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José M. López-Novoa

José M. López-Novoa

D-Index & Metrics

Medicine

D-Index
72
Citations
18252
World Ranking
19848
National Ranking
285

Overview

José M. López-Novoa is affiliated with the University of Salamanca in Spain. Their research spans multiple fields within medicine, with a focus on molecular biology, nephrology, obstetrics and gynecology, pulmonary and respiratory medicine, and epidemiology. The body of work consists of 12 publications in medicine and 4 in biochemistry, genetics, and molecular biology.

The scientist's work addresses diverse topics that include pregnancy and preeclampsia studies, angiogenesis and VEGF in cancer, TGF-β signaling in diseases, cancer, hypoxia and metabolism, acute kidney injury research, chronic kidney disease and diabetes, and dialysis and renal disease management.

Recent significant publications by José M. López-Novoa include:

  • Continuous endoglin (CD105) overexpression disrupts angiogenesis and facilitates tumor cell metastasis, 2020, Angiogenesis
  • Impaired Tubular Reabsorption Is the Main Mechanism Explaining Increases in Urinary NGAL Excretion Following Acute Kidney Injury in Rats, 2020, Toxicological Sciences
  • Potential Role of Circulating Endoglin in Hypertension via the Upregulated Expression of BMP4, 2020, Cells
  • Pregnancy-Induced High Plasma Levels of Soluble Endoglin in Mice Lead to Preeclampsia Symptoms and Placental Abnormalities, 2020, International Journal of Molecular Sciences
  • Functional Alterations Involved in Increased Bleeding in Hereditary Hemorrhagic Telangiectasia Mouse Models, 2022, Frontiers in Medicine

Frequent coauthors include Miguel Pericacho, Alicia Rodríguez-Barbero, Carmelo Bernabéu, Claudia Ollauri-Ibáñez, and Elena Núñez-Gómez. Collaborations with these researchers have resulted in multiple joint publications.

Publication venues where José M. López-Novoa has contributed include:

  • Angiogenesis
  • Toxicological Sciences
  • International Journal of Molecular Sciences
  • Cells
  • Frontiers in Medicine

The research contributed by José M. López-Novoa covers molecular mechanisms and pathological processes relevant to kidney injury, vascular biology, and pregnancy-related conditions, among others. This multidisciplinary approach integrates clinical and molecular insights within their research scope.

Best Publications

  • New insights into the mechanism of aminoglycoside nephrotoxicity: an integrative point of view

    Jose M. Lopez-Novoa;Yaremi Quiros;Laura Vicente;Ana I. Morales

  • Inflammation and EMT: an alliance towards organ fibrosis and cancer progression

    Jose Miguel López-Novoa;M Angela Nieto

  • Snail1-induced partial epithelial-to-mesenchymal transition drives renal fibrosis in mice and can be targeted to reverse established disease

    M Teresa Grande;Berta Sánchez-Laorden;Cristina López-Blau;Cristina A De Frutos

  • Role of TGF-β in chronic kidney disease: an integration of tubular, glomerular and vascular effects

    Francisco J. López-Hernández;Jose M. López-Novoa

  • The emerging role of TGF-β superfamily coreceptors in cancer

    Carmelo Bernabeu;Jose M. Lopez-Novoa;Miguel Quintanilla

  • Glomerular nephrotoxicity of aminoglycosides.

    Carlos Martínez-Salgado;Francisco J. López-Hernández;José M. López-Novoa

  • Metformin prevents experimental gentamicin-induced nephropathy by a mitochondria-dependent pathway

    Ana I. Morales;Dominique Detaille;Marta Prieto;Angel Puente

  • Fibroblast activation and myofibroblast generation in obstructive nephropathy

    María T. Grande;José M. López-Novoa

  • An Integrative Overview on the Mechanisms Underlying the Renal Tubular Cytotoxicity of Gentamicin

    Yaremi Quiros;Laura Vicente-Vicente;Ana I Morales;José M López-Novoa

  • The physiological role of endoglin in the cardiovascular system.

    José M. López-Novoa;Carmelo Bernabeu

  • An integrative view of the pathophysiological events leading to cisplatin nephrotoxicity

    Penélope D Sánchez-González;Francisco J López-Hernández;José M López-Novoa;Ana I Morales

  • Protective effect of quercetin on experimental chronic cadmium nephrotoxicity in rats is based on its antioxidant properties.

    A.I. Morales;C. Vicente-Sánchez;J.M. Santiago Sandoval;J. Egido

  • Etiopathology of chronic tubular, glomerular and renovascular nephropathies: Clinical implications

    José M López-Novoa;José M López-Novoa;Ana B Rodríguez-Peña;Alberto Ortiz;Carlos Martínez-Salgado

  • In vivo bradykinin B2 receptor activation reduces renal fibrosis

    Joost P. Schanstra;Eric Neau;Pascale Drogoz;Miguel A. Arevalo Gomez

  • Endoglin regulates nitric oxide-dependent vasodilatation

    Mirjana Jerkic;Juan V. Rivas-Elena;Marta Prieto;Rosalía Carrón

  • Common pathophysiological mechanisms of chronic kidney disease: Therapeutic perspectives

    José M. López-Novoa;Carlos Martínez-Salgado;Ana B. Rodríguez-Peña;Francisco J. López Hernández

  • Role of inflammation in túbulo-interstitial damage associated to obstructive nephropathy

    María T Grande;María T Grande;Fernando Pérez-Barriocanal;Fernando Pérez-Barriocanal;José M López-Novoa;José M López-Novoa

  • Endothelial endoglin is involved in inflammation: role in leukocyte adhesion and transmigration

    Elisa Rossi;Francisco Sanz-Rodriguez;Nélida Eleno;Annette Düwell

  • Quercetin reduces cisplatin nephrotoxicity in rats without compromising its anti-tumour activity

    Penelope D. Sanchez-Gonzalez;Francisco J. Lopez-Hernandez;Fernando Perez-Barriocanal;Ana I. Morales

  • An integrative view on the role of TGF-β in the progressive tubular deletion associated with chronic kidney disease

    Omar García-Sánchez;Francisco J. López-Hernández;José M. López-Novoa

Frequent Co-Authors

Carmelo Bernabeu
Carmelo Bernabeu Spanish National Research Council
Ana Olivera
Ana Olivera National Institutes of Health
Eugenio Santos
Eugenio Santos University of Salamanca
Santiago Lamas
Santiago Lamas Spanish National Research Council
Miguel Quintanilla
Miguel Quintanilla Spanish National Research Council
Michelle Letarte
Michelle Letarte University of Toronto
Atanasio Pandiella
Atanasio Pandiella Spanish National Research Council
Alberto Ortiz
Alberto Ortiz Autonomous University of Madrid
Marta Ruiz-Ortega
Marta Ruiz-Ortega Autonomous University of Madrid
Giovanni Camussi
Giovanni Camussi University of Turin

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