Marie-José Goumans spends much of his time researching Cell biology, Transforming growth factor, SMAD, Internal medicine and Signal transduction. In his research on the topic of Cell biology, BMPR2 is strongly related with Cellular differentiation. The Transforming growth factor study combines topics in areas such as Endoglin and Receptor complex.
His SMAD research includes themes of R-SMAD, Transcription factor, Bone morphogenetic protein and Kinase activity. His study in Internal medicine is interdisciplinary in nature, drawing from both Endocrinology, Mesenchymal stem cell and Cardiology. While the research belongs to areas of Transforming growth factor beta, he spends his time largely on the problem of Angiogenesis, intersecting his research to questions surrounding Endothelial stem cell and Activin receptor.
Cell biology, Internal medicine, Progenitor cell, Stem cell and Cardiology are his primary areas of study. The study incorporates disciplines such as Receptor, Angiogenesis and Cellular differentiation in addition to Cell biology. His research in Angiogenesis intersects with topics in Endothelial stem cell, Vascular endothelial growth factor, Endoglin and Pathology.
His research on Internal medicine frequently links to adjacent areas such as Endocrinology. Marie-José Goumans has included themes like Regenerative medicine, Paracrine signalling, Adult stem cell, Myocyte and Transplantation in his Progenitor cell study. His work carried out in the field of Stem cell brings together such families of science as Embryonic stem cell, Cell culture, Immunology and Bioinformatics.
Marie-José Goumans mostly deals with Cell biology, Internal medicine, Cancer research, Pulmonary hypertension and Cardiology. His Cell biology research incorporates themes from Paracrine signalling and Transplantation. He has included themes like Maladaptation and Endocrinology in his Internal medicine study.
His Cancer research research includes themes of Endothelial stem cell, BMPR2, Bone morphogenetic protein, Signalling and Signal transduction. The Signal transduction study combines topics in areas such as Transforming growth factor, Thrombosis, Venous thrombosis and Gene knockdown. His studies deal with areas such as Endoglin and Pathology as well as Angiogenesis.
His main research concerns Cancer research, Bone morphogenetic protein, Cell biology, Pulmonary hypertension and Angiogenesis. Marie-José Goumans has researched Cancer research in several fields, including Endothelial stem cell, BMPR2, Receptor, Biomarker and Transforming growth factor. His work in Endothelial stem cell addresses issues such as Cell type, which are connected to fields such as Signal transduction.
His Bone morphogenetic protein study also includes fields such as
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Balancing the activation state of the endothelium via two distinct TGF‐β type I receptors
Marie‐José Goumans;Gudrun Valdimarsdottir;Susumu Itoh;Alexander Rosendahl.
The EMBO Journal (2002)
Activin Receptor-like Kinase (ALK)1 Is an Antagonistic Mediator of Lateral TGFβ/ALK5 Signaling
Marie José Goumans;Gudrun Valdimarsdottir;Susumu Itoh;Franck Lebrin.
Molecular Cell (2003)
Signaling of transforming growth factor‐β family members through Smad proteins
Susumu Itoh;Fumiko Itoh;Marie‐José Goumans;Peter ten Dijke.
FEBS Journal (2000)
Endoglin promotes endothelial cell proliferation and TGF‐β/ALK1 signal transduction
Franck Lebrin;Marie-José Goumans;Marie-José Goumans;Leon Jonker;Rita L C Carvalho.
The EMBO Journal (2004)
Abnormal angiogenesis but intact hematopoietic potential in TGF-beta type I receptor-deficient mice.
Jonas Larsson;Marie-José Goumans;Lottie Jansson Sjöstrand;Marga A. van Rooijen.
The EMBO Journal (2001)
Regulation of cell proliferation by Smad proteins.
Peter Ten Dijke;Marie-José Goumans;Fumiko Itoh;Susumu Itoh.
Journal of Cellular Physiology (2002)
TGF-beta signaling in vascular biology and dysfunction.
Marie-José Goumans;Zhen Liu;Peter ten Dijke.
Cell Research (2009)
Functional analysis of the TGFbeta receptor/Smad pathway through gene ablation in mice.
Marie-José Goumans;Christine Mummery.
The International Journal of Developmental Biology (2000)
Signaling by members of the TGF-β family in vascular morphogenesis and disease
Evangelia Pardali;Marie-José Goumans;Peter ten Dijke.
Trends in Cell Biology (2010)
Controlling the Angiogenic Switch: A Balance between Two Distinct TGF-b Receptor Signaling Pathways
Marie-Jose Goumans;Franck Lebrin;Gudrun Valdimarsdottir.
Trends in Cardiovascular Medicine (2003)
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