World's Best Scientists 2026 revealed!
Alisdair B. Boraston

Alisdair B. Boraston

D-Index & Metrics

Chemistry

D-Index
62
Citations
13578
World Ranking
8835
National Ranking
228

Biology and Biochemistry

D-Index
63
Citations
13771
World Ranking
10241
National Ranking
352

Overview

Alisdair B. Boraston is affiliated with the University of Victoria in Canada and specializes in the field of Biochemistry, Genetics and Molecular Biology. Their research spans several subfields including Molecular Biology, Biotechnology, Organic Chemistry, Aquatic Science, and Infectious Diseases.

The scientist's research concentrates on specific topics such as:

  • Enzyme Production and Characterization
  • Glycosylation and Glycoproteins Research
  • Carbohydrate Chemistry and Synthesis
  • Seaweed-derived Bioactive Compounds
  • Lysosomal Storage Disorders Research
  • Antibiotic Resistance in Bacteria
  • Antimicrobial Resistance in Staphylococcus

Alisdair B. Boraston has authored multiple papers, with recent publications including:

  • "The Glycoprotease CpaA Secreted by Medically Relevant Acinetobacter Species Targets Multiple O -Linked Host Glycoproteins" (2020), published in mBio
  • "Metabolism of a hybrid algal galactan by members of the human gut microbiome" (2022), published in Nature Chemical Biology
  • "The gastrointestinal pathogen Campylobacter jejuni metabolizes sugars with potential help from commensal Bacteroides vulgatus" (2020), published in Communications Biology
  • "The glycoconjugate-degrading enzymes of Clostridium perfringens: Tailored catalysts for breaching the intestinal mucus barrier" (2020), published in Glycobiology
  • "Architecturally complex O -glycopeptidases are customized for mucin recognition and hydrolysis" (2021), published in Proceedings of the National Academy of Sciences

Frequent collaborators in their work include:

  • Lila M. Gierasch
  • F. Peter Guengerich
  • Ruma Banerjee
  • Roger Colbran
  • Peter Cresswell

The scientist has published extensively in venues such as:

  • Journal of Biological Chemistry
  • bioRxiv (Cold Spring Harbor Laboratory)
  • Acta Crystallographica Section F Structural Biology Communications
  • Nature Chemical Biology
  • Glycobiology

Best Publications

  • Carbohydrate-binding modules: fine-tuning polysaccharide recognition

    Alisdair B. Boraston;David N. Bolam;Harry J. Gilbert;Gideon J. Davies

  • Human gut Bacteroidetes can utilize yeast mannan through a selfish mechanism

    Fiona Cuskin;Fiona Cuskin;Elisabeth C. Lowe;Max J. Temple;Yanping Zhu;Yanping Zhu

  • Advances in understanding the molecular basis of plant cell wall polysaccharide recognition by carbohydrate-binding modules.

    HJ Gilbert;JP Knox;AB Boraston

  • Pseudomonas cellulose-binding domains mediate their effects by increasing enzyme substrate proximity

    David N. Bolam;Antonio Ciruela;Simon McQUEEN-MASON;Peter Simpson

  • Bacteria of the human gut microbiome catabolize red seaweed glycans with carbohydrate-active enzyme updates from extrinsic microbes

    Jan Hendrik Hehemann;Amelia G. Kelly;Nicholas A. Pudlo;Eric C. Martens

  • Understanding the Biological Rationale for the Diversity of Cellulose-directed Carbohydrate-binding Modules in Prokaryotic Enzymes

    Anthony W. Blake;Lesley McCartney;James E. Flint;David N. Bolam

  • Restricted access of proteins to mannan polysaccharides in intact plant cell walls

    Susan E. Marcus;Anthony W. Blake;Thomas A. S. Benians;Kieran J. D. Lee

  • Characterization and affinity applications of cellulose-binding domains

    P. Tomme;A. Boraston;B. Mclean;J. Kormos

  • Iminosugar glycosidase inhibitors: structural and thermodynamic dissection of the binding of isofagomine and 1-deoxynojirimycin to beta-glucosidases.

    David L Zechel;Alisdair B Boraston;Tracey Gloster;Catherine M Boraston

  • Structural Biology of Pectin Degradation by Enterobacteriaceae

    D. Wade Abbott;Alisdair B. Boraston

  • Analysis of binding of the family 2a carbohydrate-binding module from Cellulomonas fimi xylanase 10A to cellulose: specificity and identification of functionally important amino acid residues.

    Bradley W. McLean;Mark R. Bray;Alisdair B. Boraston;Neil R. Gilkes

  • Ten years of CAZypedia: a living encyclopedia of carbohydrate-active enzymes

    Wade Abbott;Orly Alber;Ed Bayer;Jean-Guy Berrin

  • Differential Oligosaccharide Recognition by Evolutionarily-related β-1,4 and β-1,3 Glucan-binding Modules

    Alisdair B. Boraston;Didier Nurizzo;Valerie Notenboom;Valérie Ducros

  • Differential recognition of plant cell walls by microbial xylan-specific carbohydrate-binding modules

    Lesley McCartney;Anthony W. Blake;James Flint;David N. Bolam

  • Crystal structures of the family 9 carbohydrate-binding module from Thermotoga maritima xylanase 10A in native and ligand-bound forms.

    Valerie Notenboom;Alisdair B. Boraston;Douglas G. Kilburn;David R. Rose

  • Glycoside hydrolase carbohydrate-binding modules as molecular probes for the analysis of plant cell wall polymers.

    Lesley McCartney;Harry J Gilbert;David N Bolam;Alisdair B Boraston

  • Binding specificity and thermodynamics of a family 9 carbohydrate-binding module from Thermotoga maritima xylanase 10A.

    Boraston Ab;Creagh Al;Alam Mm;Kormos Jm

  • High-resolution crystal structures of the lectin-like xylan binding domain from Streptomyces lividans xylanase 10A with bound substrates reveal a novel mode of xylan binding.

    Valerie Notenboom;Alisdair B. Boraston;Spencer J. Williams;Douglas G. Kilburn

  • A sweet new wave: structures and mechanisms of enzymes that digest polysaccharides from marine algae.

    Jan-Hendrik Hehemann;Alisdair B Boraston;Mirjam Czjzek;Mirjam Czjzek

  • Family 6 Carbohydrate Binding Modules Recognize the Non-reducing End of β-1,3-Linked Glucans by Presenting a Unique Ligand Binding Surface

    Alicia Lammerts van Bueren;Carl Morland;Harry J. Gilbert;Alisdair B. Boraston

  • Recognition and hydrolysis of noncrystalline cellulose.

    Alisdair B. Boraston;Emily Kwan;Patrick Chiu;R. Antony J. Warren

  • Evidence that Family 35 Carbohydrate Binding Modules Display Conserved Specificity But Divergent Function.

    Cedric Montanier;Alicia Lammerts van Bueren;Claire Dumon;James E. Flint

Frequent Co-Authors

Harry J. Gilbert
Harry J. Gilbert Newcastle University
Douglas G. Kilburn
Douglas G. Kilburn University of British Columbia
David J. Vocadlo
David J. Vocadlo Simon Fraser University
Gideon J. Davies
Gideon J. Davies University of York
Robert D. Burke
Robert D. Burke University of Victoria
Mirjam Czjzek
Mirjam Czjzek Sorbonne University
David N. Bolam
David N. Bolam Newcastle University
Carlos M. G. A. Fontes
Carlos M. G. A. Fontes Nzytech (Portugal)
David R. Rose
David R. Rose University of Waterloo
José A. M. Prates
José A. M. Prates University of Lisbon

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