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Biology and Biochemistry
Netherlands
2023

D-Index & Metrics

Biology and Biochemistry

D-Index
92
Citations
28626
World Ranking
2225
National Ranking
48

Research.com Recognitions

  • 2023 - Research.com Biology and Biochemistry in Netherlands Leader Award

Overview

Marie-José Goumans is affiliated with Leiden University Medical Center in the Netherlands. Their research primarily spans the fields of Medicine and Biochemistry, Genetics and Molecular Biology, with a strong emphasis on subfields such as Pulmonary and Respiratory Medicine, Cardiology and Cardiovascular Medicine, Molecular Biology, Surgery, and Genetics.

The scientist's work focuses on several main topics within biomedical research, including:

  • Pulmonary Hypertension Research and Treatments
  • Tissue Engineering and Regenerative Medicine
  • Congenital Heart Defects Research
  • Cardiac Fibrosis and Remodeling
  • Cardiac Valve Diseases and Treatments
  • Electrospun Nanofibers in Biomedical Applications
  • Heterotopic Ossification and Related Conditions

Recent publications by Marie-José Goumans highlight their contributions to understanding vascular biology and pulmonary diseases. Notable papers include:

  • TGF-β-Induced Endothelial to Mesenchymal Transition in Disease and Tissue Engineering (2020), published in Frontiers in Cell and Developmental Biology
  • Cellular senescence impairs the reversibility of pulmonary arterial hypertension (2020), published in Science Translational Medicine
  • Endothelial Dysfunction in Pulmonary Hypertension: Cause or Consequence? (2021), published in Biomedicines
  • Endoglin: Beyond the Endothelium (2020), published in Biomolecules
  • Bone morphogenetic protein receptors: Structure, function and targeting by selective small molecule kinase inhibitors (2020), published in Bone

Throughout their career, Marie-José Goumans has frequently collaborated with several scientists, including:

  • Harm Jan Bogaard
  • Anke M. Smits
  • Gonzalo Sánchez-Duffhues
  • Frances S. de Man
  • Anton Vonk Noordegraaf

Publications are often featured in prominent biomedical journals, with a concentration of works appearing in:

  • Cardiovascular Research
  • Circulation
  • European Heart Journal
  • Cells
  • bioRxiv (Cold Spring Harbor Laboratory)

Best Publications

  • Balancing the activation state of the endothelium via two distinct TGF‐β type I receptors

    Marie‐José Goumans;Gudrun Valdimarsdottir;Susumu Itoh;Alexander Rosendahl

  • Activin Receptor-like Kinase (ALK)1 Is an Antagonistic Mediator of Lateral TGFβ/ALK5 Signaling

    Marie José Goumans;Gudrun Valdimarsdottir;Susumu Itoh;Franck Lebrin

  • Signaling of transforming growth factor-β family members through Smad proteins

    Susumu Itoh;Fumiko Itoh;Marie‐José Goumans;Peter ten Dijke

  • Endoglin promotes endothelial cell proliferation and TGF‐β/ALK1 signal transduction

    Franck Lebrin;Marie-José Goumans;Marie-José Goumans;Leon Jonker;Rita L C Carvalho

  • TGF-beta signaling in vascular biology and dysfunction.

    Marie-José Goumans;Zhen Liu;Peter ten Dijke

  • Abnormal angiogenesis but intact hematopoietic potential in TGF-beta type I receptor-deficient mice.

    Jonas Larsson;Marie-José Goumans;Lottie Jansson Sjöstrand;Marga A. van Rooijen

  • Regulation of cell proliferation by Smad proteins.

    Peter Ten Dijke;Marie-José Goumans;Fumiko Itoh;Susumu Itoh

  • Defined Engineered Human Myocardium With Advanced Maturation for Applications in Heart Failure Modeling and Repair.

    Malte Tiburcy;James E. Hudson;Paul Balfanz;Susanne Schlick

  • Signaling by members of the TGF-β family in vascular morphogenesis and disease

    Evangelia Pardali;Marie-José Goumans;Peter ten Dijke

  • Functional analysis of the TGFbeta receptor/Smad pathway through gene ablation in mice.

    Marie-José Goumans;Christine Mummery

  • Human mesenchymal stem cell-conditioned medium improves cardiac function following myocardial infarction

    Leo Timmers;Sai Kiang Lim;Imo E. Hoefer;Fatih Arslan

  • Controlling the Angiogenic Switch: A Balance between Two Distinct TGF-b Receptor Signaling Pathways

    Marie-Jose Goumans;Franck Lebrin;Gudrun Valdimarsdottir

  • Endoglin in angiogenesis and vascular diseases

    Peter ten Dijke;Marie-José Goumans;Evangelia Pardali

  • Toll-Like Receptor 4 Mediates Maladaptive Left Ventricular Remodeling and Impairs Cardiac Function After Myocardial Infarction

    Leo Timmers;Joost P.G. Sluijter;J. Karlijn van Keulen;Imo E. Hoefer

  • Transforming growth factor β signal transduction

    Sylviane Dennler;Marie-José Goumans;Peter ten Dijke

  • MicroRNA-1 and -499 Regulate Differentiation and Proliferation in Human-Derived Cardiomyocyte Progenitor Cells

    Joost P.G. Sluijter;Alain van Mil;Patrick van Vliet;Corina H.G. Metz

  • Stimulation of Id1 Expression by Bone Morphogenetic Protein Is Sufficient and Necessary for Bone Morphogenetic Protein–Induced Activation of Endothelial Cells

    Gudrun Valdimarsdottir;Marie-José Goumans;Alexander Rosendahl;Martijn Brugman

  • Human cardiomyocyte progenitor cells differentiate into functional mature cardiomyocytes: an in vitro model for studying human cardiac physiology and pathophysiology

    Anke M Smits;Anke M Smits;Patrick van Vliet;Corina H Metz;Tom Korfage

  • Higher functionality of extracellular vesicles isolated using size-exclusion chromatography compared to ultracentrifugation

    Emma A. Mol;Marie José Goumans;Pieter A. Doevendans;Joost P.G. Sluijter

  • Increase in ALK1/ALK5 ratio as a cause for elevated MMP-13 expression in osteoarthritis in humans and mice.

    Esmeralda N. Blaney Davidson;Dennis F. G. Remst;Elly L. Vitters;Henk M. van Beuningen

Frequent Co-Authors

Pieter A. Doevendans
Pieter A. Doevendans Utrecht University
Joost P.G. Sluijter
Joost P.G. Sluijter Utrecht University
Peter ten Dijke
Peter ten Dijke Leiden University Medical Center
Christine L. Mummery
Christine L. Mummery Leiden University Medical Center
Gerard Pasterkamp
Gerard Pasterkamp Utrecht University
Robert E. Poelmann
Robert E. Poelmann Leiden University
Paul H.A. Quax
Paul H.A. Quax Leiden University Medical Center
Susumu Itoh
Susumu Itoh Showa Pharmaceutical University
Stefan Karlsson
Stefan Karlsson Lund University
Martin J. Schalij
Martin J. Schalij Leiden University Medical Center

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