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Juan P. Bolaños

Juan P. Bolaños

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Biology and Biochemistry
Spain
2023

D-Index & Metrics

Biology and Biochemistry

D-Index
71
Citations
18996
World Ranking
6611
National Ranking
108

Research.com Recognitions

  • 2023 - Research.com Biology and Biochemistry in Spain Leader Award

Overview

Juan P. Bolaños is a researcher affiliated with the University of Salamanca in Spain. Their work primarily focuses on biochemistry, genetics, molecular biology, and medicine, with specific emphasis on molecular biology, physiology, cellular and molecular neuroscience, biochemistry, and neurology.

The scientist's research spans several interconnected topics, including:

  • Mitochondrial Function and Pathology
  • Neuroscience and Neuropharmacology Research
  • Adipose Tissue and Metabolism
  • Neuroinflammation and Neurodegeneration Mechanisms
  • Autophagy in Disease and Therapy
  • Amino Acid Enzymes and Metabolism
  • Lysosomal Storage Disorders Research

Juan P. Bolaños has contributed to numerous scientific publications, with frequent appearances in venues such as Free Radical Biology and Medicine, bioRxiv (Cold Spring Harbor Laboratory), Nature Metabolism, Nature Communications, and IBRO Neuroscience Reports.

Their recent papers include:

  • "Astrocyte-neuron metabolic cooperation shapes brain activity," 2021, Cell Metabolism
  • "Glucose metabolism links astroglial mitochondria to cannabinoid effects," 2020, Nature
  • "Fatty acid oxidation organizes mitochondrial supercomplexes to sustain astrocytic ROS and cognition," 2023, Nature Metabolism
  • "Cross-talk between energy and redox metabolism in astrocyte-neuron functional cooperation," 2023, Essays in Biochemistry
  • "l-Serine links metabolism with neurotransmission," 2020, Progress in Neurobiology

Juan P. Bolaños collaborates frequently with several researchers, including:

  • Daniel Jiménez-Blasco
  • Ángeles Almeida
  • Carlos Vicente-Gutiérrez
  • Rebeca Lapresa
  • Marina García-Macía

Best Publications

  • The bioenergetic and antioxidant status of neurons is controlled by continuous degradation of a key glycolytic enzyme by APC/C–Cdh1

    Angel Herrero-Mendez;Angeles Almeida;Emilio Fernández;Carolina Maestre

  • Nitric oxide-mediated mitochondrial damage in the brain: mechanisms and implications for neurodegenerative diseases

    Juan P. Bolaños;Angeles Almeida;Victoria Stewart;Stephan Peuchen

  • Nitric oxide, cell bioenergetics and neurodegeneration.

    Salvador Moncada;Juan P. Bolaños

  • Effect of peroxynitrite on the mitochondrial respiratory chain: differential susceptibility of neurones and astrocytes in primary culture.

    Juan P. Bolaños;Simon J. R. Heales;John M. Land;John B. Clark

  • Nitric oxide, mitochondria and neurological disease.

    Simon J.R. Heales;Juan P. Bolaños;Victoria C. Stewart;Paul S. Brookes

  • Nitric oxide switches on glycolysis through the AMP protein kinase and 6-phosphofructo-2-kinase pathway.

    Angeles Almeida;Salvador Moncada;Juan P. Bolaños

  • Complex I assembly into supercomplexes determines differential mitochondrial ROS production in neurons and astrocytes.

    Irene Lopez-Fabuel;Juliette Le Douce;Angela Logan;Andrew M. James

  • Nitric oxide-mediated inhibition of the mitochondrial respiratory chain in cultured astrocytes.

    J. P. Bolaños;S. Peuchen;S. J. R. Heales;J. M. Land

  • Different responses of astrocytes and neurons to nitric oxide: the role of glycolytically generated ATP in astrocyte protection.

    Angeles Almeida;Julia Almeida;Juan P. Bolaños;Salvador Moncada

  • Astrocyte-neuron metabolic cooperation shapes brain activity

    Gilles Bonvento;Juan P. Bolaños

  • Roles of nitric oxide in brain hypoxia-ischemia.

    Juan P Bolaños;Angeles Almeida

  • Glycolysis: a bioenergetic or a survival pathway?

    Juan P. Bolaños;Angeles Almeida;Salvador Moncada

  • Nitric oxide-mediated mitochondrial damage: A potential neuroprotective role for glutathione

    Juan P. Bolaños;Simon J.R. Heales;Stefan Peuchen;Jane E. Barker

  • Mitochondrial respiratory chain and free radical generation in stroke.

    María A Moro;Angeles Almeida;Juan P Bolaños;Ignacio Lizasoain

  • Antioxidant and bioenergetic coupling between neurons and astrocytes.

    Seila Fernandez-Fernandez;Angeles Almeida;Juan P. Bolaños

  • Antioxidants, reactive oxygen and nitrogen species, gene induction and mitochondrial function.

    Malcolm J. Jackson;Sergio Papa;Juan Bolaños;Richard Bruckdorfer

  • Glucose metabolism links astroglial mitochondria to cannabinoid effects

    Daniel Jimenez-Blasco;Daniel Jimenez-Blasco;Arnau Busquets-Garcia;Arnau Busquets-Garcia;Etienne Hebert-Chatelain;Roman Serrat;Roman Serrat

  • Oxygen and glucose deprivation induces mitochondrial dysfunction and oxidative stress in neurones but not in astrocytes in primary culture.

    Angeles Almeida;María Delgado-Esteban;Juan P. Bolaños;José M. Medina

  • Bioenergetics and redox adaptations of astrocytes to neuronal activity

    Juan P. Bolaños

  • Nitric oxide produced by activated astrocytes rapidly and reversibly inhibits cellular respiration.

    Guy C. Brown;Juan P. Bolaños;Simon J.R. Heales;John B. Clark

Frequent Co-Authors

Simon J. R. Heales
Simon J. R. Heales University College London
John B. Clark
John B. Clark University College London
John M. Land
John M. Land University College London
Salvador Moncada
Salvador Moncada University of Manchester
José Castillo
José Castillo University of Santiago de Compostela
Gilles Bonvento
Gilles Bonvento University of Paris-Saclay
Michael P. Murphy
Michael P. Murphy University of Cambridge
Michael R. Duchen
Michael R. Duchen University College London
José Antonio Enríquez
José Antonio Enríquez Spanish National Centre for Cardiovascular Research
Pedro Grandes
Pedro Grandes University of the Basque Country

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