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D-Index & Metrics

Biology and Biochemistry

D-Index
49
Citations
9405
World Ranking
17984
National Ranking
7360

Overview

Christopher D. Putnam is affiliated with the University of California, San Diego in the United States. Their research spans significant areas in biochemistry, genetics, and molecular biology, as well as medicine. The main fields of study include:

  • Biochemistry, Genetics and Molecular Biology
  • Medicine

Their work engages deeply with specific subfields such as:

  • Molecular Biology
  • Pathology and Forensic Medicine
  • Immunology
  • Plant Science
  • Genetics

Research topics commonly explored by Christopher D. Putnam include:

  • DNA Repair Mechanisms
  • Genetic factors in colorectal cancer
  • CRISPR and Genetic Engineering
  • RNA Research and Splicing
  • Immunodeficiency and Autoimmune Disorders
  • Blood disorders and treatments
  • Immune Response and Inflammation

Among the recent publications involving Christopher D. Putnam are the following papers, which highlight contributions both as a primary author and collaborator:

  • "FEN1 endonuclease as a therapeutic target for human cancers with defects in homologous recombination," 2020, Proceedings of the National Academy of Sciences
  • "Immunodeficiency and bone marrow failure with mosaic and germline TLR8 gain of function," 2020, Blood
  • "Strand discrimination in DNA mismatch repair," 2021, DNA repair
  • "Variant STAT4 and Response to Ruxolitinib in an Autoinflammatory Syndrome," 2023, New England Journal of Medicine
  • "Ligation of newly replicated DNA controls the timing of DNA mismatch repair," 2021, Current Biology

The scientist frequently publishes in certain venues, indicating ongoing contributions to these research communities:

  • Proceedings of the National Academy of Sciences
  • bioRxiv (Cold Spring Harbor Laboratory)
  • DNA repair
  • Blood
  • New England Journal of Medicine

Christopher D. Putnam collaborates regularly with several researchers in the field, including:

  • Richard D. Kolodner
  • Bin-Zhong Li
  • Lori Broderick
  • Felipe A. Calil
  • Hal M. Hoffman

Best Publications

  • X-ray solution scattering (SAXS) combined with crystallography and computation: defining accurate macromolecular structures, conformations and assemblies in solution.

    Christopher D. Putnam;Michal Hammel;Greg L. Hura;John A. Tainer

  • Active and inhibited human catalase structures: ligand and NADPH binding and catalytic mechanism.

    Christopher D Putnam;Andrew S Arvai;Yves Bourne;John A Tainer

  • Maintenance of genome stability in Saccharomyces cerevisiae.

    Richard D. Kolodner;Christopher D. Putnam;Kyungjae Myung

  • The clinical continuum of cryopyrinopathies: novel CIAS1 mutations in North American patients and a new cryopyrin model.

    Ivona Aksentijevich;Christopher D. Putnam;Elaine F. Remmers;James L. Mueller

  • Inflammasome-Mediated Disease Animal Models Reveal Roles for Innate but Not Adaptive Immunity

    Susannah D. Brydges;Susannah D. Brydges;James L. Mueller;James L. Mueller;Matthew D. McGeough;Carla A. Pena

  • Evolution and mechanism from structures of an ADP-ribosylating toxin and NAD complex.

    Seungil Han;Joyce A. Craig;Christopher D. Putnam;Nadine B. Carozzi

  • Mechanism and ,energetics of green fluorescent protein chromophore synthesis revealed by trapped intermediate structures

    David P. Barondeau;Christopher D. Putnam;Carey J. Kassmann;John A. Tainer

  • Structure and mechanism of the RuvB Holliday junction branch migration motor.

    Christopher D Putnam;Sheila B Clancy;Hiro Tsuruta;Susana Gonzalez

  • DNA REPAIR MECHANISMS FOR THE RECOGNITION AND REMOVAL OF DAMAGED DNA BASES

    Clifford D. Mol;Sudip S. Parikh;Christopher D. Putnam;Terence P. Lo

  • DNA double-strand break repair from head to tail.

    Karl Peter Hopfner;Christopher D Putnam;John A Tainer

  • Mutation in Rpa1 results in defective DNA double-strand break repair, chromosomal instability and cancer in mice

    Yuxun Wang;Christopher D. Putnam;Michael F. Kane;Weijia Zhang

  • Protein mimicry of DNA from crystal structures of the uracil-DNA glycosylase inhibitor protein and its complex with Escherichia coli uracil-DNA glycosylase

    Christopher D Putnam;Mary Jane N Shroyer;Amy J Lundquist;Clifford D Mol

  • Specific pathways prevent duplication-mediated genome rearrangements

    Christopher D. Putnam;Tikvah K. Hayes;Richard D. Kolodner

  • Exonuclease 1-dependent and independent mismatch repair.

    Eva M. Goellner;Christopher D. Putnam;Richard D. Kolodner

  • Lessons learned from structural results on uracil-DNA glycosylase

    Sudip S Parikh;Christopher D Putnam;John A Tainer

  • The N Terminus of Saccharomyces cerevisiae Msh6 Is an Unstructured Tether to PCNA

    Scarlet S. Shell;Christopher D. Putnam;Richard D. Kolodner

  • Chromosome healing by de novo telomere addition in Saccharomyces cerevisiae.

    Vincent Pennaneach;Christopher D. Putnam;Richard D. Kolodner

  • The RNA polymerase I transcription factor UBF is a sequence-tolerant HMG-box protein that can recognize structured nucleic acids

    Gregory P. Copenhaver;Christopher D. Putnam;Michael L. Denton;Craig S. Pikaard

  • Mismatch Repair, But Not Heteroduplex Rejection, Is Temporally Coupled to DNA Replication

    Hans Hombauer;Anjana Srivatsan;Christopher D. Putnam;Richard D. Kolodner

  • DNA REPAIR MECHANISMS FOR THE RECOGNITION AND REMOVAL OF DAMAGED

    Clifford D. Mol;Sudip S. Parikh;Christopher D. Putnam;Terence P. Lo

Frequent Co-Authors

Richard D. Kolodner
Richard D. Kolodner University of California, San Diego
John A. Tainer
John A. Tainer The University of Texas MD Anderson Cancer Center
Hal M. Hoffman
Hal M. Hoffman University of California, San Diego
Huilin Zhou
Huilin Zhou University of California, San Diego
Arshad Desai
Arshad Desai University of California, San Diego
Andrew S. Arvai
Andrew S. Arvai Scripps Research Institute
Gregory P. Copenhaver
Gregory P. Copenhaver University of North Carolina at Chapel Hill
Craig S. Pikaard
Craig S. Pikaard Indiana University
Eicke Latz
Eicke Latz German Rheumatism Research Centre
Daniel L. Kastner
Daniel L. Kastner National Institutes of Health

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