Dirk K. F. Meijer

Overview

Best Publications

• Limited oral bioavailability and active epithelial excretion of paclitaxel (Taxol) caused by P-glycoprotein in the intestine

  A. Sparreboom;J. van Asperen;U. Mayer;A.H. Schinkel

  1124
  Citations

• Antiviral activities of lactoferrin

  B.W.A van der Strate;L Beljaars;G Molema;M.C Harmsen

  616
  Citations

• Antiviral Effects of Plasma and Milk Proteins: Lactoferrin Shows Potent Activity against Both Human Immunodeficiency Virus and Human Cytomegalovirus Replication In Vitro

  Marco Harmsen;Pj Swart;Mp Debethune;R Pauwels

  531
  Citations

• Up-regulation of the multidrug resistance genes, Mrp1 and Mdr1b, and down-regulation of the organic anion transporter, Mrp2, and the bile salt transporter, Spgp, in endotoxemic rat liver

  Thera A. Vos;Guido J. Hooiveld;Hans Koning;Sarah Childs

  531
  Citations

• Hepatobiliary secretion of organic compounds; molecular mechanisms of membrane transport.

  Ronald P.J. Oude Elferink;Dirk K.F. Meijer;Folkert Kuipers;Peter L.M. Jansen

  493
  Citations

• MW/Pharm, an integrated software package for drug dosage regimen calculation and therapeutic drug monitoring

  Johannes H. Proost;Dirk K.F. Meijer

  461
  Citations

• Substantial excretion of digoxin via the intestinal mucosa and prevention of long-term digoxin accumulation in the brain by the mdrla P-glycoprotein

  U Mayer;E Wagenaar;J.H Beijnen;J.W Smit

  362
  Citations

• Hepatic Uptake of the Magnetic Resonance Imaging Contrast Agent Gadoxetate by the Organic Anion Transporting Polypeptide Oatp1

  J. E. Van Montfoort;B. Stieger;D. K. F. Meijer;H.-J. Weinmann

  317
  Citations

• Localization of organic anion transporting polypeptide 4 (Oatp4) in rat liver and comparison of its substrate specificity with Oatp1, Oatp2 and Oatp3.

  Cattori;JE van Montfoort;B Stieger;L Landmann

  253
  Citations

• Removal of phosphate from lipid A as a strategy to detoxify lipopolysaccharide.

  Hafida Bentala;Willem R Verweij;Ali Huizinga-Van der Vlag;Annemiek M van Loenen-Weemaes

  247
  Citations

• Drug uptake systems in liver and kidney

  J. E. van Montfoort;B. Hagenbuch;G. M.M. Groothuis;H. Koepsell

  246
  Citations

• LPS-induced downregulation of MRP2 and BSEP in human liver is due to a posttranscriptional process

  Marieke G. L. Elferink;Peter Olinga;Annelies L. Draaisma;Marjolijn T. Merema

  223
  Citations

• Albumin modified with mannose 6-phosphate: A potential carrier for selective delivery of antifibrotic drugs to rat and human hepatic stellate cells.

  Leonie Beljaars;Grietje Molema;Betty Weert;Harmke Bonnema

  214
  Citations

• Preparation and functional evaluation of RGD-modified proteins as alpha(v)beta(3) integrin directed therapeutics.

  Robbert J Kok;Astrid J Schraa;Erwin J Bos;Henk E Moorlag

  209
  Citations

• The effect of parenterally administered cyclodextrins on cholesterol levels in the rat.

  Henderik W. Frijlink;Anko C. Eissens;Nanco R. Hefting;Klaas Poelstra

  195
  Citations

• Antiviral effects of milk proteins: Acylation results in polyanionic compounds with potent activity against human immunodeficiency virus types 1 and 2 in vitro

  P J Swart;M E Kuipers;C Smit;R Pauwels

  194
  Citations

• Successful Targeting to Rat Hepatic Stellate Cells Using Albumin Modified with Cyclic Peptides That Recognize the Collagen Type VI Receptor

  Leonie Beljaars;Grietje Molema;D Schuppan;A Geerts

  189
  Citations

• A Novel Strategy to Modify Adenovirus Tropism and Enhance Transgene Delivery to Activated Vascular Endothelial Cells In Vitro and In Vivo

  Ken Ichi Ogawara;Marianne G. Rots;Robbert J. Kok;Henk E. Moorlag

  178
  Citations

• Specific delivery of captopril to the kidney with the prodrug captopril-lysozyme.

  R. J. Kok;F. Grijpstra;R. B. Walthuis;F. Moolenaar

  176
  Citations

• Massive targeting of liposomes, surface-modified with anionized albumins, to hepatic endothelial cells

  Jan A. A. M. Kamps;Henriëtte W. M. Morselt;Pieter J. Swart;Dick K. F. Meijer

  175
  Citations