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Danny Huylebroeck

Danny Huylebroeck

D-Index & Metrics

Molecular Biology

D-Index
77
Citations
20756
World Ranking
1114
National Ranking
29

Overview

Danny Huylebroeck is affiliated with the Erasmus MC in the Netherlands, focusing primarily on research within biochemistry, genetics, molecular biology, and medicine. The scientist's work covers various subfields including molecular biology, genetics, immunology, surgery, and oncology.

The range of topics across their publications highlights research interests in:

  • Genomics and Chromatin Dynamics
  • Glioma Diagnosis and Treatment
  • Single-cell and Spatial Transcriptomics
  • Cancer Cells and Metastasis
  • Microtubule and Mitosis Dynamics
  • Congenital Gastrointestinal and Neural Anomalies
  • Pluripotent Stem Cells Research

Some recent notable papers include:

  • Heterogeneity and clonal relationships of adaptive immune cells in ulcerative colitis revealed by single-cell analyses, 2020, Science Immunology
  • Cardiomyocytes stimulate angiogenesis after ischemic injury in a ZEB2-dependent manner, 2021, Nature Communications
  • Steroid-resistant human inflammatory ILC2s are marked by CD45RO and elevated in type 2 respiratory diseases, 2021, Science Immunology
  • The EMT Transcription Factor ZEB2 Promotes Proliferation of Primary and Metastatic Melanoma While Suppressing an Invasive, Mesenchymal-Like Phenotype, 2020, Cancer Research
  • Interplay between the EMT Transcription Factors ZEB1 and ZEB2 regulates hematopoietic stem and progenitor cell differentiation and hematopoietic lineage fidelity, 2021, PLoS Biology

The scientist frequently collaborates with several co-authors, notably:

  • Wilfred F. J. van IJcken
  • Andrea Conidi
  • Rutger W. W. Brouwer
  • Anne L. Korporaal
  • Frank Grosveld

Thebody of published work appears in multiple prominent venues, including:

  • bioRxiv (Cold Spring Harbor Laboratory)
  • Neuro-Oncology
  • Science Immunology
  • Nature Communications
  • Cancer Research

Best Publications

  • The Two-Handed E Box Binding Zinc Finger Protein SIP1 Downregulates E-Cadherin and Induces Invasion

    Joke Comijn;Geert Berx;Petra Vermassen;Kristin Verschueren

  • Identification of a potent Xenopus mesoderm-inducing factor as a homologue of activin A.

    J C Smith;B M Price;K Van Nimmen;Danny Huylebroeck

  • Presenilin 2 deficiency causes a mild pulmonary phenotype and no changes in amyloid precursor protein processing but enhances the embryonic lethal phenotype of presenilin 1 deficiency

    An Herreman;Dieter Hartmann;Wim Annaert;Paul Saftig

  • Osteogenic protein-1 binds to activin type II receptors and induces certain activin-like effects.

    H Yamashita;P ten Dijke;D Huylebroeck;T K Sampath

  • SIP1, a novel zinc finger/homeodomain repressor, interacts with Smad proteins and binds to 5'-CACCT sequences in candidate target genes.

    Kristin Verschueren;Jacques E. Remacle;Clara Collart;Clara Collart;Harry Kraft;Harry Kraft

  • In vitro mutagenesis of a full-length cDNA clone of Semliki Forest virus: the small 6,000-molecular-weight membrane protein modulates virus release

    P Liljeström;S Lusa;Danny Huylebroeck;H Garoff

  • Smad5 knockout mice die at mid-gestation due to multiple embryonic and extraembryonic defects

    H Chang;Danny Huylebroeck;K Verschueren;Qiuxia Guo

  • Loss-of-function mutations in LEMD3 result in osteopoikilosis, Buschke-Ollendorff syndrome and melorheostosis.

    Jan Hellemans;Olena Preobrazhenska;Andy Willaert;Philippe Debeer

  • Distinct spatial and temporal expression patterns of two type I receptors for bone morphogenetic proteins during mouse embryogenesis

    N Dewulf;K Verschueren;O Lonnoy;A Morén

  • Mice lacking ZFHX1B, the gene that codes for Smad-interacting protein-1, reveal a role for multiple neural crest cell defects in the etiology of Hirschsprung disease-mental retardation syndrome.

    Tom Van de Putte;Mitsuji Maruhashi;Annick Francis;Lucien Nelles

  • Endocardial cushion and myocardial defects after cardiac myocyte-specific conditional deletion of the bone morphogenetic protein receptor ALK3

    Vinciane Gaussin;Tom Van de Putte;Yuji Mishina;Mark C. Hanks

  • New mode of DNA binding of multi‐zinc finger transcription factors: δEF1 family members bind with two hands to two target sites

    Jacques E. Remacle;Harry Kraft;Walter Lerchner;Gunther Wuytens

  • Epidermal differentiation does not involve the pro-apoptotic executioner caspases, but is associated with caspase-14 induction and processing.

    Saskia Lippens;M Kockx;M Knaapen;L Mortier

  • The mammalian gene function resource: the international knockout mouse consortium

    Allan Bradley;Konstantinos Anastassiadis;Abdelkader Ayadi;James F. Battey

  • Antigenic drift between the haemagglutinin of the Hong Kong influenza strains A/Aichi/2/68 and A/Victoria/3/75.

    Martine Verhoeyen;Rongxiang Fang;Willy Min Jou;René Devos

  • Follistatins neutralize activin bioactivity by inhibition of activin binding to its type II receptors.

    J. P. De Winter;P. Ten Dijke;C. J. M. De Vries;T. A. E. Van Achterberg

  • Complete structure of the hemagglutinin gene from the human influenza A/Victoria/3/75 (H3N2) strain as determined from cloned DNA

    Willy Min Jou;Martine Verhoeyen;René Devos;Eric Saman

  • Overexpression of activin A in the skin of transgenic mice reveals new activities of activin in epidermal morphogenesis, dermal fibrosis and wound repair.

    Barbara Munz;Barbara Munz;Hans Smola;Felix Engelhardt;Felix Engelhardt;Kerstin Bleuel

  • Heterozygous missense mutations in SMARCA2 cause Nicolaides-Baraitser syndrome

    Jeroen K.J. Van Houdt;Beata Anna Nowakowska;Sérgio B. Sousa;Sérgio B. Sousa;Barbera D.C. Van Schaik

  • Stalk Cell Phenotype Depends on Integration of Notch and Smad1/5 Signaling Cascades

    Iván M. Moya;Lieve Umans;Elke Maas;Paulo N.G. Pereira

Frequent Co-Authors

An Zwijsen
An Zwijsen KU Leuven
Jody J. Haigh
Jody J. Haigh University of Manitoba
James C. Smith
James C. Smith The Francis Crick Institute
Geert Berx
Geert Berx Ghent University
Walter Fiers
Walter Fiers Ghent University
Leo A. van Grunsven
Leo A. van Grunsven Vrije Universiteit Brussel
Hisato Kondoh
Hisato Kondoh Kyoto Sangyo University

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