World's Best Scientists 2026 revealed!

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Biology and Biochemistry

D-Index
58
Citations
10441
World Ranking
13335
National Ranking
5673

Research.com Recognitions

  • 2014 - Fellow of the American Association for the Advancement of Science (AAAS)

Overview

Margaret Kielian is affiliated with the Albert Einstein College of Medicine in the United States. Their research is primarily focused in the field of Medicine, with a substantial emphasis on Infectious Diseases, Public Health, Environmental and Occupational Health, Epidemiology, Virology, and Plant Science. The scientist's body of work covers several main topics including mosquito-borne diseases and control, viral infections and vectors, viral infections and outbreaks research, HIV research and treatment, virology and viral diseases, plant virus research studies, and SARS-CoV-2 and COVID-19 research.

Several recent publications highlight Margaret Kielian's contributions to the study of viral mechanisms and infectious diseases. These include:

  • Enhancing host cell infection by SARS-CoV-2, 2020, published in Science
  • Multiple capsid protein binding sites mediate selective packaging of the alphavirus genomic RNA, 2020, published in Nature Communications
  • Berberine Chloride is an Alphavirus Inhibitor That Targets Nucleocapsid Assembly, 2020, published in mBio
  • Near-germline human monoclonal antibodies neutralize and protect against multiple arthritogenic alphaviruses, 2021, published in Proceedings of the National Academy of Sciences
  • Chikungunya virus cell-to-cell transmission is mediated by intercellular extensions in vitro and in vivo, 2023, published in Nature Microbiology

Margaret Kielian often collaborates with other researchers, including Peiqi Yin, Pratyush Kumar Das, Rebecca S. Brown, Caroline Martin, and Thomas E. Morrison. These frequent co-authorships indicate ongoing partnerships in the field of virology and infectious diseases.

The scientist has a notable presence in key scientific journals, with frequent publications in mBio, Viruses, Journal of Virology, Proceedings of the National Academy of Sciences, and PLoS Pathogens. This reflects a consistent contribution to the literature on virology and infectious diseases.

Margaret Kielian's work has been recognized through professional accolades, including being named a Fellow of the American Association for the Advancement of Science (AAAS) in 2014. This fellowship acknowledges participation and standing within the broader scientific community.

Best Publications

  • Membrane fusion proteins of enveloped animal viruses.

    Judith White;Margaret Kielian;Ari Helenius

  • Virus membrane-fusion proteins: more than one way to make a hairpin.

    Margaret Kielian;Félix A. Rey;Félix A. Rey

  • Conformational change and protein-protein interactions of the fusion protein of Semliki Forest virus.

    Don L. Gibbons;Don L. Gibbons;Marie Christine Vaney;Alain Roussel;Armelle Vigouroux

  • Class II virus membrane fusion proteins.

    Margaret Kielian

  • Role of cholesterol in fusion of Semliki Forest virus with membranes.

    M C Kielian;A Helenius

  • pH-induced alterations in the fusogenic spike protein of Semliki Forest virus.

    Margaret Kielian;Ari Helenius

  • Cholesterol is required for infection by Semliki Forest virus.

    Thomas Phalen;Margaret Kielian

  • The cholesterol requirement for sindbis virus entry and exit and characterization of a spike protein region involved in cholesterol dependence.

    Yanping E. Lu;Todd Cassese;Margaret Kielian

  • Acidification of endosome subpopulations in wild-type Chinese hamster ovary cells and temperature-sensitive acidification-defective mutants.

    Sandra Schmid;Renate Fuchs;Margaret Kielian;Ari Helenius

  • Alphavirus Entry and Membrane Fusion.

    Margaret Kielian;Chantal Chanel-Vos;Maofu Liao

  • Membrane fusion And the Alphavirus Life Cycle

    Margaret Kielian

  • Mutagenesis of the putative fusion domain of the Semliki Forest virus spike protein.

    P Levy-Mintz;M Kielian

  • A Single Point Mutation Controls the Cholesterol Dependence of Semliki Forest Virus Entry and Exit

    Malini Vashishtha;Thomas Phalen;Marianne T. Marquardt;Jae S. Ryu

  • The Fusion Peptide of Semliki Forest Virus Associates with Sterol-Rich Membrane Domains

    Anna Ahn;Don Lynn Gibbons;Margaret Kielian

  • Mechanisms of enveloped virus entry into cells.

    Kielian M;Jungerwirth S

  • Wortmannin-sensitive Trafficking Pathways in Chinese Hamster Ovary Cells DIFFERENTIAL EFFECTS ON ENDOCYTOSIS AND LYSOSOMAL SORTING

    Jayme L. Martys;Christina Wjasow;Dawn M. Gangi;Margaret C. Kielian

  • Domain III from class II fusion proteins functions as a dominant-negative inhibitor of virus membrane fusion

    Maofu Liao;Margaret Kielian

  • Dealing with low pH: entry and exit of alphaviruses and flaviviruses

    Claudia Sánchez San Martín;Catherine Y. Liu;Margaret Kielian

  • Flaviviruses: braking the entering

    Theodore C Pierson;Margaret Kielian

  • Phagosome-lysosome fusion. Characterization of intracellular membrane fusion in mouse macrophages

    Margaret C. Kielian;Margaret C. Kielian;Zanvil A. Cohn

Frequent Co-Authors

Ari Helenius
Ari Helenius ETH Zurich
Zanvil A. Cohn
Zanvil A. Cohn Rockefeller University
Félix A. Rey
Félix A. Rey Institut Pasteur
Fredric S. Cohen
Fredric S. Cohen Rush University Medical Center
Don L. Gibbons
Don L. Gibbons The University of Texas MD Anderson Cancer Center
Ira Mellman
Ira Mellman Parker Institute for Cancer Immunotherapy
Kartik Chandran
Kartik Chandran Albert Einstein College of Medicine
John M. Dye
John M. Dye United States Army Medical Research Institute of Infectious Diseases
Markus R. Wenk
Markus R. Wenk Hamad bin Khalifa University
Sushil K. Satija
Sushil K. Satija National Institute of Standards and Technology

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