His primary scientific interests are in Lipid bilayer fusion, Virology, Liposome, Biophysics and Vesicle. His Lipid bilayer fusion research includes elements of Viral envelope, Synthetic membrane and Biological membrane. His Virology study frequently draws connections to adjacent fields such as Immunology.
The various areas that Jan Wilschut examines in his Liposome study include Conformational change and Viral membrane. Jan Wilschut has researched Biophysics in several fields, including Membrane fluidity, Phosphatidylserine and Peptide. The study incorporates disciplines such as Crystallography, Bilayer and Phospholipid, Phosphatidylcholine in addition to Vesicle.
His primary areas of study are Virology, Immunology, Lipid bilayer fusion, Virus and Vaccination. The concepts of his Virology study are interwoven with issues in Virosome, Antibody, Antigen and Immunogenicity. His Antigen research incorporates themes from Cytotoxic T cell and Antigen presentation.
His studies in Lipid bilayer fusion integrate themes in fields like Semliki Forest virus, Vesicle, Biophysics and Liposome. His Biophysics research is multidisciplinary, incorporating perspectives in Membrane and Membrane Fusion Activity. His research investigates the link between Vaccination and topics such as Cervical cancer that cross with problems in Gynecology.
Jan Wilschut focuses on Vaccination, Virology, Immunology, Virus and Influenza vaccine. When carried out as part of a general Vaccination research project, his work on Vaccine efficacy is frequently linked to work in Demography, therefore connecting diverse disciplines of study. His Virology research includes elements of Antibody, Antigen, Immune system, Immunogenicity and Adjuvant.
His Antigen research includes themes of Viral envelope and Influenza A virus. His biological study spans a wide range of topics, including Cytotoxic T cell and Semliki Forest virus. His Chronic hepatitis study in the realm of Virus connects with subjects such as CpG Oligodeoxynucleotide.
Jan Wilschut mostly deals with Virology, Immunology, Virus, Vaccination and Antibody. His Virology study combines topics from a wide range of disciplines, such as Cytotoxic T cell and T cell. Immunity, Adjuvant, Immunogenicity, Antigen and Influenza vaccine are among the areas of Immunology where Jan Wilschut concentrates his study.
His study in Immune system extends to Virus with its themes. Jan Wilschut interconnects Cervical cancer, Gynecology, MEDLINE and Cost-effectiveness analysis in the investigation of issues within Vaccination. His work on Antibody-dependent enhancement as part of general Dengue virus study is frequently linked to Transmission, therefore connecting diverse disciplines of science.
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FLUORESCENCE METHOD FOR MEASURING THE KINETICS OF FUSION BETWEEN BIOLOGICAL-MEMBRANES
Dick Hoekstra;T Deboer;Katharina Klappe;Jan Wilschut.
Studies on the mechanism of membrane fusion: kinetics of calcium ion induced fusion of phosphatidylserine vesicles followed by a new assay for mixing of aqueous vesicle contents.
Jan Wilschut;Nejat Duzgunes;Robert Fraley;Demetrios Papahadjopoulos.
Dissecting the cell entry pathway of dengue virus by single-particle tracking in living cells.
Hilde M. van der Schaar;Michael J. Rust;Chen Chen;Heidi van der Ende-Metselaar.
PLOS Pathogens (2008)
Dengue virus life cycle: viral and host factors modulating infectivity
Izabela A. Rodenhuis-Zybert;Jan Wilschut;Jolanda M. Smit.
Cellular and Molecular Life Sciences (2010)
Calcium/magnesium specificity in membrane fusion: kinetics of aggregation and fusion of phosphatidylserine vesicles and the role of bilayer curvature
Jan Wilschut;Nejat Duzgunes;Demetrios Papahadjopoulos.
Superior Immunogenicity of Inactivated Whole Virus H5N1 Influenza Vaccine is Primarily Controlled by Toll-like Receptor Signalling
Felix Geeraedts;Nadege Goutagny;Veit Hornung;Martina Severa.
PLOS Pathogens (2008)
The virosome concept for influenza vaccines
Anke Huckriede;Laura Bungener;Toon Stegmann;Toos Daemen.
Immature Dengue Virus: A Veiled Pathogen?
Izabela A. Rodenhuis-Zybert;Hilde M. Van Der Schaar;Júlia M. Da Silva Voorham;Heidi Van Der Ende-Metselaar.
PLOS Pathogens (2010)
Flavivirus cell entry and membrane fusion.
Jolanda M. Smit;Bastiaan Moesker;Izabela Rodenhuis-Zybert;Jan Wilschut.
Membrane fusion of Semliki Forest virus involves homotrimers of the fusion protein.
J M Wahlberg;R Bron;J Wilschut;H Garoff.
Journal of Virology (1992)
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