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Medicine

D-Index
78
Citations
20598
World Ranking
18099
National Ranking
9025

Overview

Dafydd G. Thomas is affiliated with the University of Michigan-Ann Arbor in the United States. Their research spans multiple areas primarily within medicine and biochemistry, genetics, and molecular biology, with particular focus on oncology and molecular biology subfields.

Their work has been published across various scientific journals, including the following venues:

  • Cancer Research
  • bioRxiv (Cold Spring Harbor Laboratory)
  • Molecular Cancer Research
  • Journal of Clinical Investigation
  • PLoS ONE

The research topics they explore cover a range of cancer-related fields, notably:

  • Cancer Immunotherapy and Biomarkers
  • Cancer Cells and Metastasis
  • Pancreatic and Hepatic Oncology Research
  • Cancer Genomics and Diagnostics
  • CAR-T cell therapy research
  • Cancer-related Molecular Pathways
  • Cancer Research and Treatments

Their recent publications include:

  • "TTK inhibition radiosensitizes basal-like breast cancer through impaired homologous recombination," 2020, Journal of Clinical Investigation
  • "PD-L1 expression on circulating tumor cells and platelets in patients with metastatic breast cancer," 2021, PLoS ONE
  • "A molecularly engineered, broad-spectrum anti-coronavirus lectin inhibits SARS-CoV-2 and MERS-CoV infection in vivo," 2022, Cell Reports Medicine
  • "Novel banana lectin CAR-T cells to target pancreatic tumors and tumor-associated stroma," 2023, Journal for ImmunoTherapy of Cancer
  • "PAICS, a De Novo Purine Biosynthetic Enzyme, Is Overexpressed in Pancreatic Cancer and Is Involved in Its Progression," 2020, Translational Oncology

Dafydd G. Thomas frequently collaborates with other researchers, including:

  • Theodore S. Lawrence (9 collaborations)
  • Arul M. Chinnaiyan (7 collaborations)
  • Daniel F. Hayes (7 collaborations)
  • Costanza Paoletti (6 collaborations)
  • Elizabeth P. Darga (5 collaborations)

Their scientific contributions address both clinical and molecular aspects of cancer, extending to immunotherapy approaches such as CAR-T cell therapy, and investigations into cancer biomarkers and diagnostics. Their work also encompasses viral infection mechanisms, evident in studies on broad-spectrum anti-coronavirus lectins.

Best Publications

  • Gene-expression profiles predict survival of patients with lung adenocarcinoma

    David G. Beer;Sharon L.R. Kardia;Chiang Ching Huang;Thomas J. Giordano

  • Aldehyde dehydrogenase in combination with CD133 defines angiogenic ovarian cancer stem cells that portend poor patient survival.

    Ines A. Silva;Shoumei Bai;Karen McLean;Kun Yang

  • Gene Expression Signatures for Predicting Prognosis of Squamous Cell and Adenocarcinomas of the Lung

    Mitch Raponi;Yi Zhang;Jack Yu;Guoan Chen

  • Proteomic Analysis of Lung Adenocarcinoma: Identification of a Highly Expressed Set of Proteins in Tumors

    Guoan Chen;Tarek G. Gharib;Chiang Ching Huang;Dafydd G. Thomas

  • Molecular classification of papillary thyroid carcinoma: distinct BRAF , RAS , and RET/PTC mutation-specific gene expression profiles discovered by DNA microarray analysis

    Thomas J Giordano;Rork Kuick;Dafydd G Thomas;David E Misek

  • Myeloid derived suppressor cells enhance stemness of cancer cells by inducing microRNA101 and suppressing the corepressor CtBP2

    Tracy X. Cui;Ilona Kryczek;Lili Zhao;Ende Zhao

  • Molecular Classification and Prognostication of Adrenocortical Tumors by Transcriptome Profiling

