His primary areas of study are Biochemistry, Internal medicine, Endocrinology, Hepatic stellate cell and Pharmacology. As part of his studies on Biochemistry, Dirk K.F. Meijer often connects relevant subjects like Organic anion. His work is dedicated to discovering how Internal medicine, Downregulation and upregulation are connected with Lipopolysaccharide, Multidrug resistance-associated protein 2 and Molecular biology and other disciplines.
Dirk K.F. Meijer focuses mostly in the field of Endocrinology, narrowing it down to topics relating to Inflammation and, in certain cases, Tissue inhibitor of metalloproteinase. Dirk K.F. Meijer has researched Hepatic stellate cell in several fields, including Fibrosis, Cell, Receptor and Cell biology. His research integrates issues of Excretion, Nephrotoxicity and Cyclodextrin in his study of Pharmacology.
His scientific interests lie mostly in Biochemistry, Pharmacology, Internal medicine, Endocrinology and Pharmacokinetics. Biochemistry and Drug carrier are commonly linked in his work. His studies deal with areas such as Drug delivery and Hepatic stellate cell as well as Pharmacology.
Metabolism and Perfusion are among the areas of Internal medicine where Dirk K.F. Meijer concentrates his study. His Fibrosis research extends to the thematically linked field of Endocrinology. His research on Pharmacokinetics frequently connects to adjacent areas such as Urine.
His primary areas of investigation include Hepatic stellate cell, In vitro, Internal medicine, Pharmacology and Biochemistry. His research in In vitro intersects with topics in Human serum albumin, Virus, Virology, Molecular biology and Gene delivery. He frequently studies issues relating to Endocrinology and Internal medicine.
The concepts of his Pharmacology study are interwoven with issues in Endothelial stem cell and Alkaline phosphatase. His Biochemistry study frequently links to other fields, such as Organic anion. His Pharmacokinetics research is multidisciplinary, incorporating perspectives in Chromatography and Metabolism.
His main research concerns Hepatic stellate cell, Internal medicine, Endocrinology, In vitro and Biochemistry. His work deals with themes such as Downregulation and upregulation, Alkaline phosphatase and Rho kinase inhibitor, which intersect with Internal medicine. His Endocrinology research is multidisciplinary, relying on both Reperfusion injury, Renal ischemia, Organic anion transporter 1 and Tissue inhibitor of metalloproteinase.
The In vitro study combines topics in areas such as Small intestine, Betaherpesvirinae, Human cytomegalovirus and Pharmacology, Drug. The various areas that Dirk K.F. Meijer examines in his Pharmacology study include Internalization and Immunoconjugate. Dirk K.F. Meijer combines topics linked to Organic anion with his work on Biochemistry.
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Limited oral bioavailability and active epithelial excretion of paclitaxel (Taxol) caused by P-glycoprotein in the intestine
A. Sparreboom;J. van Asperen;U. Mayer;A.H. Schinkel.
Proceedings of the National Academy of Sciences of the United States of America (1997)
Up-regulation of the multidrug resistance genes, Mrp1 and Mdr1b, and down-regulation of the organic anion transporter, Mrp2, and the bile salt transporter, Spgp, in endotoxemic rat liver
Thera A. Vos;Guido J. Hooiveld;Hans Koning;Sarah Childs.
Antiviral activities of lactoferrin
B.W.A van der Strate;L Beljaars;G Molema;M.C Harmsen.
Antiviral Research (2001)
Hepatobiliary secretion of organic compounds; molecular mechanisms of membrane transport.
Ronald P.J. Oude Elferink;Dirk K.F. Meijer;Folkert Kuipers;Peter L.M. Jansen.
Biochimica et Biophysica Acta (1995)
Antiviral Effects of Plasma and Milk Proteins: Lactoferrin Shows Potent Activity against Both Human Immunodeficiency Virus and Human Cytomegalovirus Replication In Vitro
Marco Harmsen;Pj Swart;Mp Debethune;R Pauwels.
The Journal of Infectious Diseases (1995)
MW/Pharm, an integrated software package for drug dosage regimen calculation and therapeutic drug monitoring
Johannes H. Proost;Dirk K.F. Meijer.
Computers in Biology and Medicine (1992)
Substantial excretion of digoxin via the intestinal mucosa and prevention of long-term digoxin accumulation in the brain by the mdrla P-glycoprotein
U Mayer;E Wagenaar;J.H Beijnen;J.W Smit.
British Journal of Pharmacology (1996)
Hepatic Uptake of the Magnetic Resonance Imaging Contrast Agent Gadoxetate by the Organic Anion Transporting Polypeptide Oatp1
J. E. Van Montfoort;B. Stieger;D. K. F. Meijer;H.-J. Weinmann.
Journal of Pharmacology and Experimental Therapeutics (1999)
Localization of organic anion transporting polypeptide 4 (Oatp4) in rat liver and comparison of its substrate specificity with Oatp1, Oatp2 and Oatp3.
Cattori;JE van Montfoort;B Stieger;L Landmann.
Pflügers Archiv: European Journal of Physiology (2001)
Drug uptake systems in liver and kidney
J. E. van Montfoort;B. Hagenbuch;G. M.M. Groothuis;H. Koepsell.
Current Drug Metabolism (2003)
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