D-Index & Metrics Best Publications

D-Index & Metrics D-index (Discipline H-index) only includes papers and citation values for an examined discipline in contrast to General H-index which accounts for publications across all disciplines.

Discipline name D-index D-index (Discipline H-index) only includes papers and citation values for an examined discipline in contrast to General H-index which accounts for publications across all disciplines. Citations Publications World Ranking National Ranking
Biology and Biochemistry D-index 53 Citations 8,201 131 World Ranking 8565 National Ranking 199

Overview

What is he best known for?

The fields of study he is best known for:

  • Enzyme
  • Biochemistry
  • DNA

His primary scientific interests are in Liposome, Biochemistry, Phosphatidylcholine, Vesicle and Molecular biology. His study in Liposome is interdisciplinary in nature, drawing from both Biophysics, Chromatography and Drug carrier. His Biochemistry research is multidisciplinary, relying on both Kupffer cell and Cell biology.

His Phosphatidylcholine study deals with Incubation intersecting with Lipoprotein and Lipoprotein particle. His work deals with themes such as Phospholipase, Phospholipase A2, Crystallography and Substrate, which intersect with Vesicle. His Molecular biology study combines topics in areas such as Glycolipid, Lactosylceramide and Endothelial stem cell.

His most cited work include:

  • Liposomes in the Therapy of Infectious Disease and Cancer (586 citations)
  • Accelerated Blood Clearance and Altered Biodistribution of Repeated Injections of Sterically Stabilized Liposomes (365 citations)
  • A potential role of macrophage activation in the treatment of cancer. (289 citations)

What are the main themes of his work throughout his whole career to date?

Gerrit L. Scherphof mainly focuses on Liposome, Biochemistry, In vitro, Phosphatidylcholine and Molecular biology. His studies in Liposome integrate themes in fields like Vesicle, Biophysics, Phosphatidylserine, Kupffer cell and Drug carrier. His research integrates issues of Targeted drug delivery and Cell biology in his study of Drug carrier.

His studies deal with areas such as Lipopolysaccharide, Antibody and Intracellular as well as In vitro. The concepts of his Phosphatidylcholine study are interwoven with issues in Phospholipase, Chromatography and Albumin. His Muramyl dipeptide research also works with subjects such as

  • Cytotoxic T cell which is related to area like Immunology and Cancer research,
  • Macrophage that connect with fields like Tumor necrosis factor alpha,
  • Toxicity most often made with reference to Pharmacology.

He most often published in these fields:

  • Liposome (70.16%)
  • Biochemistry (45.55%)
  • In vitro (17.80%)

What were the highlights of his more recent work (between 2002-2018)?

  • Liposome (70.16%)
  • Molecular biology (16.75%)
  • Biochemistry (45.55%)

In recent papers he was focusing on the following fields of study:

Gerrit L. Scherphof mainly investigates Liposome, Molecular biology, Biochemistry, Scavenger receptor and In vitro. His Liposome research includes elements of Biophysics, Blood proteins, Albumin, Pharmacology and Drug carrier. His work carried out in the field of Molecular biology brings together such families of science as Covalent bond, Plasmid dna, Transfection, Gene delivery and Colorectal cancer.

The various areas that Gerrit L. Scherphof examines in his Biochemistry study include Cationic liposome and Hepatic stellate cell. He works mostly in the field of Scavenger receptor, limiting it down to topics relating to Receptor and, in certain cases, Cell growth, Adenocarcinoma and Cell, as a part of the same area of interest. His In vitro research includes themes of Kupffer cell and Immunology.

