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Genetics

D-Index
129
Citations
59613
World Ranking
264
National Ranking
138

Research.com Recognitions

  • 2013 - Member of the National Academy of Medicine (NAM)
  • 2008 - Fellow of the American Academy of Arts and Sciences
  • 2000 - Member of the National Academy of Sciences
  • 1996 - Charles S. Mott Prize, General Motors Cancer Research Foundation

Overview

Richard D. Kolodner is affiliated with the University of California, San Diego in the United States. Their research primarily focuses on biochemistry, genetics, and molecular biology, as well as medicine.

Their work spans several subfields of study, including molecular biology, pathology and forensic medicine, plant science, oncology, and genetics. Key topics in their research include DNA repair mechanisms, genetic factors in colorectal cancer, CRISPR and genetic engineering, RNA research and splicing, RNA modifications and cancer, plant genetic and mutation studies, and BRCA gene mutations in cancer.

Among recent publications authored or co-authored by Kolodner are the following:

  • Tumour predisposition and cancer syndromes as models to study gene-environment interactions, 2020, Nature reviews. Cancer
  • FEN1 endonuclease as a therapeutic target for human cancers with defects in homologous recombination, 2020, Proceedings of the National Academy of Sciences
  • Ligation of newly replicated DNA controls the timing of DNA mismatch repair, 2021, Current Biology
  • Rad27 and Exo1 function in different excision pathways for mismatch repair in Saccharomyces cerevisiae, 2021, Nature Communications
  • Mechanisms underlying genome instability mediated by formation of foldback inversions in Saccharomyces cerevisiae, 2020, eLife

Their frequent co-authors include Christopher D. Putnam, Bin-Zhong Li, Felipe A. Calil, Kendall A. Torres, and Matthew L. DuPrie.

Publication venues with multiple contributions from Kolodner consist of Proceedings of the National Academy of Sciences, Nature reviews. Cancer, Current Biology, Nature Communications, and eLife.

Richard D. Kolodner's research contributions have been recognized by various professional societies. Their awards include membership in the National Academy of Sciences (2000), fellowship in the American Academy of Arts and Sciences (2008), membership in the National Academy of Medicine (2013), and the Charles S. Mott Prize from the General Motors Cancer Research Foundation in 1996.

Best Publications

  • The human mutator gene homolog MSH2 and its association with hereditary nonpolyposis colon cancer.

    Richard Fishel;Mary Kay Lescoe;M.R.S. Rao;Neal G. Copeland

  • Mutation in the DNA mismatch repair gene homologue hMLH 1 is associated with hereditary non-polyposis colon cancer

    Bronner Ce;Baker Sm;Morrison Pt;Warren G

  • Incidence and functional consequences of hMLH1 promoter hypermethylation in colorectal carcinoma

    James G. Herman;Asad Umar;Kornelia Polyak;Jeremy R. Graff

  • Mutation of a new gene encoding a putative pyrin-like protein causes familial cold autoinflammatory syndrome and Muckle–Wells syndrome

    Hal M. Hoffman;James L. Mueller;David H. Broide;Alan A. Wanderer

  • Methylation of the hMLH1 Promoter Correlates with Lack of Expression of hMLH1 in Sporadic Colon Tumors and Mismatch Repair-defective Human Tumor Cell Lines

    Kane Mf;Loda M;Gaida Gm;Lipman J

  • α-Synuclein Blocks ER-Golgi Traffic and Rab1 Rescues Neuron Loss in Parkinson's Models

    Antony A. Cooper;Aaron D. Gitler;Anil Cashikar;Cole M. Haynes

  • Eukaryotic DNA mismatch repair.

    Richard D Kolodner;Gerald T Marsischky

  • Saccharomyces Ku70, Mre11/Rad50, and RPA Proteins Regulate Adaptation to G2/M Arrest after DNA Damage

    Sang Eun Lee;J.Kent Moore;Allyson Holmes;Keiko Umezu

  • The evolution of genes: the chicken preproinsulin gene

    Francine Perler;Argiris Efstratiadis;Peter Lomedico;Walter Gilbert

  • Biochemistry and genetics of eukaryotic mismatch repair.

    R Kolodner

  • hMSH2 forms specific mispair-binding complexes with hMSH3 and hMSH6

    Samir Acharya;Teresa Wilson;Scott Gradia;Michael F. Kane

  • Meiotic Pachytene Arrest in MLH1-Deficient Mice

    Winfried Edelmann;Paula E Cohen;Michael Kane;Kirkland Lau

  • Redundancy of Saccharomyces cerevisiae MSH3 and MSH6 in MSH2-dependent mismatch repair.

    Gerald T. Marsischky;Nicole Filosi;Michael F. Kane;Richard Kolodner

  • Maintenance of genome stability in Saccharomyces cerevisiae.

    Richard D. Kolodner;Christopher D. Putnam;Kyungjae Myung

  • The structure and evolution of the two nonallelic rat preproinsulin genes

    Peter Lomedico;Nadia Rosenthal;Argiris Efstratiadis;Walter Gilbert

  • Identification and characterization of Saccharomyces cerevisiae EXO1, a gene encoding an exonuclease that interacts with MSH2

    Daniel X. Tishkoff;Adrienne L. Boerger;Pascale Bertrand;Nicole Filosi

  • Rewiring of genetic networks in response to DNA damage

    Sourav Bandyopadhyay;Monika Mehta;Dwight Kuo;Min Kyung Sung

  • MutS homolog 4 localization to meiotic chromosomes is required for chromosome pairing during meiosis in male and female mice

    Burkhard Kneitz;Paula E. Cohen;Elena Avdievich;Liyin Zhu

  • A Novel Mutation Avoidance Mechanism Dependent on S. cerevisiae RAD27 Is Distinct from DNA Mismatch Repair

    Daniel X. Tishkoff;Nicole Filosi;Gretchen M. Gaida;Richard D. Kolodner

  • Gross chromosomal rearrangements in Saccharomyces cerevisiae replication and recombination defective mutants.

    Clark Chen;Richard D. Kolodner

Frequent Co-Authors

Christopher D. Putnam
Christopher D. Putnam University of California, San Diego
Huilin Zhou
Huilin Zhou University of California, San Diego
Winfried Edelmann
Winfried Edelmann Albert Einstein College of Medicine
Raju Kucherlapati
Raju Kucherlapati Harvard University
Judy Garber
Judy Garber Harvard University
Arshad Desai
Arshad Desai University of California, San Diego
Kyungjae Myung
Kyungjae Myung Institute for Basic Science
Wolf Dietrich Heyer
Wolf Dietrich Heyer University of California, Davis
Arlen W. Johnson
Arlen W. Johnson The University of Texas at Austin
Hal M. Hoffman
Hal M. Hoffman University of California, San Diego

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