Stephen L. Lessnick

Overview

Best Publications

• RAS–RAF–MEK-dependent oxidative cell death involving voltage-dependent anion channels

  Nicholas Yagoda;Moritz von Rechenberg;Elma Zaganjor;Andras J. Bauer

  1441
  Citations

• Identification of genotype-selective antitumor agents using synthetic lethal chemical screening in engineered human tumor cells

  Sonam Dolma;Stephen L Lessnick;Stephen L Lessnick;William C Hahn;William C Hahn;Brent R Stockwell

  1290
  Citations

• A second Ewing's sarcoma translocation, t(21;22), fuses the EWS gene to another ETS–family transcription factor, ERG

  Poul H.B. Sorensen;Stephen L. Lessnick;Dolores Lopez-Terrada;Xian F. Liu

  891
  Citations

• Ewing sarcoma 11;22 translocation produces a chimeric transcription factor that requires the DNA-binding domain encoded by FLI1 for transformation.

  William A. May;Mikhail L. Gishizky;Mikhail L. Gishizky;Stephen L. Lessnick;Lynn B. Lunsford

  675
  Citations

• The PHD Finger of the Chromatin-Associated Protein ING2 Functions as a Nuclear Phosphoinositide Receptor

  Or Gozani;Philip Karuman;David R. Jones;Dmitri Ivanov

  652
  Citations

• The Ewing's sarcoma EWS/FLI-1 fusion gene encodes a more potent transcriptional activator and is a more powerful transforming gene than FLI-1.

  William A. May;Stephen L. Lessnick;Benjamin S. Braun;Michael Klemsz

  638
  Citations

• Comparison of MAPIE versus MAP in patients with a poor response to preoperative chemotherapy for newly diagnosed high-grade osteosarcoma (EURAMOS-1): an open-label, international, randomised controlled trial

  Neyssa M Marina;Sigbjørn Smeland;Stefan S Bielack;Mark Bernstein

  575
  Citations

• Survival and prognosis with osteosarcoma: outcomes in more than 2000 patients in the EURAMOS-1 (European and American Osteosarcoma Study) cohort

  Sigbjørn Smeland;Stefan S. Bielack;Jeremy Whelan;Mark Bernstein

  514
  Citations

• Expression profiling of EWS/FLI identifies NKX2.2 as a critical target gene in Ewing's sarcoma

  Richard Smith;Leah A. Owen;Deborah J. Trem;Jenny S. Wong

  411
  Citations

• β-Catenin–induced melanoma growth requires the downstream target Microphthalmia-associated transcription factor

  Hans R. Widlund;Martin A. Horstmann;E. Roydon Price;Junqing Cui

  335
  Citations

• Microsatellites as EWS/FLI response elements in Ewing's sarcoma

  Kunal Gangwal;Savita Sankar;Savita Sankar;Peter C. Hollenhorst;Michelle Kinsey;Michelle Kinsey

  333
  Citations

• The Ewing's sarcoma oncoprotein EWS/FLI induces a p53-dependent growth arrest in primary human fibroblasts

  Stephen L Lessnick;Caroline S Dacwag;Todd R Golub;Todd R Golub;Todd R Golub

  333
  Citations

• A Conditional Mouse Model of Synovial Sarcoma: Insights into a Myogenic Origin

  Malay Haldar;Jeffrey D. Hancock;Cheryl M. Coffin;Stephen L. Lessnick

  333
  Citations

• EWS–FLI1 increases transcription to cause R-loops and block BRCA1 repair in Ewing sarcoma

  Aparna Gorthi;July Carolina Romero;Eva Loranc;Lin Cao

  290
  Citations

• Promiscuous partnerships in Ewing's sarcoma.

  Savita Sankar;Stephen L. Lessnick;Stephen L. Lessnick

  259
  Citations

• Multiple domains mediate transformation by the Ewing's sarcoma EWS/FLI-1 fusion gene.

  Stephen L. Lessnick;Benjamin S. Braun;Christopher T. Denny;William A. May

  250
  Citations

• Identification of target genes for the Ewing's sarcoma EWS/FLI fusion protein by representational difference analysis.

  B S Braun;R Frieden;S L Lessnick;W A May

  240
  Citations

• Children's Oncology Group's 2013 blueprint for research: Bone tumors

  Richard Gorlick;Richard Gorlick;Katherine Janeway;Stephen Lessnick;R. Lor Randall

  238
  Citations

• NR0B1 Is Required for the Oncogenic Phenotype Mediated by EWS/FLI in Ewing's Sarcoma

  Michelle Kinsey;Richard Smith;Stephen L. Lessnick

  232
  Citations

• Recent advances in the molecular pathogenesis of Ewing's sarcoma.

  Elizabeth C. Toomey;Joshua D. Schiffman;Joshua D. Schiffman;Stephen L. Lessnick;Stephen L. Lessnick

  226
  Citations