Between 2002 and 2018, his most popular works were:

  • The role of apolipoprotein E in the elimination of liposomes from blood by hepatocytes in the mouse (75 citations)
  • Interaction of differently designed immunoliposomes with colon cancer cells and Kupffer cells. An in vitro comparison (44 citations)
  • Interaction of targeted liposomes with primary cultured hepatic stellate cells: Involvement of multiple receptor systems (41 citations)

In his most recent research, the most cited papers focused on:

  • Enzyme
  • Biochemistry
  • DNA

His primary scientific interests are in Biochemistry, Liposome, Hepatic stellate cell, Mannose 6-phosphate and Scavenger receptor. His Biochemistry research incorporates elements of Immunoliposome and Pharmacokinetics. By researching both Liposome and Nucleotide, Gerrit L. Scherphof produces research that crosses academic boundaries.

Gerrit L. Scherphof combines subjects such as Fibrosis and Cell biology with his study of Hepatic stellate cell. His research investigates the connection with Mannose 6-phosphate and areas like Molecular biology which intersect with concerns in Asialoglycoprotein receptor and In vitro. His Drug carrier study combines topics from a wide range of disciplines, such as Biophysics, Biodistribution, Gene delivery and Doxorubicin.

This overview was generated by a machine learning system which analysed the scientist’s body of work. If you have any feedback, you can contact us here.

Best Publications

Liposomes in the Therapy of Infectious Disease and Cancer

Toos Daemen;M Hardonk;J Koudstaal;W oosterhuis.
alan R Liss, Inc (1988)

924 Citations

Accelerated Blood Clearance and Altered Biodistribution of Repeated Injections of Sterically Stabilized Liposomes

Els T. M. Dams;Peter Laverman;Wim J. G. Oyen;Gert Storm.
Journal of Pharmacology and Experimental Therapeutics (2000)

536 Citations

A potential role of macrophage activation in the treatment of cancer.

AH Klimp;de Elisabeth G. E. Vries;GL Scherphof;Toos Daemen.
Critical Reviews in Oncology Hematology (2002)

427 Citations

Disintegration of phosphatidylcholine liposomes in plasma as a result of interaction with high-density lipoproteins.

Gerrit Scherphof;Frits Roerdink;Moseley Waite;John Parks.
Biochimica et Biophysica Acta (1978)

323 Citations

POSITIONAL SPECIFICITY OF SATURATED AND UNSATURATED FATTY ACIDS IN PHOSPHATIDIC ACID FROM RAT LIVER

F. Possmayer;G.L. Scherphof;T.M.A.R. Dubbelman;L.M.G. Van Golde.
Biochimica et Biophysica Acta (1969)

252 Citations

Transfer of [14C]phosphatidylcholine between liposomes and human plasma high density lipoprotein Partial purification of a transfer-stimulating plasma factor using a rapid transfer assay

Jan Damen;Joke Regts;Gerrit Scherphof.
Biochimica et Biophysica Acta (1982)

219 Citations

FUNCTIONAL RECONSTITUTION OF INFLUENZA-VIRUS ENVELOPES

T. Stegmann;H. W. M. Morselt;F. P. Booy;J. F. L. Van Breemen.
The EMBO Journal (1987)

218 Citations

THE INVOLVEMENT OF PARENCHYMAL, KUPFFER AND ENDOTHELIAL LIVER-CELLS IN THE HEPATIC-UPTAKE OF INTRAVENOUSLY INJECTED LIPOSOMES - EFFECTS OF LANTHANUM AND GADOLINIUM SALTS

Frits Roerdink;Jan Dijkstra;Ger Hartman;Ben Bolscher.
Biochimica et Biophysica Acta (1981)

213 Citations

KINETICS OF PH-DEPENDENT FUSION BETWEEN INFLUENZA-VIRUS AND LIPOSOMES

Toon Stegmann;Dick Hoekstra;G Scherphof;Jan Wilschut.
Biochemistry (1985)

212 Citations

Transfer and exchange of phospholipid between small unilamellar liposomes and rat plasma high density lipoproteins : Dependence on cholesterol content and phospholipid composition

Jan Damen;Joke Regts;Gerrit Scherphof.
Biochimica et Biophysica Acta (1981)

210 Citations

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