World's Best Scientists 2026 revealed!

D-Index & Metrics

Genetics

D-Index
82
Citations
33973
World Ranking
1457
National Ranking
686

Research.com Recognitions

  • 2015 - Member of the National Academy of Sciences
  • 2011 - Fellow of the American Academy of Arts and Sciences
  • 2008 - Fellow of the American Association for the Advancement of Science (AAAS)

Overview

Rodney Rothstein is affiliated with Columbia University in the United States and primarily works in the field of Biochemistry, Genetics, and Molecular Biology. Their research focuses extensively on Molecular Biology, with key interests in domains such as DNA Repair Mechanisms, CRISPR and Genetic Engineering, and Genomics and Chromatin Dynamics.

The scientist has contributed to several areas of study, including:

  • DNA Repair Mechanisms
  • CRISPR and Genetic Engineering
  • Genomics and Chromatin Dynamics
  • Epigenetics and DNA Methylation
  • RNA modifications and cancer
  • Polyomavirus and related diseases
  • Molecular Biology Techniques and Applications

Rothstein's work is represented across various publication venues with notable contributions to:

  • bioRxiv (Cold Spring Harbor Laboratory)
  • Molecular Cell
  • Nucleic Acids Research
  • Cells
  • Nature Communications

Among the recent papers authored or co-authored by Rothstein are:

  • "Repair of replication-dependent double-strand breaks differs between the leading and lagging strands," 2024, Molecular Cell
  • "Aberrant DNA repair reveals a vulnerability in histone H3.3-mutant brain tumors," 2024, Nucleic Acids Research
  • "Strand asymmetry in the repair of replication dependent double-strand breaks," 2024, bioRxiv (Cold Spring Harbor Laboratory)
  • "The Ultimate (Mis)match: When DNA Meets RNA," 2021, Cells
  • "DNA lesions can frequently precede DNA:RNA hybrid accumulation," 2025, Nature Communications

The scientist collaborates regularly with several researchers including Robert J. D. Reid, Lorraine S. Symington, Michael T. Kimble, Aakanksha Sane, and M. J. Johnson.

Rodney Rothstein has been recognized with several awards such as:

  • Member of the National Academy of Sciences, 2015
  • Fellow of the American Academy of Arts and Sciences, 2011
  • Fellow of the American Association for the Advancement of Science (AAAS), 2008

Best Publications

  • One-step gene disruption in yeast

    Rodney J. Rothstein

  • The double-strand-break repair model for recombination

    Jack W. Szostak;Terry L. Orr-Weaver;Rodney J. Rothstein;Franklin W. Stahl

  • Elevated recombination rates in transcriptionally active DNA.

    Barbara J. Thomas;Rodney Rothstein

  • Yeast transformation: a model system for the study of recombination

    Terry L. Orr-Weaver;Jack W. Szostak;Rodney J. Rothstein

  • Targeting, disruption, replacement, and allele rescue: integrative DNA transformation in yeast.

    Rodney Rothstein

  • Choreography of the DNA damage response: Spatiotemporal relationships among checkpoint and repair proteins

    Michael Lisby;Jacqueline H. Barlow;Rebecca C. Burgess;Rodney Rothstein

  • Repair of strand breaks by homologous recombination.

    Maria Jasin;Rodney Rothstein

  • A Suppressor of Two Essential Checkpoint Genes Identifies a Novel Protein that Negatively Affects dNTP Pools

    Xiaolan Zhao;Eric G.D Muller;Rodney Rothstein

  • The yeast type I topoisomerase Top3 interacts with Sgs1, a DNA helicase homolog: a potential eukaryotic reverse gyrase.

    Serge Gangloff;J Mcdonald;C Bendixen;L Arthur

  • A hyper-recombination mutation in S. cerevisiae identifies a novel eukaryotic topoisomerase

    John W. Wallis;Gary Chrebet;Gary Brodsky;Mark Rolfe

  • DNA strand annealing is promoted by the yeast Rad52 protein

    Uffe H. Mortensen;Christian Bendixen;Ivana Sunjevaric;Rodney Rothstein

  • Genetic applications of yeast transformation with linear and gapped plasmids.

    Terry L. Orr-Weaver;Jack W. Szostak;Rodney J. Rothstein

  • Survival of DNA damage in yeast directly depends on increased dNTP levels allowed by relaxed feedback inhibition of ribonucleotide reductase.

    Andrei Chabes;Bilyana Georgieva;Vladimir Domkin;Xiaolan Zhao

  • Rad52 forms DNA repair and recombination centers during S phase

    Michael Lisby;Rodney Rothstein;Uffe H. Mortensen

  • Colocalization of multiple DNA double-strand breaks at a single Rad52 repair centre.

    Michael Lisby;Uffe H. Mortensen;Rodney Rothstein

  • Increased chromosome mobility facilitates homology search during recombination.

    Judith Miné-Hattab;Rodney Rothstein

  • The Smc5–Smc6 complex and SUMO modification of Rad52 regulates recombinational repair at the ribosomal gene locus

    Jordi Torres-Rosell;Ivana Sunjevaric;Giacomo De Piccoli;Meik Sacher

  • HDACs link the DNA damage response, processing of double-strand breaks and autophagy

    Thomas Robert;Fabio Vanoli;Irene Chiolo;Ghadeer Shubassi

  • Replication fork pausing and recombination or "gimme a break".

    Rodney Rothstein;Bénédicte Michel;Serge Gangloff

  • The RecQ DNA Helicases in DNA Repair

    Kara A. Bernstein;Serge Gangloff;Rodney Rothstein

Frequent Co-Authors

Michael Lisby
Michael Lisby University of Copenhagen
Patrick Sung
Patrick Sung The University of Texas Health Science Center at San Antonio
Lorraine S. Symington
Lorraine S. Symington Columbia University
René Bernards
René Bernards Antoni van Leeuwenhoek Hospital
Xavier Darzacq
Xavier Darzacq University of California, Berkeley
Lumir Krejci
Lumir Krejci Masaryk University
Argiris Efstratiadis
Argiris Efstratiadis Biomedical Research Foundation of the Academy of Athens
Andrés Aguilera
Andrés Aguilera University of Seville
Jack W. Szostak
Jack W. Szostak University of Chicago
Lars Thelander
Lars Thelander Umeå University

If you think any of the details on this page are incorrect, let us know.

Report an issue

We appreciate your kind effort to assist us to improve this page, it would be helpful providing us with as much detail as possible in the text box below:

Related Online Degrees & Career Pathways

Studying Genetics in the USA can open doors to a wide range of related careers and advanced degree options. Many students choose to combine genetics with healthcare to expand their opportunities and impact. If you’re considering alternative pathways, there are several flexible online programs to explore.

For those interested in nursing, some nursing colleges that don’t require SAT or other major entrance exams may provide a quicker way to get started. Alternatively, students seeking rapid entry into healthcare might want to check out fast track LPN programs for online, accelerated credentials.

Those planning on moving into healthcare management can take advantage of some of the cheapest MHA programs online healthcare to prepare for leadership roles. If you are interested in advanced research or education, there are also PhD nursing programs offering flexible and affordable ways to achieve the highest academic credentials.

Exploring these related online degrees expands your possible career pathways, enhances your skillset, and provides more ways to apply genetics expertise in the evolving world of healthcare.

Best Scientists Citing Rodney Rothstein

Trending Scientists

Recently Published Articles