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Biology and Biochemistry

D-Index
56
Citations
15707
World Ranking
14211
National Ranking
21

Overview

Béla Melegh is affiliated with the University of Pecs in Hungary and has contributed extensively to the fields of biochemistry, genetics, molecular biology, and medicine. Their research primarily focuses on genetics, molecular biology, neurology, cellular and molecular neuroscience, and physiology. This breadth spans 43 publications in biochemistry, genetics, and molecular biology, alongside 41 in medicine.

The scientist's work encompasses several main topics including genetic neurodegenerative diseases, genomics and rare diseases, mitochondrial function and pathology, traumatic brain injury and neurovascular disturbances, BRCA gene mutations in cancer, amyotrophic lateral sclerosis research, and trauma and emergency care studies. These areas are reflected in the diverse range of papers and collaborations associated with Melegh.

Notable recent papers authored or co-authored by Béla Melegh include:

  • Cancer Surveillance Guideline for individuals with PTEN hamartoma tumour syndrome, 2020, European Journal of Human Genetics
  • Neurofilaments in spinocerebellar ataxia type 3: blood biomarkers at the preataxic and ataxic stage in humans and mice, 2020, EMBO Molecular Medicine
  • Fluid balance and outcome in critically ill patients with traumatic brain injury (CENTER-TBI and OzENTER-TBI): a prospective, multicentre, comparative effectiveness study, 2021, The Lancet Neurology
  • The use of polygenic risk scores in pre-implantation genetic testing: an unproven, unethical practice, 2021, European Journal of Human Genetics
  • Conversion of individuals at risk for spinocerebellar ataxia types 1, 2, 3, and 6 to manifest ataxia (RISCA): a longitudinal cohort study, 2020, The Lancet Neurology

Their frequent co-authors illustrate ongoing collaborative efforts in research. Colleagues they often work with include Jon Infante, Lüdger Schöls, Holger Hengel, Kathrin Reetz, and Alexandra Dürr, with collaboration frequencies ranging from 9 to 11 joint publications.

Publications by Melegh appear predominantly in the European Journal of Human Genetics, where there are eight contributions. Other common venues include Frontiers in Public Health and The Cerebellum, each with three publications, and The Lancet Neurology and Frontiers in Genetics, both with two publications respectively.

Best Publications

  • Biological insights from 108 schizophrenia-associated genetic loci

    Stephan Ripke;Stephan Ripke;Benjamin M. Neale;Benjamin M. Neale;Aiden Corvin;James T. R. Walters

  • Traumatic brain injury: integrated approaches to improve prevention, clinical care, and research

    Andrew I R Maas;David K Menon;P David Adelson;Nada Andelic

  • Ancient human genomes suggest three ancestral populations for present-day Europeans

    Iosif Lazaridis;Iosif Lazaridis;Nick Patterson;Alissa Mittnik;Gabriel Renaud

  • Modeling Linkage Disequilibrium Increases Accuracy of Polygenic Risk Scores

    Bjarni J. Vilhjálmsson;Jian Yang;Hilary K. Finucane;Alexander Gusev

  • Genomic Dissection of Bipolar Disorder and Schizophrenia, Including 28 Subphenotypes

    Douglas M. Ruderfer;Stephan Ripke;Stephan Ripke;Stephan Ripke;Andrew McQuillin;James Boocock

  • Partitioning heritability of regulatory and cell-type-specific variants across 11 common diseases

    Alexander Gusev;S. Hong Lee;Gosia Trynka;Hilary Finucane

  • Increase in viral gastroenteritis outbreaks in Europe and epidemic spread of new norovirus variant

    Ben Lopman;Harry Vennema;Evelyne Kohli;Pierre Pothier

  • Case-mix, care pathways, and outcomes in patients with traumatic brain injury in CENTER-TBI: a European prospective, multicentre, longitudinal, cohort study

    Ewout W. Steyerberg;Ewout W. Steyerberg;Eveline Wiegers;Charlie Sewalt;Andras Buki

  • Genetic structure of Europeans: a view from the North-East

    Mari Nelis;Mari Nelis;Tõnu Esko;Tõnu Esko;Reedik Mägi;Fritz Zimprich

  • Parallel palaeogenomic transects reveal complex genetic history of early European farmers.

    Mark Lipson;Anna Szécsényi-Nagy;Swapan Mallick;Swapan Mallick;Annamária Pósa

  • Spinocerebellar ataxia types 1, 2, 3, and 6 Disease severity and nonataxia symptoms

    T Schmitz-Hübsch;M Coudert;Peter Bauer;P Giunti

  • Long-term disease progression in spinocerebellar ataxia types 1, 2, 3, and 6: a longitudinal cohort study

    Heike Jacobi;Sophie Tezenas du Montcel;Peter Bauer;Paola Giunti

  • Complement genes contribute sex-biased vulnerability in diverse disorders

    Nolan Kamitaki;Nolan Kamitaki;Aswin Sekar;Aswin Sekar;Robert E. Handsaker;Robert E. Handsaker;Heather de Rivera;Heather de Rivera

  • Guidelines for the Li–Fraumeni and heritable TP53-related cancer syndromes

    Thierry Frebourg;Svetlana Bajalica Lagercrantz;Carla Oliveira;Rita Magenheim

  • Tracing past human male movements in northern/eastern Africa and western Eurasia: new clues from Y-chromosomal haplogroups E-M78 and J-M12.

    Fulvio Cruciani;Roberta La Fratta;Beniamino Trombetta;Piero Santolamazza

  • Biological and clinical characteristics of individuals at risk for spinocerebellar ataxia types 1, 2, 3, and 6 in the longitudinal RISCA study: analysis of baseline data

    Heike Jacobi;Kathrin Reetz;Kathrin Reetz;Sophie Tezenas du Montcel;Peter Bauer

  • Reliability and validity of the International Cooperative Ataxia Rating Scale: A study in 156 spinocerebellar ataxia patients

    Tanja T. Schmitz-Hübsch;Sophie Tezenas S.T. du Montcel;Laszlo L. Baliko;Sylvia S. Boesch

  • Modulation of the age at onset in spinocerebellar ataxia by CAG tracts in various genes

    Sophie Tezenas Du Montcel;Sophie Tezenas Du Montcel;Alexandra Durr;Peter Bauer;Karla P. Figueroa

  • Gene expression imputation across multiple brain regions provides insights into schizophrenia risk

    Laura M. Huckins;Amanda Dobbyn;Douglas M. Ruderfer;Gabriel Hoffman

  • Role of carnitine and its derivatives in the development and management of type 2 diabetes.

    Judit Bene;Kinga Hadzsiev;Bela Melegh

Frequent Co-Authors

Thomas Klockgether
Thomas Klockgether German Center for Neurodegenerative Diseases
Alexandra Durr
Alexandra Durr Sorbonne University
Dagmar Timmann
Dagmar Timmann University of Duisburg-Essen
Tonu Esko
Tonu Esko University of Tartu
Paola Giunti
Paola Giunti University College London
Aarno Palotie
Aarno Palotie University of Helsinki
Massimo Pandolfo
Massimo Pandolfo McGill University
Ludger Schöls
Ludger Schöls University of Tübingen
Krisztián Bányai
Krisztián Bányai University of Pecs
Tune H. Pers
Tune H. Pers University of Copenhagen

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