    Thomas J. Giordano;Rork Kuick;Tobias Else;Paul G. Gauger

  • Distinct Transcriptional Profiles of Adrenocortical Tumors Uncovered by DNA Microarray Analysis

    Thomas J. Giordano;Dafydd G. Thomas;Rork Kuick;Michelle Lizyness

  • Protein profiles associated with survival in lung adenocarcinoma

    Guoan Chen;Tarek G. Gharib;Hong Wang;Chiang Ching Huang

  • Efficacy of Imatinib in Aggressive Fibromatosis: Results of a Phase II Multicenter Sarcoma Alliance for Research through Collaboration (SARC) Trial

    Rashmi Chugh;J. Kyle Wathen;Shreyaskumar R. Patel;Robert G. Maki

  • HER2 Drives Luminal Breast Cancer Stem Cells in the Absence of HER2 Amplification: Implications for Efficacy of Adjuvant Trastuzumab

    Suthinee Ithimakin;Kathleen C. Day;Fayaz Malik;Qin Zen

  • Randomized trial of bolus phenylephrine or ephedrine for maintenance of arterial pressure during spinal anaesthesia for Caesarean section.

    D G Thomas;S C Robson;N Redfern;D Hughes

  • Phase II Multicenter Trial of Imatinib in 10 Histologic Subtypes of Sarcoma Using a Bayesian Hierarchical Statistical Model

    Rashmi Chugh;J. Kyle Wathen;Robert G. Maki;Robert S. Benjamin

  • Response of extraabdominal desmoid tumors to therapy with imatinib mesylate.

    Joseph Mace;J. Sybil Biermann;Vernon Sondak;Cornelius McGinn

  • Scavenging of CXCL12 by CXCR7 Promotes Tumor Growth and Metastasis of CXCR4-positive Breast Cancer Cells

    Kathryn E. Luker;Sarah A. Lewin;Laura Anne Mihalko;Bradley T. Schmidt

  • Cluster analysis of immunohistochemical profiles in synovial sarcoma, malignant peripheral nerve sheath tumor, and Ewing sarcoma

    Stephen H Olsen;Dafydd G Thomas;David R Lucas

  • Preclinical Targeting of the Type I Insulin-Like Growth Factor Receptor in Adrenocortical Carcinoma

    Ferdous M. Barlaskar;Aaron C. Spalding;Joanne H. Heaton;Rork Kuick

  • Requirement for Dot1l in murine postnatal hematopoiesis and leukemogenesis by MLL translocation

    Stephanie Y. Jo;Eric M. Granowicz;Ivan Maillard;Ivan Maillard;Dafydd Thomas

  • Genetic changes of Wnt pathway genes are common events in metaplastic carcinomas of the breast.

    Michael J. Hayes;Dafydd Thomas;Agnieszka Emmons;Thomas J. Giordano

  • GATA-3 expression identifies a high-risk subset of PTCL, NOS with distinct molecular and clinical features.

    Tianjiao Wang;Andrew L. Feldman;David A. Wada;Ye Lu

Frequent Co-Authors

Thomas J. Giordano
Thomas J. Giordano University of Michigan–Ann Arbor
David G. Beer
David G. Beer University of Michigan–Ann Arbor
Mark B. Orringer
Mark B. Orringer University of Michigan–Ann Arbor
Daniel F. Hayes
Daniel F. Hayes University of Michigan–Ann Arbor
Rork Kuick
Rork Kuick University of Michigan–Ann Arbor
Arul M. Chinnaiyan
Arul M. Chinnaiyan University of Michigan–Ann Arbor
Kent A. Griffith
Kent A. Griffith University of Michigan–Ann Arbor
Jeremy M. G. Taylor
Jeremy M. G. Taylor University of Michigan–Ann Arbor
Max S. Wicha
Max S. Wicha University of Michigan–Ann Arbor
Nallasivam Palanisamy
Nallasivam Palanisamy Henry Ford Health System

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