best known for:
His primary scientific interests are in Ribonucleotide reductase, Biochemistry, Ribonucleotide, DNA damage and DNA repair.
The concepts of his Ribonucleotide reductase study are interwoven with issues in In vitro and Allosteric regulation.
In the subject of general Biochemistry, his work in Enzyme, Protein subunit and RNA is often linked to Guanylate kinase, thereby combining diverse domains of study.
His studies deal with areas such as Transcription, RNA polymerase II, Stereochemistry and Kinase as well as Ribonucleotide.
His DNA damage research includes elements of Molecular biology, 7-Dehydrocholesterol reductase, Cell cycle and DNA synthesis.
His DNA repair research is multidisciplinary, incorporating perspectives in Deoxyribonucleotides, Ubiquitin and DNA replication.
His most cited work include:
- Reduction of ribonucleotides. (994 citations)
- Survival of DNA damage in yeast directly depends on increased dNTP levels allowed by relaxed feedback inhibition of ribonucleotide reductase. (366 citations)
- Inactivation of ribonucleotide reductase by nitric oxide. (298 citations)
What are the main themes of his work throughout his whole career to date?
His scientific interests lie mostly in Ribonucleotide reductase, Biochemistry, Molecular biology, Protein subunit and Ribonucleotide.
His research in Ribonucleotide reductase intersects with topics in Stereochemistry, Allosteric regulation, Binding site and Escherichia coli.
Much of his study explores Biochemistry relationship to Cell culture.
Lars Thelander combines subjects such as 7-Dehydrocholesterol reductase, Reductase, Promoter, Peptide sequence and Transcription with his study of Molecular biology.
His Protein subunit research also works with subjects such as
- Gene expression together with Intron and Messenger RNA,
- Mutant together with Open reading frame.
His work deals with themes such as DNA damage, DNA, DNA repair and Ribonucleotide Reductase Subunit, which intersect with Ribonucleotide.
He most often published in these fields:
- Ribonucleotide reductase (76.29%)
- Biochemistry (55.67%)
- Molecular biology (39.18%)
What were the highlights of his more recent work (between 2005-2019)?
- Ribonucleotide reductase (76.29%)
- Biochemistry (55.67%)
- Protein subunit (25.77%)
In recent papers he was focusing on the following fields of study:
His primary areas of study are Ribonucleotide reductase, Biochemistry, Protein subunit, Ribonucleotide and Molecular biology.
His work carried out in the field of Ribonucleotide reductase brings together such families of science as Catalysis, Stereochemistry, DNA repair, Nucleotide salvage and DNA replication.
In his study, Mitochondrial DNA replication is inextricably linked to DNA damage, which falls within the broad field of DNA repair.
His work on Ribonucleotide reductase activity and Ribonucleotide Reductase Subunit as part of general Protein subunit research is frequently linked to Replication, thereby connecting diverse disciplines of science.
His Ribonucleotide research includes themes of C-terminus, Binding site and Peptide.
His study looks at the relationship between Molecular biology and fields such as Gene, as well as how they intersect with chemical problems.
Between 2005 and 2019, his most popular works were:
- Regulation of Mammalian Ribonucleotide Reduction and dNTP Pools after DNA Damage and in Resting Cells (239 citations)
- Ribonucleotide reduction is a cytosolic process in mammalian cells independently of DNA damage (88 citations)
- p53R2-dependent ribonucleotide reduction provides deoxyribonucleotides in quiescent human fibroblasts in the absence of induced DNA damage. (84 citations)
In his most recent research, the most cited papers focused on:
Lars Thelander mainly investigates Biochemistry, Ribonucleotide reductase, DNA repair, DNA damage and Ribonucleotide.
His study in Protein subunit and DNA replication is carried out as part of his studies in Biochemistry.
His Protein subunit research integrates issues from Schizosaccharomyces pombe and DNA, DNA synthesis.
DNA replication is frequently linked to Mitochondrion in his study.
Many of his studies on Ribonucleotide reductase apply to Mitochondrial DNA replication as well.
The study incorporates disciplines such as Molecular biology, Thymidine and Nucleotide salvage in addition to Mitochondrial DNA replication.
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